7UMZ

Cryo-EM structure of rabbit RyR1 in the presence of high Mg2+ and AMP-PCP in nanodisc

This is a non-PDB format compatible entry.

Summary for 7UMZ

• Entry DOI: 10.2210/pdb7umz/pdb
• Related: 7K0S 7K0T
• EMDB information: 26610
• Descriptor: Ryanodine receptor 1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ZINC ION, ... (6 entities in total)
• Functional Keywords: ryanodine receptor, ryr1, intracellular calcium channel, mg2+, inhibition, excitation-contraction coupling, transport protein
• Biological source: Oryctolagus cuniculus (rabbit)
• Total number of polymer chains: 4
• Total formula weight: 2180227.04

Authors

Nayak, A.R.,Samso, M. (deposition date: 2022-04-08, release date: 2023-04-12, Last modification date: 2024-03-06)

• Primary citation: Nayak, A.R.,Rangubpit, W.,Will, A.H.,Hu, Y.,Castro-Hartmann, P.,Lobo, J.J.,Dryden, K.,Lamb, G.D.,Sompornpisut, P.,Samso, M.; Interplay between Mg2+ and Ca2+ at multiple sites of the ryanodine receptor; Biorxiv, 2024; DOI: 10.1101/2024.02.16.580716

Experimental method

ELECTRON MICROSCOPY (3.09 Å)