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2KWF
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BU of 2kwf by Molmil
The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1
分子名称: CREB-binding protein, Transcription factor 4
著者Denis, C.M, Chitayat, S, Plevin, M.J, Liu, S, Spencer, H.L, Ikura, M, LeBrun, D.P, Smith, S.P.
登録日2010-04-08
公開日2011-07-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates leukemia induction by E2A-PBX1
To be Published
2L5Y
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BU of 2l5y by Molmil
NMR structure of calcium-loaded STIM2 EF-SAM.
分子名称: CALCIUM ION, Stromal interaction molecule 2
著者Zheng, L, Stathopulos, P.B, Ikura, M.
登録日2010-11-09
公開日2011-01-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry.
Proc.Natl.Acad.Sci.USA, 108, 2011
2LQH
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BU of 2lqh by Molmil
NMR structure of FOXO3a transactivation domains (CR2C-CR3) in complex with CBP KIX domain (2b3l conformation)
分子名称: CREB-binding protein, Forkhead box O3
著者Wang, F, Marshall, C.B, Yamamoto, K, Li, G.B, Gasmi-Seabrook, G.M.C, Okada, H, Mak, T.W, Ikura, M.
登録日2012-03-06
公開日2012-05-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment.
Proc.Natl.Acad.Sci.USA, 109, 2012
2LQI
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BU of 2lqi by Molmil
NMR structure of FOXO3a transactivation domains (CR2C-CR3) in complex with CBP KIX domain (2l3b conformation)
分子名称: CREB-binding protein, Forkhead box O3
著者Wang, F, Marshall, C.B, Yamamoto, K, Li, G.B, Gasmi-Seabrook, G.M.C, Okada, H, Mak, T.W, Ikura, M.
登録日2012-03-06
公開日2012-05-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment.
Proc.Natl.Acad.Sci.USA, 109, 2012
2MC2
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BU of 2mc2 by Molmil
X-ray crystallography-solution NMR hybrid structure of mouse RyR2 domain A
分子名称: Ryanodine receptor 2
著者Amador, F, Stathopulos, P, Seabrook, G, Ikura, M.
登録日2013-08-13
公開日2013-09-11
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic alpha-Helix That Transitions to a beta-Strand in a Mutant Linked with a Heritable Cardiomyopathy.
J.Mol.Biol., 425, 2013
5Y0C
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BU of 5y0c by Molmil
Crystal Structure of the human nucleosome at 2.09 angstrom resolution
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Kurumizaka, H, Arimura, Y, Fujita, R, Noda, M.
登録日2017-07-16
公開日2018-07-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.087 Å)
主引用文献Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome.
Nucleic Acids Res., 46, 2018
5Y0D
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BU of 5y0d by Molmil
Crystal Structure of the human nucleosome containing the H2B E76K mutant
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ...
著者Kurumizaka, H, Arimura, Y, Fujita, R, Noda, M.
登録日2017-07-16
公開日2018-07-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome.
Nucleic Acids Res., 46, 2018
5Z30
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BU of 5z30 by Molmil
The crystal structure of the nucleosome containing a cancer-associated histone H2A.Z R80C mutant
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A.Z, ...
著者Horikoshi, N, Arimura, Y, Kurumizaka, H.
登録日2018-01-05
公開日2018-07-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome.
Nucleic Acids Res., 46, 2018
7KMR
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BU of 7kmr by Molmil
Crystal structure analysis of human KRAS mutant
分子名称: GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas
著者Seo, H.-S, Dhe-Paganon, S.
登録日2020-11-03
公開日2021-11-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Regulation of GTPase function by autophosphorylation.
Mol.Cell, 82, 2022
5E95
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BU of 5e95 by Molmil
Crystal Structure of Mb(NS1)/H-Ras Complex
分子名称: GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Eguchi, R.R, Sha, F, Gupta, A, Koide, A, Koide, S.
登録日2015-10-14
公開日2016-11-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.402 Å)
主引用文献Inhibition of RAS function through targeting an allosteric regulatory site.
Nat. Chem. Biol., 13, 2017
3RQR
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BU of 3rqr by Molmil
Crystal structure of the RYR domain of the rabbit ryanodine receptor
分子名称: (UNK)(UNK)(UNK)(UNK), Ryanodine receptor 1
著者Nair, U.B, Li, W, Dong, A, Walker, J.R, Gramolini, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2011-04-28
公開日2011-06-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Structural determination of the phosphorylation domain of the ryanodine receptor.
Febs J., 279, 2012
7JIF
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BU of 7jif by Molmil
HRAS A59T GppNHp
分子名称: GLYCEROL, GTPase HRas, MAGNESIUM ION, ...
著者Johnson, C.W, Haigis, K.M.
登録日2020-07-23
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.757 Å)
主引用文献Regulation of GTPase function by autophosphorylation.
Mol.Cell, 82, 2022
7JII
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BU of 7jii by Molmil
HRAS A59E GDP
分子名称: CALCIUM ION, GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Johnson, C.W, Haigis, K.M.
登録日2020-07-23
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.532 Å)
主引用文献Regulation of GTPase function by autophosphorylation.
Mol.Cell, 82, 2022
7JIG
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BU of 7jig by Molmil
HRAS A59T GppNHp crystal 2
分子名称: GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Johnson, C.W, Haigis, K.M.
登録日2020-07-23
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.322 Å)
主引用文献Regulation of GTPase function by autophosphorylation.
Mol.Cell, 82, 2022
7JIH
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BU of 7jih by Molmil
HRAS A59E GppNHp
分子名称: GLYCEROL, GTPase HRas, MAGNESIUM ION, ...
著者Johnson, C.W, Haigis, K.M.
登録日2020-07-23
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.989 Å)
主引用文献Regulation of GTPase function by autophosphorylation.
Mol.Cell, 82, 2022
4KEJ
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BU of 4kej by Molmil
Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant R169Q
分子名称: Ryanodine receptor 2
著者Kimlicka, L, Van Petegem, F.
登録日2013-04-25
公開日2013-09-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.553 Å)
主引用文献Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic alpha-Helix That Transitions to a beta-Strand in a Mutant Linked with a Heritable Cardiomyopathy.
J.Mol.Biol., 425, 2013
4KEI
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BU of 4kei by Molmil
Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S
分子名称: Ryanodine receptor 2
著者Kimlicka, L, Van Petegem, F.
登録日2013-04-25
公開日2013-09-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.406 Å)
主引用文献Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic alpha-Helix That Transitions to a beta-Strand in a Mutant Linked with a Heritable Cardiomyopathy.
J.Mol.Biol., 425, 2013
4KEK
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BU of 4kek by Molmil
Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant R176Q
分子名称: Ryanodine receptor 2, SULFATE ION
著者Kimlicka, L, Van Petegem, F.
登録日2013-04-25
公開日2013-09-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.146 Å)
主引用文献Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic alpha-Helix That Transitions to a beta-Strand in a Mutant Linked with a Heritable Cardiomyopathy.
J.Mol.Biol., 425, 2013
2Z1O
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BU of 2z1o by Molmil
Crystal structure of a photoswitchable GFP-like protein Dronpa in the bright-state
分子名称: Fluorescent protein Dronpa
著者Kikuchi, A, Jeyakanthan, J, Taka, J, Shiro, Y, Mizuno, H, Miyawaki, A.
登録日2007-05-10
公開日2008-05-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Light-dependent regulation of structural flexibility in a photochromic fluorescent protein
Proc.Natl.Acad.Sci.Usa, 105, 2008
2Z6X
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BU of 2z6x by Molmil
Crystal structure of 22G, the wild-type protein of the photoswitchable GFP-like protein Dronpa
分子名称: photochromic protein Dronpa
著者Kikuchi, A, Jeyakanthan, J, Taka, J, Shiro, Y, Mizuno, H, Miyawaki, A.
登録日2007-08-09
公開日2008-07-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Light-dependent regulation of structural flexibility in a photochromic fluorescent protein.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2Z6Y
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BU of 2z6y by Molmil
Crystal structure of a photoswitchable GFP-like protein Dronpa in the bright-state
分子名称: Fluorescent protein Dronpa
著者Kikuchi, A, Jeyakanthan, J, Taka, J, Shiro, Y, Mizuno, H, Miyawaki, A.
登録日2007-08-09
公開日2008-07-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Light-dependent regulation of structural flexibility in a photochromic fluorescent protein.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2Z6Z
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BU of 2z6z by Molmil
Crystal structure of a photoswitchable GFP-like protein Dronpa in the bright-state
分子名称: Fluorescent protein Dronpa
著者Kikuchi, A, Jeyakanthan, J, Taka, J, Shiro, Y, Mizuno, H, Miyawaki, A.
登録日2007-08-09
公開日2008-07-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Light-dependent regulation of structural flexibility in a photochromic fluorescent protein.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1NPS
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BU of 1nps by Molmil
CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF PROTEIN S
分子名称: CALCIUM ION, DEVELOPMENT-SPECIFIC PROTEIN S
著者Wenk, M, Baumgartner, R, Mayer, E.M, Huber, R, Holak, T.A, Jaenicke, R.
登録日1999-02-01
公開日2000-02-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The domains of protein S from Myxococcus xanthus: structure, stability and interactions.
J.Mol.Biol., 286, 1999
1C9B
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BU of 1c9b by Molmil
CRYSTAL STRUCTURE OF A HUMAN TBP CORE DOMAIN-HUMAN TFIIB CORE DOMAIN COMPLEX BOUND TO AN EXTENDED, MODIFIED ADENOVIRAL MAJOR LATE PROMOTER (ADMLP)
分子名称: ADMLP TATA-BOX DNA CONTAINING IIB RECOGNITION ELEMENT, GENERAL TRANSCRIPTION FACTOR IIB, TATA BOX BINDING PROTEIN
著者Tsai, F.T.F, Sigler, P.B.
登録日1999-08-01
公開日2000-01-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural basis of preinitiation complex assembly on human pol II promoters.
EMBO J., 19, 2000
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