5Z30
The crystal structure of the nucleosome containing a cancer-associated histone H2A.Z R80C mutant
Summary for 5Z30
Entry DOI | 10.2210/pdb5z30/pdb |
Descriptor | Histone H3.1, Histone H4, Histone H2A.Z, ... (8 entities in total) |
Functional Keywords | dna binding, nucleus, chromatin formation, histone fold, histone, nucleosome, chromatin, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 10 |
Total formula weight | 201630.31 |
Authors | Horikoshi, N.,Arimura, Y.,Kurumizaka, H. (deposition date: 2018-01-05, release date: 2018-07-18, Last modification date: 2023-11-22) |
Primary citation | Arimura, Y.,Ikura, M.,Fujita, R.,Noda, M.,Kobayashi, W.,Horikoshi, N.,Sun, J.,Shi, L.,Kusakabe, M.,Harata, M.,Ohkawa, Y.,Tashiro, S.,Kimura, H.,Ikura, T.,Kurumizaka, H. Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome. Nucleic Acids Res., 46:10007-10018, 2018 Cited by PubMed: 30053102DOI: 10.1093/nar/gky661 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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