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6WOV
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BU of 6wov by Molmil
Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 wild type in complex with FKBP12.6
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
Authors:Iyer, K.A, Hu, Y, Nayak, A.R, Kurebayashi, N, Murayama, T, Samso, M.
Deposit date:2020-04-25
Release date:2020-08-05
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM.
Sci Adv, 6, 2020
6WOU
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BU of 6wou by Molmil
Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 mutant R176Q in complex with FKBP12.6 in nanodisc
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
Authors:Iyer, K.A, Hu, Y, Kurebayashi, N, Murayama, T, Samso, M.
Deposit date:2020-04-25
Release date:2020-08-05
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM.
Sci Adv, 6, 2020
7UMZ
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BU of 7umz by Molmil
Cryo-EM structure of rabbit RyR1 in the presence of high Mg2+ and AMP-PCP in nanodisc
Descriptor: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
Authors:Nayak, A.R, Samso, M.
Deposit date:2022-04-08
Release date:2023-04-12
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Interplay between Mg2+ and Ca2+ at multiple sites of the ryanodine receptor
Biorxiv, 2024
6WOT
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BU of 6wot by Molmil
Cryo-EM structure of recombinant rabbit Ryanodine Receptor type 1 mutant R164C in complex with FKBP12.6
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION
Authors:Iyer, K.A, Hu, Y, Kurebayashi, N, Murayama, T, Samso, M.
Deposit date:2020-04-25
Release date:2020-08-05
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM.
Sci Adv, 6, 2020
5L1D
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BU of 5l1d by Molmil
Structure of rabbit RyR2 in complex with FKBP12.6 in a closed state (conformation C1)
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor
Authors:Dhindwal, S, Lobo, J.J, Samso, M.
Deposit date:2016-07-29
Release date:2017-05-24
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (11 Å)
Cite:A cryo-EM-based model of phosphorylation- and FKBP12.6-mediated allosterism of the cardiac ryanodine receptor.
Sci.Signal., 10, 2017
7K0T
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BU of 7k0t by Molmil
Cryo-EM structure of rabbit RyR1 in the presence of AMP-PCP in nanodisc
Descriptor: PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, RyR1, ZINC ION
Authors:Nayak, A.R, Samso, M.
Deposit date:2020-09-05
Release date:2021-09-22
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
7K0S
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BU of 7k0s by Molmil
Cryo-EM structure of rabbit RyR1 in the presence of Mg2+ and AMP-PCP in nanodisc
Descriptor: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, RyR1, ...
Authors:Nayak, A.R, Samso, M.
Deposit date:2020-09-05
Release date:2021-09-22
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Interplay between Mg2+ and Ca2+ at multiple sites of the ryanodine receptor
Biorxiv, 2024
8DTZ
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BU of 8dtz by Molmil
Recombinant mouse RyR2 triple phosphonull mutant S2807A/S2813A/S2030A in complex with FKBP12.6 and nanodisc under closed-state conditions
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
Authors:Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
Deposit date:2022-07-26
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Recombinant mouse RyR2 triple phosphonull mutant S2807A/S2813A/S2030A in complex with FKBP12.6 and nanodisc under closed-state conditions
To Be Published
8DTY
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BU of 8dty by Molmil
Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under closed-state conditions
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
Authors:Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
Deposit date:2022-07-26
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under closed-state conditions
To Be Published
8DZF
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BU of 8dzf by Molmil
Cryo-EM structure of bundle-forming pilus extension ATPase from E.coli in the presence of AMP-PNP (class-2)
Descriptor: BfpD, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ZINC ION
Authors:Nayak, A.R, Zhao, J, Donnenberg, M.S, Samso, M.
Deposit date:2022-08-07
Release date:2022-10-26
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:Cryo-EM Structure of the Type IV Pilus Extension ATPase from Enteropathogenic Escherichia coli.
Mbio, 13, 2022
8DZE
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BU of 8dze by Molmil
Cryo-EM structure of bundle-forming pilus extension ATPase from E. coli in the presence of AMP-PNP (class-1)
Descriptor: BfpD, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ZINC ION
Authors:Nayak, A.R, Zhao, J, Donnenberg, M.S, Samso, M.
Deposit date:2022-08-07
Release date:2022-10-26
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:Cryo-EM Structure of the Type IV Pilus Extension ATPase from Enteropathogenic Escherichia coli.
Mbio, 13, 2022
8DZG
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BU of 8dzg by Molmil
Cryo-EM structure of bundle-forming pilus extension ATPase from E.coli in the presence of ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BfpD, MAGNESIUM ION, ...
Authors:Nayak, A.R, Zhao, J, Donnenberg, M.S, Samso, M.
Deposit date:2022-08-07
Release date:2022-10-26
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM Structure of the Type IV Pilus Extension ATPase from Enteropathogenic Escherichia coli.
Mbio, 13, 2022
8DVV
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BU of 8dvv by Molmil
Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions
Descriptor: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
Authors:Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
Deposit date:2022-07-29
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions
To Be Published
7TDJ
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BU of 7tdj by Molmil
Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in closed-inactivated conformation class 1(Dataset-A)
Descriptor: CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ...
Authors:Nayak, A.R, Samso, M.
Deposit date:2021-12-31
Release date:2022-03-09
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
7TDG
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BU of 7tdg by Molmil
Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in inactivated conformation (Dataset-A)
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
Authors:Nayak, A.R, Samso, M.
Deposit date:2021-12-31
Release date:2022-03-09
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
7TDH
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BU of 7tdh by Molmil
Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in open conformation
Descriptor: CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ...
Authors:Nayak, A.R, Samso, M.
Deposit date:2021-12-31
Release date:2022-03-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
7TDK
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BU of 7tdk by Molmil
Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in closed-inactivated conformation class 3 (Dataset-A)
Descriptor: CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ...
Authors:Nayak, A.R, Samso, M.
Deposit date:2021-12-31
Release date:2022-03-09
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
7TDI
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BU of 7tdi by Molmil
Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in closed-inactivated conformation class 2 (Dataset-A)
Descriptor: CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ...
Authors:Nayak, A.R, Samso, M.
Deposit date:2021-12-31
Release date:2022-03-09
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
7T64
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BU of 7t64 by Molmil
Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6 embedded in lipidic nanodisc in the closed state
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION
Authors:Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
Deposit date:2021-12-13
Release date:2022-07-20
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Molecular mechanism of the severe MH/CCD mutation Y522S in skeletal ryanodine receptor (RyR1) by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T65
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BU of 7t65 by Molmil
Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6 embedded in lipidic nanodisc in the open state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
Authors:Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
Deposit date:2021-12-13
Release date:2022-07-20
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (4.05 Å)
Cite:Molecular mechanism of the severe MH/CCD mutation Y522S in skeletal ryanodine receptor (RyR1) by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022

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