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2MC2

X-ray crystallography-solution NMR hybrid structure of mouse RyR2 domain A

Summary for 2MC2
Entry DOI10.2210/pdb2mc2/pdb
Related3IM5 3QR5 4KEI 4KEJ 4KEK
NMR InformationBMRB: 19425
DescriptorRyanodine receptor 2 (1 entity in total)
Functional Keywordsryanodine receptor, type ii, alpha2 helix, metal transport
Biological sourceMus musculus (mouse)
Cellular locationSarcoplasmic reticulum membrane; Multi-pass membrane protein (Probable): E9Q401
Total number of polymer chains1
Total formula weight24169.16
Authors
Amador, F.,Stathopulos, P.,Seabrook, G.,Ikura, M. (deposition date: 2013-08-13, release date: 2013-09-11, Last modification date: 2023-06-14)
Primary citationAmador, F.J.,Kimlicka, L.,Stathopulos, P.B.,Gasmi-Seabrook, G.M.,Maclennan, D.H.,Van Petegem, F.,Ikura, M.
Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic alpha-Helix That Transitions to a beta-Strand in a Mutant Linked with a Heritable Cardiomyopathy.
J.Mol.Biol., 425:4034-4046, 2013
Cited by
PubMed: 23978697
DOI: 10.1016/j.jmb.2013.08.015
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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