4K96
| Structure of Binary Complex of cGAS with Bound dsDNA | Descriptor: | Cyclic GMP-AMP synthase, DNA-F, DNA-R, ... | Authors: | Gao, P, Wu, Y, Patel, D.J. | Deposit date: | 2013-04-19 | Release date: | 2013-05-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.084 Å) | Cite: | Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
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4K98
| Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG | Descriptor: | Cyclic GMP-AMP synthase, DNA-F, DNA-R, ... | Authors: | Gao, P, Wu, Y, Patel, D.J. | Deposit date: | 2013-04-19 | Release date: | 2013-05-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
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4K8V
| Structure of cyclic GMP-AMP Synthase (cGAS) | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION | Authors: | Gao, P, Wu, Y, Patel, D.J. | Deposit date: | 2013-04-18 | Release date: | 2013-05-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
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4KXT
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4K85
| Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 12:0 Ceramide-1-Phosphate (12:0-C1P) | Descriptor: | (2S,3R,4E)-2-(dodecanoylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Glycolipid transfer protein domain-containing protein 1 | Authors: | Simanshu, D.K, Brown, R.E, Patel, D.J. | Deposit date: | 2013-04-17 | Release date: | 2013-07-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids. Nature, 500, 2013
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4K8N
| Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 18:1 Ceramide-1-Phosphate (18:1-C1P) | Descriptor: | (2S,3R,4Z)-3-hydroxy-2-[(9E)-octadec-9-enoylamino]octadec-4-en-1-yl dihydrogen phosphate, Glycolipid transfer protein domain-containing protein 1 | Authors: | Simanshu, D.K, Brown, R.E, Patel, D.J. | Deposit date: | 2013-04-18 | Release date: | 2013-07-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.102 Å) | Cite: | Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids. Nature, 500, 2013
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4KF6
| Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 8:0 Ceramide-1-Phosphate (8:0-C1P) | Descriptor: | (2S,3R,4E)-3-hydroxy-2-(octanoylamino)octadec-4-en-1-yl dihydrogen phosphate, Glycolipid transfer protein domain-containing protein 1 | Authors: | Simanshu, D.K, Brown, R.E, Patel, D.J. | Deposit date: | 2013-04-26 | Release date: | 2013-07-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.195 Å) | Cite: | Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids. Nature, 500, 2013
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4K99
| Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppdG(2 ,5 )pdG | Descriptor: | 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, 3'-deoxy-guanosine 5'-monophosphate, Cyclic GMP-AMP synthase, ... | Authors: | Gao, P, Wu, Y, Patel, D.J. | Deposit date: | 2013-04-19 | Release date: | 2013-05-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
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4JVH
| Structure of the star domain of quaking protein in complex with RNA | Descriptor: | Protein quaking, RNA (5'-R(*UP*UP*CP*AP*CP*UP*AP*AP*CP*AP*A)-3'), SULFATE ION | Authors: | Teplova, M, Hafner, M, Teplov, D, Essig, K, Tuschl, T, Patel, D.J. | Deposit date: | 2013-03-25 | Release date: | 2013-05-08 | Method: | X-RAY DIFFRACTION (3.501 Å) | Cite: | Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites. Genes Dev., 27, 2013
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4JVY
| Structure of the STAR (signal transduction and activation of RNA) domain of GLD-1 bound to RNA | Descriptor: | Female germline-specific tumor suppressor gld-1, RNA (5'-R(P*CP*UP*AP*AP*CP*AP*A)-3') | Authors: | Teplova, M, Hafner, M, Teplov, D, Essig, K, Tuschl, T, Patel, D.J. | Deposit date: | 2013-03-26 | Release date: | 2013-05-08 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.853 Å) | Cite: | Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites. Genes Dev., 27, 2013
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4LOH
| Crystal structure of hSTING(H232) in complex with c[G(2',5')pA(3',5')p] | Descriptor: | Stimulator of interferon genes protein, cGAMP | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2013-07-12 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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4LOJ
| Crystal structure of mSting in complex with c[G(2',5')pA(3',5')p] | Descriptor: | Stimulator of interferon genes protein, cGAMP | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2013-07-12 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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4JOL
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4KBR
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4K84
| Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 16:0 ceramide-1-phosphate (16:0-C1P) | Descriptor: | (2S,3R,4E)-2-(hexadecanoylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Glycolipid transfer protein domain-containing protein 1 | Authors: | Simanshu, D.K, Brown, R.E, Patel, D.J. | Deposit date: | 2013-04-17 | Release date: | 2013-07-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.897 Å) | Cite: | Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids. Nature, 500, 2013
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4K9A
| Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pG(2 ,5 )pA | Descriptor: | ADENOSINE-5'-MONOPHOSPHATE, Cyclic GMP-AMP synthase, DNA-F, ... | Authors: | Gao, P, Wu, Y, Patel, D.J. | Deposit date: | 2013-04-19 | Release date: | 2013-05-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.264 Å) | Cite: | Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell(Cambridge,Mass.), 153, 2013
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4LOI
| Crystal structure of hSTING(H232) in complex with c[G(2',5')pA(2',5')p] | Descriptor: | 2-amino-9-[(1R,3R,6R,8R,9R,11S,14R,16R,17R,18R)-16-(6-amino-9H-purin-9-yl)-3,11,17,18-tetrahydroxy-3,11-dioxido-2,4,7,10,12,15-hexaoxa-3,11-diphosphatricyclo[12.2.1.1~6,9~]octadec-8-yl]-1,9-dihydro-6H-purin-6-one, PHOSPHATE ION, Stimulator of interferon genes protein | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2013-07-12 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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4LOK
| Crystal structure of mSting in complex with c[G(3',5')pA(3',5')p] | Descriptor: | 2-amino-9-[(2R,3R,3aR,5S,7aS,9R,10R,10aR,12R,14aS)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, Stimulator of interferon genes protein | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2013-07-12 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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4LOL
| Crystal structure of mSting in complex with DMXAA | Descriptor: | (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, Stimulator of interferon genes protein | Authors: | Gao, P, Patel, D.J. | Deposit date: | 2013-07-12 | Release date: | 2013-08-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell(Cambridge,Mass.), 154, 2013
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4ME7
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4MDX
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136D
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135D
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1PIK
| ESPERAMICIN A1-DNA COMPLEX, NMR, 4 STRUCTURES | Descriptor: | 2,4-dideoxy-3-O-methyl-4-(propan-2-ylamino)-alpha-L-threo-pentopyranose-(1-2)-4-amino-4,6-dideoxy-beta-D-glucopyranose, 2,6-dideoxy-4-S-methyl-4-thio-beta-D-ribo-hexopyranose, 2-deoxy-alpha-L-fucopyranose, ... | Authors: | Kumar, R.A, Ikemoto, N, Patel, D.J. | Deposit date: | 1996-12-11 | Release date: | 1997-03-12 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Esperamicin A1-DNA Complex J.Mol.Biol., 265, 1997
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5IX2
| Crystal structure of mouse Morc3 ATPase-CW cassette in complex with AMPPNP and unmodified H3 peptide | Descriptor: | MAGNESIUM ION, MORC family CW-type zinc finger protein 3, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Li, S, Du, J, Patel, D.J. | Deposit date: | 2016-03-23 | Release date: | 2016-08-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin Proc.Natl.Acad.Sci.USA, 113, 2016
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