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7Y86
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CcpS mutant
分子名称: UPF0297 protein A7J08_00425
著者Tang, J.S, Ran, T.T, Wang, W.W, Fan, H.J.
登録日2022-06-22
公開日2023-05-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A link between STK signalling and capsular polysaccharide synthesis in Streptococcus suis.
Nat Commun, 14, 2023
7Y8Z
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CcpS
分子名称: UPF0297 protein A7J08_00425
著者Tang, J.S, Ran, T.T, Wang, W.W, Fan, H.J.
登録日2022-06-24
公開日2023-05-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A link between STK signalling and capsular polysaccharide synthesis in Streptococcus suis.
Nat Commun, 14, 2023
6KUZ
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BU of 6kuz by Molmil
E.coli beta-galactosidase (E537Q) in complex with fluorescent probe KSL01
分子名称: 3-(1,3-benzothiazol-2-yl)-2-[[4-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]methoxy]-5-methyl-benzaldehyde, Beta-galactosidase, DIMETHYL SULFOXIDE, ...
著者Chen, X, Hu, Y.L, Li, X.K, Guo, Y, Li, J.
登録日2019-09-03
公開日2020-07-08
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献First-generation species-selective chemical probes for fluorescence imaging of human senescence-associated beta-galactosidase.
Chem Sci, 11, 2020
6MD4
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BU of 6md4 by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Rosiglitazone and Oleic acid
分子名称: 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), OLEIC ACID, ...
著者Shang, J, Kojetin, D.J.
登録日2018-09-03
公開日2019-01-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma.
Elife, 7, 2018
6MD1
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BU of 6md1 by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with GW9662 and Oleic acid
分子名称: 2-chloro-5-nitro-N-phenylbenzamide, OLEIC ACID, Peroxisome proliferator-activated receptor gamma
著者Shang, J, Kojetin, D.J.
登録日2018-09-03
公開日2019-01-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma.
Elife, 7, 2018
6MCZ
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Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Arachidonic Acid
分子名称: ARACHIDONIC ACID, Peroxisome proliferator-activated receptor gamma
著者Shang, J, Kojetin, D.J.
登録日2018-09-03
公開日2019-01-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma.
Elife, 7, 2018
6MD2
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BU of 6md2 by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with GW9662 and Arachidonic acid
分子名称: 2-chloro-5-nitro-N-phenylbenzamide, ARACHIDONIC ACID, Peroxisome proliferator-activated receptor gamma
著者Shang, J, Kojetin, D.J.
登録日2018-09-03
公開日2019-01-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma.
Elife, 7, 2018
6MD0
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BU of 6md0 by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Oleic Acid
分子名称: OLEIC ACID, Peroxisome proliferator-activated receptor gamma
著者Shang, J, Kojetin, D.J.
登録日2018-09-03
公開日2019-01-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma.
Elife, 7, 2018
6NR0
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BU of 6nr0 by Molmil
SIRT2(56-356) with covalent intermediate between mechanism-based inhibitor Glucose-TM-1beta and 1'-SH ADP-ribose
分子名称: GLYCEROL, NAD-dependent protein deacetylase sirtuin-2, N~2~-[3-(2-hydroxyethoxy)propanoyl]-N-phenyl-N~6~-tetradecanethioyl-L-lysinamide, ...
著者Price, I.R, Hong, J.
登録日2019-01-22
公開日2020-01-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献A Glycoconjugated SIRT2 Inhibitor with Aqueous Solubility Allows Structure-Based Design of SIRT2 Inhibitors.
Acs Chem.Biol., 14, 2019
7EU8
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BU of 7eu8 by Molmil
Structure of the human GluN1-GluN2B NMDA receptor in complex with S-ketamine,glycine and glutamate
分子名称: (2~{S})-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者Zhang, T, Zhang, Y, Zhu, S.
登録日2021-05-16
公開日2021-07-28
最終更新日2022-10-26
実験手法ELECTRON MICROSCOPY (4.07 Å)
主引用文献Structural basis of ketamine action on human NMDA receptors.
Nature, 596, 2021
7EU7
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BU of 7eu7 by Molmil
Structure of the human GluN1-GluN2A NMDA receptor in complex with S-ketamine, glycine and glutamate
分子名称: (2~{S})-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者Zhang, Y, Zhang, T, Zhu, S.
登録日2021-05-16
公開日2021-08-04
最終更新日2022-10-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of ketamine action on human NMDA receptors.
Nature, 596, 2021
8GIA
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BU of 8gia by Molmil
Crystal structure of SARS-CoV-2 (Covid-19) Nsp3 macrodomain in complex with TFMU-ADPr
分子名称: Non-structural protein 3, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5R)-3,4-dihydroxy-5-{[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]oxy}oxolan-2-yl]methyl dihydrogen diphosphate
著者Wallace, S.D, Bagde, S.R, Fromme, J.C.
登録日2023-03-13
公開日2023-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV-2 Macrodomain.
Acs Chem.Biol., 18, 2023
8JNR
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BU of 8jnr by Molmil
Crystal structure of human ALKBH3 bound to 3mC containing ssDNA through distal crosslink
分子名称: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, DNA, MANGANESE (II) ION, ...
著者Zhang, L.
登録日2023-06-06
公開日2024-01-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.66 Å)
主引用文献The Molecular Basis of Human ALKBH3 Mediated RNA N 1 -methyladenosine (m 1 A) Demethylation.
Angew.Chem.Int.Ed.Engl., 63, 2024
8JNK
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Crystal structure of human ALKBH3 bound to ssDNA through active site crosslink
分子名称: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, DNA, MANGANESE (II) ION, ...
著者Zhang, L.
登録日2023-06-06
公開日2024-01-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献The Molecular Basis of Human ALKBH3 Mediated RNA N 1 -methyladenosine (m 1 A) Demethylation.
Angew.Chem.Int.Ed.Engl., 63, 2024
8JKK
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Crystal Structure of the dioxygenase CcTet from Coprinopsis cinerea bound to 12bp 5-methylcytosine (5mC) containing duplex DNA
分子名称: 2OGFeDO JBP1/TET oxygenase domain-containing protein, DNA (5'-D(P*CP*GP*AP*TP*CP*(5CM)P*GP*CP*TP*AP*CP*G)-3'), DNA (5'-D(P*CP*GP*TP*AP*GP*CP*TP*GP*AP*TP*CP*G)-3'), ...
著者Zhang, L, Zhang, L.
登録日2023-06-01
公開日2024-03-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular basis of an atypical dsDNA 5mC/6mA bifunctional dioxygenase CcTet from Coprinopsis cinerea in catalyzing dsDNA 5mC demethylation.
Nucleic Acids Res., 52, 2024
6AVI
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BU of 6avi by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with GW9662 and Nonanoic acid
分子名称: 2-chloro-5-nitro-N-phenylbenzamide, Peroxisome proliferator-activated receptor gamma, nonanoic acid
著者Shang, J, Kojetin, D.J.
登録日2017-09-02
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma.
Elife, 7, 2018
6AUG
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BU of 6aug by Molmil
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with SR16832
分子名称: 2-chloro-N-(6-methoxyquinolin-4-yl)-5-nitrobenzamide, Peroxisome proliferator-activated receptor gamma, nonanoic acid
著者Shang, J, Kojetin, D.J.
登録日2017-08-31
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma.
Elife, 7, 2018
7WUJ
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BU of 7wuj by Molmil
Tethered peptide activation mechanism of adhesion GPCRs ADGRG2 and ADGRG4
分子名称: Adhesion G-protein coupled receptor G4,Uncharacterized protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Guo, S.C, Huang, S.M, He, Q.T, Xiao, P, Sun, J.P, Yu, X.
登録日2022-02-08
公開日2022-04-27
最終更新日2022-05-11
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4.
Nature, 604, 2022
7WUI
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Tethered peptide activation mechanism of adhesion GPCRs ADGRG2 and ADGRG4
分子名称: Adhesion G-protein coupled receptor G2,mCherry, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Guo, S.C, He, Q.T, Xiao, P, Sun, J.P, Yu, X.
登録日2022-02-08
公開日2022-04-27
最終更新日2022-05-11
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4.
Nature, 604, 2022
7WUQ
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Tethered peptide activation mechanism of adhesion GPCRs ADGRG2 and ADGRG4
分子名称: Adhesion G-protein coupled receptor G2,mCherry, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者He, Q.T, Guo, S.C, Xiao, P, Sun, J.P, Yu, X, Gou, L, Kong, L.L, Zhang, L.
登録日2022-02-09
公開日2022-04-27
最終更新日2022-05-11
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4.
Nature, 604, 2022
4ATL
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BU of 4atl by Molmil
Crystal structure of Raucaffricine glucosidase in complex with Glucose
分子名称: RAUCAFFRICINE-O-BETA-D-GLUCOSIDASE, beta-D-glucopyranose
著者Xia, L, Rajendran, C, Ruppert, M, Panjikar, S, Wang, M, Stoeckigt, J.
登録日2012-05-08
公開日2013-01-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献High Speed X-Ray Analysis of Plant Enzymes at Room Temperature
Phytochemistry, 91, 2013
4ATD
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Crystal structure of native Raucaffricine glucosidase
分子名称: RAUCAFFRICINE-O-BETA-D-GLUCOSIDASE, SULFATE ION
著者Xia, L, Rajendran, C, Ruppert, M, Panjikar, S, Wang, M, Stoeckigt, J.
登録日2012-05-05
公開日2013-01-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献High Speed X-Ray Analysis of Plant Enzymes at Room Temperature
Phytochemistry, 91, 2013
6KLY
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Crystal structure of the type III effector XopAI from Xanthomonas axonopodis pv. citri in space group P43212
分子名称: Type III effector XopAI
著者Liu, J.-H, Wu, J.E, Lin, H, Chiu, S.W, Yang, J.Y.
登録日2019-07-30
公開日2019-08-21
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Crystal Structure-Based Exploration of Arginine-Containing Peptide Binding in the ADP-Ribosyltransferase Domain of the Type III Effector XopAI Protein.
Int J Mol Sci, 20, 2019

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