7K0S

Cryo-EM structure of rabbit RyR1 in the presence of Mg2+ and AMP-PCP in nanodisc

This is a non-PDB format compatible entry.

Summary for 7K0S

• Entry DOI: 10.2210/pdb7k0s/pdb
• EMDB information: 22596 22597 22615 22616
• Descriptor: RyR1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ZINC ION, ... (4 entities in total)
• Functional Keywords: ryanodine receptor, ryr1, intracellular calcium channel, mg2+, inhibition, excitation-contraction coupling, transport protein
• Biological source: Oryctolagus cuniculus (rabbit)
• Total number of polymer chains: 4
• Total formula weight: 2137056.99

Authors

Nayak, A.R.,Samso, M. (deposition date: 2020-09-05, release date: 2021-09-22, Last modification date: 2024-05-22)

• Primary citation: Nayak, A.R.,Rangubpit, W.,Will, A.H.,Hu, Y.,Castro-Hartmann, P.,Lobo, J.J.,Dryden, K.,Lamb, G.D.,Sompornpisut, P.,Samso, M.; Interplay between Mg2+ and Ca2+ at multiple sites of the ryanodine receptor; Nat Commun, 15:4115-, 2024; DOI: 10.1038/s41467-024-48292-3

Experimental method

ELECTRON MICROSCOPY (4.5 Å)