3WX1

Mouse Cereblon thalidomide binding domain, selenomethionine derivative

Summary for 3WX1

Entry DOI	10.2210/pdb3wx1/pdb
Related	3wx2
Descriptor	Protein cereblon, ZINC ION, SULFATE ION, ... (4 entities in total)
Functional Keywords	zinc finger, e3 ubiquitin ligase, metal binding protein
Biological source	Mus musculus (mouse)
Cellular location	Cytoplasm (By similarity): Q8C7D2
Total number of polymer chains	2
Total formula weight	25373.19
Authors	Mori, T.,Ito, T.,Hirano, Y.,Yamaguchi, Y.,Handa, H.,Hakoshima, T. (deposition date: 2014-07-10, release date: 2014-08-06, Last modification date: 2014-09-17)
Primary citation	Chamberlain, P.P.,Lopez-Girona, A.,Miller, K.,Carmel, G.,Pagarigan, B.,Chie-Leon, B.,Rychak, E.,Corral, L.G.,Ren, Y.J.,Wang, M.,Riley, M.,Delker, S.L.,Ito, T.,Ando, H.,Mori, T.,Hirano, Y.,Handa, H.,Hakoshima, T.,Daniel, T.O.,Cathers, B.E. Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs Nat.Struct.Mol.Biol., 21:803-809, 2014 Cited by PubMed: 25108355 DOI: 10.1038/nsmb.2874 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.93 Å)

Structure validation