3JRR
| Crystal structure of the ligand binding suppressor domain of type 3 inositol 1,4,5-trisphosphate receptor | Descriptor: | Inositol 1,4,5-trisphosphate receptor type 3 | Authors: | Chan, J, Ishiyama, N, Ikura, M. | Deposit date: | 2009-09-08 | Release date: | 2010-09-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A 1.9 angstrom crystal structure of the suppressor domain of type 3 inositol 1,4,5-trisphosphate receptor To be Published
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3L6Y
| Crystal structure of p120 catenin in complex with E-cadherin | Descriptor: | Catenin delta-1, E-cadherin | Authors: | Ishiyama, N, Lee, S.-H, Liu, S, Li, G.-Y, Smith, M.J, Reichardt, L.F, Ikura, M. | Deposit date: | 2009-12-27 | Release date: | 2010-04-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion. Cell(Cambridge,Mass.), 141, 2010
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3L6X
| Crystal structure of p120 catenin in complex with E-cadherin | Descriptor: | Catenin delta-1, E-cadherin, SULFATE ION | Authors: | Ishiyama, N, Lee, S.-H, Liu, S, Li, G.-Y, Smith, M.J, Reichardt, L.F, Ikura, M. | Deposit date: | 2009-12-27 | Release date: | 2010-04-21 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion. Cell(Cambridge,Mass.), 141, 2010
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1SUH
| AMINO-TERMINAL DOMAIN OF EPITHELIAL CADHERIN IN THE CALCIUM BOUND STATE, NMR, 20 STRUCTURES | Descriptor: | EPITHELIAL CADHERIN | Authors: | Overduin, M, Tong, K.I, Kay, C.M, Ikura, M. | Deposit date: | 1996-01-30 | Release date: | 1996-07-11 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | 1H, 15N and 13C resonance assignments and monomeric structure of the amino-terminal extracellular domain of epithelial cadherin. J.Biomol.NMR, 7, 1996
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1PRR
| NMR-DERIVED THREE-DIMENSIONAL SOLUTION STRUCTURE OF PROTEIN S COMPLEXED WITH CALCIUM | Descriptor: | CALCIUM ION, DEVELOPMENT-SPECIFIC PROTEIN S | Authors: | Bagby, S, Harvey, T.S, Eagle, S.G, Inouye, S, Ikura, M. | Deposit date: | 1994-03-25 | Release date: | 1994-08-31 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | NMR-derived three-dimensional solution structure of protein S complexed with calcium. Structure, 2, 1994
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1PRS
| NMR-DERIVED THREE-DIMENSIONAL SOLUTION STRUCTURE OF PROTEIN S COMPLEXED WITH CALCIUM | Descriptor: | CALCIUM ION, DEVELOPMENT-SPECIFIC PROTEIN S | Authors: | Bagby, S, Harvey, T.S, Eagle, S.G, Inouye, S, Ikura, M. | Deposit date: | 1994-03-25 | Release date: | 1994-08-31 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | NMR-derived three-dimensional solution structure of protein S complexed with calcium. Structure, 2, 1994
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4O25
| Structure of Wild Type Mus musculus Rheb bound to GTP | Descriptor: | GTP-binding protein Rheb, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | Authors: | Mazhab-Jafari, M.T, Marshall, C.B, Ho, J, Ishiyama, N, Stambolic, V, Ikura, M. | Deposit date: | 2013-12-16 | Release date: | 2014-03-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR). J.Biol.Chem., 289, 2014
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4O2L
| Structure of Mus musculus Rheb G63A mutant bound to GTP | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, GTP-binding protein Rheb, ... | Authors: | Mazhab-Jafari, M.T, Marshall, C.B, Ho, J, Ishiyama, N, Stambolic, V, Ikura, M. | Deposit date: | 2013-12-17 | Release date: | 2014-03-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR). J.Biol.Chem., 289, 2014
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4O2R
| Structure of Mus musculus Rheb G63V mutant bound to GDP | Descriptor: | GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Mazhab-Jafari, M.T, Marshall, C.B, Ho, J, Ishiyama, N, Stambolic, V, Ikura, M. | Deposit date: | 2013-12-17 | Release date: | 2014-03-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR). J.Biol.Chem., 289, 2014
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6AMB
| Crystal Structure of the Afadin RA1 domain in complex with HRAS | Descriptor: | Afadin, GTPase HRas, MAGNESIUM ION, ... | Authors: | Smith, M.J, Ishiyama, N, Ikura, M. | Deposit date: | 2017-08-09 | Release date: | 2017-11-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Evolution of AF6-RAS association and its implications in mixed-lineage leukemia. Nat Commun, 8, 2017
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2GW3
| Crystal structure of stony coral fluorescent protein Kaede, green form | Descriptor: | Kaede, NICKEL (II) ION | Authors: | Hayashi, I, Mizuno, H, Miyawaki, A, Ikura, M. | Deposit date: | 2006-05-03 | Release date: | 2007-05-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystallographic evidence for water-assisted photo-induced peptide cleavage in the stony coral fluorescent protein Kaede. J.Mol.Biol., 372, 2007
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2GW4
| Crystal structure of stony coral fluorescent protein Kaede, red form | Descriptor: | Kaede, NICKEL (II) ION | Authors: | Hayashi, I, Mizuno, H, Miyawako, A, Ikura, M. | Deposit date: | 2006-05-03 | Release date: | 2007-05-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystallographic evidence for water-assisted photo-induced peptide cleavage in the stony coral fluorescent protein Kaede. J.Mol.Biol., 372, 2007
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6CC9
| NMR data-driven model of GTPase KRas-GMPPNP:Cmpd2 complex tethered to a nanodisc | Descriptor: | (2R,4S)-4-[(5-bromo-1H-indole-3-carbonyl)amino]-2-[(4-chlorophenyl)methyl]piperidin-1-ium, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, ... | Authors: | Fang, Z, Marshall, C.B, Nishikawa, T, Gossert, A.D, Jansen, J.M, Jahnke, W, Ikura, M. | Deposit date: | 2018-02-06 | Release date: | 2018-09-05 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site. Cell Chem Biol, 25, 2018
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1JOY
| SOLUTION STRUCTURE OF THE HOMODIMERIC DOMAIN OF ENVZ FROM ESCHERICHIA COLI BY MULTI-DIMENSIONAL NMR. | Descriptor: | PROTEIN (ENVZ_ECOLI) | Authors: | Tomomori, C, Tanaka, T, Dutta, R, Park, H, Saha, S.K, Zhu, Y, Ishima, R, Liu, D, Tong, K.I, Kurokawa, H, Qian, H, Inouye, M, Ikura, M. | Deposit date: | 1998-12-28 | Release date: | 2000-01-12 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of the homodimeric core domain of Escherichia coli histidine kinase EnvZ. Nat.Struct.Biol., 6, 1999
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6CCX
| NMR data-driven model of GTPase KRas-GMPPNP:Cmpd2 complex tethered to a nanodisc | Descriptor: | (2R,4S)-4-[(5-bromo-1H-indole-3-carbonyl)amino]-2-[(4-chlorophenyl)methyl]piperidin-1-ium, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, ... | Authors: | Fang, Z, Marshall, C.B, Nishikawa, T, Gossert, A.D, Jansen, J.M, Jahnke, W, Ikura, M. | Deposit date: | 2018-02-07 | Release date: | 2018-09-05 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site. Cell Chem Biol, 25, 2018
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6CCH
| NMR data-driven model of GTPase KRas-GMPPNP tethered to a nanodisc (E3 state) | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... | Authors: | Fang, Z, Marshall, C.B, Nishikawa, T, Gossert, A.D, Jansen, J.M, Jahnke, W, Ikura, M. | Deposit date: | 2018-02-07 | Release date: | 2018-08-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Inhibition of K-RAS4B by a Unique Mechanism of Action: Stabilizing Membrane-Dependent Occlusion of the Effector-Binding Site. Cell Chem Biol, 25, 2018
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6DUW
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6DV1
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6DUY
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1N4K
| Crystal structure of the inositol 1,4,5-trisphosphate receptor binding core in complex with IP3 | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 1 | Authors: | Bosanac, I, Alattia, J.R, Mal, T.K, Chan, J, Talarico, S, Tong, F.K, Tong, K.I, Yoshikawa, F, Furuichi, T, Iwai, M, Michikawa, T, Mikoshiba, K, Ikura, M. | Deposit date: | 2002-10-31 | Release date: | 2002-12-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the inositol 1,4,5-trisphosphate receptor
binding core in complex with its ligand. Nature, 420, 2002
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1MUX
| SOLUTION NMR STRUCTURE OF CALMODULIN/W-7 COMPLEX: THE BASIS OF DIVERSITY IN MOLECULAR RECOGNITION, 30 STRUCTURES | Descriptor: | CALCIUM ION, CALMODULIN, N-(6-AMINOHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE | Authors: | Osawa, M, Swindells, M.B, Tanikawa, J, Tanaka, T, Mase, T, Furuya, T, Ikura, M. | Deposit date: | 1997-09-06 | Release date: | 1998-10-14 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of calmodulin-W-7 complex: the basis of diversity in molecular recognition. J.Mol.Biol., 276, 1998
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1TFB
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1IKU
| myristoylated recoverin in the calcium-free state, NMR, 22 structures | Descriptor: | MYRISTIC ACID, RECOVERIN | Authors: | Tanaka, T, Ames, J.B, Harvey, T.S, Stryer, L, Ikura, M. | Deposit date: | 1996-01-18 | Release date: | 1996-07-11 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Sequestration of the membrane-targeting myristoyl group of recoverin in the calcium-free state. Nature, 376, 1995
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1XZZ
| Crystal structure of the ligand binding suppressor domain of type 1 inositol 1,4,5-trisphosphate receptor | Descriptor: | GLYCEROL, Inositol 1,4,5-trisphosphate receptor type 1 | Authors: | Bosanac, I, Yamazaki, H, Matsu-ura, T, Michikawa, T, Mikoshiba, K, Ikura, M. | Deposit date: | 2004-11-13 | Release date: | 2005-01-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the ligand binding suppressor domain of type 1 inositol 1,4,5-trisphosphate receptor. Mol.Cell, 17, 2005
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1RO4
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