4Z8N
Crystal structure of the erythrocyte-binding domain from Plasmodium vivax reticulocyte-binding protein 2a (PvRBP2a)
Summary for 4Z8N
| Entry DOI | 10.2210/pdb4z8n/pdb |
| Descriptor | Reticulocyte-binding protein 2a, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... (6 entities in total) |
| Functional Keywords | reticulocyte-binding, alpha-helical, cell invasion |
| Biological source | Plasmodium vivax (strain Salvador I) |
| Total number of polymer chains | 2 |
| Total formula weight | 69202.52 |
| Authors | Gruszczyk, J.,Tham, W.H. (deposition date: 2015-04-09, release date: 2015-12-16, Last modification date: 2016-01-27) |
| Primary citation | Gruszczyk, J.,Lim, N.T.,Arnott, A.,He, W.Q.,Nguitragool, W.,Roobsoong, W.,Mok, Y.F.,Murphy, J.M.,Smith, K.R.,Lee, S.,Bahlo, M.,Mueller, I.,Barry, A.E.,Tham, W.H. Structurally conserved erythrocyte-binding domain in Plasmodium provides a versatile scaffold for alternate receptor engagement. Proc.Natl.Acad.Sci.USA, 113:E191-E200, 2016 Cited by PubMed: 26715754DOI: 10.1073/pnas.1516512113 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.124 Å) |
Structure validation
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