6WNO

Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 243244

Summary for 6WNO

• Entry DOI: 10.2210/pdb6wno/pdb
• Related: 6WM9 6WN1
• Descriptor: 243244 Fab heavy chain, 243244 Fab light chain, Plasmodium vivax reticulocyte binding protein 2b (3 entities in total)
• Functional Keywords: invasion, plasmodium vivax, malaria, antibody complex, cell invasion
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 170013.09

Authors

Chan, L.J.,Dietrich, M.H.,Tham, W.H. (deposition date: 2020-04-23, release date: 2021-01-27, Last modification date: 2023-10-18)

• Primary citation: Chan, L.J.,Gandhirajan, A.,Carias, L.L.,Dietrich, M.H.,Vadas, O.,Visentin, R.,Franca, C.T.,Menant, S.,Soldati-Favre, D.,Mueller, I.,King, C.L.,Tham, W.H.; Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b.; Nat Commun, 12:1538-1538, 2021; PubMed: 33750786; DOI: 10.1038/s41467-021-21811-2

Experimental method

X-RAY DIFFRACTION (3.35 Å)