1X7S
 
 | | The X-ray crystallographic structure of the amyloidogenic variant TTR Tyr78Phe | | 分子名称: | Transthyretin | | 著者 | Neto-Silva, R.M, Macedo-Ribeiro, S, Pereira, P.J.B, Saraiva, M.J, Damas, A.M. | | 登録日 | 2004-08-16 | | 公開日 | 2005-03-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | X-ray crystallographic studies of two transthyretin variants: further insights into amyloidogenesis.
Acta Crystallogr.,Sect.D, 61, 2005
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1X7T
 | | Structure of TTR R104H: a non-amyloidogenic variant with protective clinical effects | | 分子名称: | Transthyretin | | 著者 | Neto-Silva, R.M, Macedo-Ribeiro, S, Pereira, P.J.B, Coll, M, Saraiva, M.J, Damas, A.M. | | 登録日 | 2004-08-16 | | 公開日 | 2005-03-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | X-ray crystallographic studies of two transthyretin variants: further insights into amyloidogenesis.
Acta Crystallogr.,Sect.D, 61, 2005
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4WZY
 | | Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway (ATP complex) | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Maltokinase | | 著者 | Fraga, J, Empadinhas, N, Pereira, P.J.B, Macedo-Ribeiro, S. | | 登録日 | 2014-11-20 | | 公開日 | 2015-02-11 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway.
Sci Rep, 5, 2015
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4U98
 | | Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway (AppCp complex) | | 分子名称: | MAGNESIUM ION, Maltokinase, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | | 著者 | Fraga, J, Empadinhas, N, Pereira, P.J.B, Macedo-Ribeiro, S. | | 登録日 | 2014-08-05 | | 公開日 | 2015-02-11 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway.
Sci Rep, 5, 2015
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4U94
 | | Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway | | 分子名称: | MAGNESIUM ION, Maltokinase | | 著者 | Fraga, J, Empadinhas, N, Pereira, P.J.B, Macedo-Ribeiro, S. | | 登録日 | 2014-08-05 | | 公開日 | 2015-02-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.473 Å) | | 主引用文献 | Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway.
Sci Rep, 5, 2015
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5TNY
 | | HTRA2 G399S mutant | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Serine protease HTRA2, mitochondrial | | 著者 | Merski, M, Barbosa Pereira, P.J, Macedo-Ribeiro, S. | | 登録日 | 2016-10-15 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2.
Cell Death Dis, 8, 2017
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5TO0
 | | HTRA2 S276C mutant | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Serine protease HTRA2, mitochondrial | | 著者 | Merski, M, Barbosa Pereira, P.J, Macedo-Ribeiro, S. | | 登録日 | 2016-10-15 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2.
Cell Death Dis, 8, 2017
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5TO1
 | | HtrA2 exposed (L266R, F303A) mutant | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Serine protease HTRA2, ... | | 著者 | Merski, M, Barbosa Pereira, P.J, Macedo-Ribeiro, S. | | 登録日 | 2016-10-15 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2.
Cell Death Dis, 8, 2017
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2I5P
 | | Crystal structure of glyceraldehyde-3-phosphate dehydrogenase isoform 1 from K. marxianus | | 分子名称: | BETA-MERCAPTOETHANOL, Glyceraldehyde-3-phosphate dehydrogenase 1, alpha-D-glucopyranose | | 著者 | Ferreira-da-Silva, F, Pereira, P.J.B, Gales, L, Moradas-Ferreira, P, Damas, A.M. | | 登録日 | 2006-08-25 | | 公開日 | 2006-09-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The Crystal and Solution Structures of Glyceraldehyde-3-phosphate Dehydrogenase Reveal Different Quaternary Structures.
J.Biol.Chem., 281, 2006
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2ODY
 | | Thrombin-bound boophilin displays a functional and accessible reactive-site loop | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Boophilin, PHOSPHATE ION, ... | | 著者 | Macedo-Ribeiro, S, Fuentes-Prior, P, Pereira, P.J.B. | | 登録日 | 2006-12-27 | | 公開日 | 2008-01-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Isolation, cloning and structural characterisation of boophilin, a multifunctional kunitz-type proteinase inhibitor from the cattle tick.
Plos One, 3, 2008
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3QNE
 | | Candida albicans seryl-tRNA synthetase | | 分子名称: | Seryl-tRNA synthetase, cytoplasmic | | 著者 | Rocha, R, Santos, M.A, Pereira, P.J.B, Macedo-Ribeiro, S. | | 登録日 | 2011-02-08 | | 公開日 | 2011-08-03 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogen.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3QO5
 | | Crystal Structure of the seryl-tRNA synthetase from Candida albicans | | 分子名称: | Seryl-tRNA synthetase, cytoplasmic | | 著者 | Rocha, R, Santos, M.A, Pereira, P.J.B, Macedo-Ribeiro, S. | | 登録日 | 2011-02-09 | | 公開日 | 2011-08-03 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogen.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3QO7
 | | Crystal structure of the seryl-tRNA synthetase from Candida albicans | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Seryl-tRNA synthetase, cytoplasmic | | 著者 | Rocha, R, Santos, M.A, Pereira, P.J.B, Macedo-Ribeiro, S. | | 登録日 | 2011-02-09 | | 公開日 | 2011-08-03 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogen.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3QO8
 | | Crystal Structure of seryl-tRNA synthetase from Candida albicans | | 分子名称: | 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, MAGNESIUM ION, Seryl-tRNA synthetase, ... | | 著者 | Rocha, R, Santos, M.A, Pereira, P.J.B, Macedo-Ribeiro, S. | | 登録日 | 2011-02-09 | | 公開日 | 2011-08-03 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Unveiling the structural basis for translational ambiguity tolerance in a human fungal pathogen.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3U8R
 | | Human thrombin complexed with D-Phe-Pro-D-Arg-Ile | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Figueiredo, A.C, Clement, C.C, Philipp, M, Pereira, P.J.B. | | 登録日 | 2011-10-17 | | 公開日 | 2012-05-23 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | Rational design and characterization of D-Phe-Pro-D-Arg-derived direct thrombin inhibitors.
Plos One, 7, 2012
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3U8T
 | | Human thrombin complexed with D-Phe-Pro-D-Arg-Cys | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Figueiredo, A.C, Clement, C.C, Philipp, M, Pereira, P.J.B. | | 登録日 | 2011-10-17 | | 公開日 | 2012-04-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.861 Å) | | 主引用文献 | Rational design and characterization of d-phe-pro-d-arg-derived direct thrombin inhibitors.
Plos One, 7, 2012
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4BOH
 | | Madanins (MEROPS I53) are cleaved by thrombin and factor Xa | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, SULFATE ION, ... | | 著者 | Figueiredo, A.C, deSanctis, D, Pereira, P.J.B. | | 登録日 | 2013-05-20 | | 公開日 | 2013-09-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.595 Å) | | 主引用文献 | The Tick-Derived Anticoagulant Madanin is Processed by Thrombin and Factor Xa.
Plos One, 8, 2013
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4E05
 | | Anophelin from the malaria vector inhibits thrombin through a novel reverse-binding mechanism | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, Salivary anti-thrombin peptide anophelin, ... | | 著者 | Figueiredo, A.C, de Sanctis, D, Gutierrez-Gallego, R, Cereija, T.B, Macedo-Ribeiro, S, Fuentes-Prior, P, Pereira, P.J.B. | | 登録日 | 2012-03-02 | | 公開日 | 2012-12-05 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.304 Å) | | 主引用文献 | Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4E06
 | | Anophelin from the malaria vector inhibits thrombin through a novel reverse-binding mechanism | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, Salivary anti-thrombin peptide anophelin, ... | | 著者 | Figueiredo, A.C, de Sanctis, D, Gutierrez-Gallego, R, Cereija, T.B, Macedo-Ribeiro, S, Fuentes-Prior, P, Pereira, P.J.B. | | 登録日 | 2012-03-02 | | 公開日 | 2012-12-05 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.196 Å) | | 主引用文献 | Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3U8O
 | | Human thrombin complexed with D-Phe-Pro-D-Arg-D-Thr | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Figueiredo, A.C, Clement, C.C, Philipp, M, Pereira, P.J.B. | | 登録日 | 2011-10-17 | | 公開日 | 2012-05-23 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | | 主引用文献 | Rational design and characterization of D-Phe-Pro-D-Arg-derived direct thrombin inhibitors.
Plos One, 7, 2012
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1T31
 | | A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[3-({METHYL[1-(2-NAPHTHOYL)PIPERIDIN-4-YL]AMINO}CARBONYL)-2-NAPHTHYL]-1-(1-NAPHTHYL)-2-OXOETHYLPHOSPHONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | de Garavilla, L, Greco, M.N, Giardino, E.C, Wells, G.I, Haertlein, B.J, Kauffman, J.A, Corcoran, T.W, Derian, C.K, Eckardt, A.J, Abraham, W.M, Sukumar, N, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E, Andrade-Gordon, P, Damiano, B.P, Maryanoff, B.E, Pereira, P.J.B, Wang, Z.M, Rubin, H, Huber, R, Bode, W, Schechter, N.M, Strobl, S. | | 登録日 | 2004-04-23 | | 公開日 | 2005-03-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo.
J.Biol.Chem., 280, 2005
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