3WX2
Mouse Cereblon thalidomide binding domain, native
Summary for 3WX2
Entry DOI | 10.2210/pdb3wx2/pdb |
Related | 3WX1 |
Descriptor | Protein cereblon, ZINC ION, SULFATE ION, ... (4 entities in total) |
Functional Keywords | zinc finger, e3 ubiquitin ligase, metal binding protein |
Biological source | Mus musculus (mouse) |
Cellular location | Cytoplasm (By similarity): Q8C7D2 |
Total number of polymer chains | 2 |
Total formula weight | 25185.61 |
Authors | Mori, T.,Ito, T.,Hirano, Y.,Yamaguchi, Y.,Handa, H.,Hakoshima, T. (deposition date: 2014-07-10, release date: 2014-08-06, Last modification date: 2023-11-08) |
Primary citation | Chamberlain, P.P.,Lopez-Girona, A.,Miller, K.,Carmel, G.,Pagarigan, B.,Chie-Leon, B.,Rychak, E.,Corral, L.G.,Ren, Y.J.,Wang, M.,Riley, M.,Delker, S.L.,Ito, T.,Ando, H.,Mori, T.,Hirano, Y.,Handa, H.,Hakoshima, T.,Daniel, T.O.,Cathers, B.E. Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs Nat.Struct.Mol.Biol., 21:803-809, 2014 Cited by PubMed: 25108355DOI: 10.1038/nsmb.2874 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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