4BOH

Madanins (MEROPS I53) are cleaved by thrombin and factor Xa

Summary for 4BOH

Entry DOI	10.2210/pdb4boh/pdb
Descriptor	THROMBIN HEAVY CHAIN, THROMBIN LIGHT CHAIN, THROMBIN INHIBITOR MADANIN 1, ... (7 entities in total)
Functional Keywords	hydrolase-inhibitor complex, coagulation inhibitor, protease, macromolecular recognition, hydrolase/inhibitor
Biological source	HAEMAPHYSALIS LONGICORNIS More
Total number of polymer chains	5
Total formula weight	75503.45
Authors	Figueiredo, A.C.,deSanctis, D.,Pereira, P.J.B. (deposition date: 2013-05-20, release date: 2013-09-04, Last modification date: 2023-12-20)
Primary citation	Figueiredo, A.C.,De Sanctis, D.,Pereira, P.J. The Tick-Derived Anticoagulant Madanin is Processed by Thrombin and Factor Xa. Plos One, 8:71866-, 2013 Cited by PubMed: 23951260 DOI: 10.1371/JOURNAL.PONE.0071866 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.595 Å)

Structure validation