4TZ4
| Crystal Structure of Human Cereblon in Complex with DDB1 and Lenalidomide | 分子名称: | DNA damage-binding protein 1, Protein cereblon, S-Lenalidomide, ... | 著者 | Chamberlain, P.P, Pagarigan, B, Delker, S, Leon, B, Riley, M. | 登録日 | 2014-07-09 | 公開日 | 2014-08-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | Structural Basis for Responsiveness to Thalidomide-Analog Drugs Defined by the Crystal Structure of the Human Cereblon:DDB1:Lenalidomide Complex To Be Published
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1LWU
| Crystal structure of fragment D from lamprey fibrinogen complexed with the peptide Gly-His-Arg-Pro-amide | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yang, Z, Spraggon, G, Pandi, L, Everse, S.J, Riley, M, Doolittle, R.F. | 登録日 | 2002-06-03 | 公開日 | 2002-08-23 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of fragment D from lamprey fibrinogen complexed with the peptide Gly-His-Arg-Pro-amide. Biochemistry, 41, 2002
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1EI3
| CRYSTAL STRUCTURE OF NATIVE CHICKEN FIBRINOGEN | 分子名称: | FIBRINOGEN | 著者 | Yang, Z, Mochalkin, I, Veerapandian, L, Riley, M, Doolittle, R.F. | 登録日 | 2000-02-23 | 公開日 | 2000-05-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (5.5 Å) | 主引用文献 | Crystal structure of native chicken fibrinogen at 5.5-A resolution. Proc.Natl.Acad.Sci.USA, 97, 2000
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3GHG
| Crystal Structure of Human Fibrinogen | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A knob, B knob, ... | 著者 | Doolittle, R.F, Kollman, J.M, Sawaya, M.R, Pandi, L, Riley, M. | 登録日 | 2009-03-03 | 公開日 | 2009-05-19 | 最終更新日 | 2023-05-03 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of human fibrinogen. Biochemistry, 48, 2009
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1FZC
| CRYSTAL STRUCTURE OF FRAGMENT DOUBLE-D FROM HUMAN FIBRIN WITH TWO DIFFERENT BOUND LIGANDS | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Everse, S.J, Spraggon, G, Veerapandian, L, Riley, M, Doolittle, R.F. | 登録日 | 1998-05-19 | 公開日 | 1998-10-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of fragment double-D from human fibrin with two different bound ligands. Biochemistry, 37, 1998
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1M1J
| Crystal structure of native chicken fibrinogen with two different bound ligands | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Yang, Z, Kollman, J.M, Pandi, L, Doolittle, R.F. | 登録日 | 2002-06-19 | 公開日 | 2002-06-26 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structure of Native Chicken Fibrinogen at 2.7 A Resolution Biochemistry, 40, 2001
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4TZU
| Crystal Structure of Murine Cereblon in Complex with Pomalidomide | 分子名称: | Protein cereblon, S-Pomalidomide, SULFATE ION, ... | 著者 | Chamberlain, P.P, Pagarigan, B, Delker, S, Leon, B. | 登録日 | 2014-07-10 | 公開日 | 2014-08-06 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Basis for Responsiveness to Thalidomide-Analog Drugs Defined by the Crystal Structure of the Human Cereblon:DDB1:Lenalidomide Complex to be published
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4TZC
| Crystal Structure of Murine Cereblon in Complex with Thalidomide | 分子名称: | Protein cereblon, S-Thalidomide, SULFATE ION, ... | 著者 | Chamberlain, P.P, Pagarigan, B, Delker, S, Leon, B. | 登録日 | 2014-07-10 | 公開日 | 2014-08-06 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Structural Basis for Responsiveness to Thalidomide-Analog Drugs Defined by the Crystal Structure of the Human Cereblon:DDB1:Lenalidomide Complex to be published
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5HXB
| Cereblon in complex with DDB1, CC-885, and GSPT1 | 分子名称: | 1-(3-chloro-4-methylphenyl)-3-({2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-2,3-dihydro-1H-isoindol-5-yl}methyl)urea, DNA damage-binding protein 1, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, ... | 著者 | Chamberlain, P.P, Matyskiela, M, Pagarigan, B. | 登録日 | 2016-01-30 | 公開日 | 2016-06-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase. Nature, 535, 2016
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1N86
| Crystal structure of human D-dimer from cross-linked fibrin complexed with GPR and GHRPLDK peptide ligands. | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, CALCIUM ION, Fibrin alpha/alpha-E chain, ... | 著者 | Yang, Z, Pandi, L, Doolittle, R.F. | 登録日 | 2002-11-19 | 公開日 | 2003-01-07 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface. Biochemistry, 41, 2002
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3WX2
| Mouse Cereblon thalidomide binding domain, native | 分子名称: | Protein cereblon, SULFATE ION, ZINC ION | 著者 | Mori, T, Ito, T, Hirano, Y, Yamaguchi, Y, Handa, H, Hakoshima, T. | 登録日 | 2014-07-10 | 公開日 | 2014-08-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs Nat.Struct.Mol.Biol., 21, 2014
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3WX1
| Mouse Cereblon thalidomide binding domain, selenomethionine derivative | 分子名称: | Protein cereblon, SULFATE ION, ZINC ION | 著者 | Mori, T, Ito, T, Hirano, Y, Yamaguchi, Y, Handa, H, Hakoshima, T. | 登録日 | 2014-07-10 | 公開日 | 2014-08-06 | 最終更新日 | 2014-09-17 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs Nat.Struct.Mol.Biol., 21, 2014
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3H32
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3OCD
| Diheme SoxAX - C236M mutant | 分子名称: | HEME C, SoxA, SoxX | 著者 | Maher, M.J. | 登録日 | 2010-08-09 | 公開日 | 2011-05-18 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Diheme SoxAX proteins - insights into structure and function of the active site To be Published
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3OA8
| Diheme SoxAX | 分子名称: | HEME C, SULFATE ION, SoxA, ... | 著者 | Maher, M.J. | 登録日 | 2010-08-04 | 公開日 | 2011-05-18 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Diheme SoxAX proteins - insights into structure and function of the active site To be Published
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5V3O
| Cereblon in complex with DDB1 and CC-220 | 分子名称: | (3S)-3-[4-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)-1-oxo-1,3-dihydro-2H-isoindol-2-yl]piperidine-2,6-dione, DNA damage-binding protein 1, Protein cereblon, ... | 著者 | Matyskiela, M, Pagarigan, B, Chamberlain, P. | 登録日 | 2017-03-07 | 公開日 | 2017-05-03 | 最終更新日 | 2018-02-07 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos. J. Med. Chem., 61, 2018
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1N8E
| Fragment Double-D from Human Fibrin | 分子名称: | Fibrin alpha/alpha-E chain, Fibrin beta chain, Fibrin gamma chain | 著者 | Yang, Z, Pandi, L, Doolittle, R.F. | 登録日 | 2002-11-20 | 公開日 | 2003-01-07 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | 主引用文献 | The Crystal Structure of Fragment Double-D from Cross-Linked Lamprey Fibrin Reveals Isopeptide Linkages across an Unexpected D-D Interface Biochemistry, 41, 2002
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