1N4K

Crystal structure of the inositol 1,4,5-trisphosphate receptor binding core in complex with IP3

Summary for 1N4K

Entry DOI	10.2210/pdb1n4k/pdb
Descriptor	Inositol 1,4,5-trisphosphate receptor type 1, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE (3 entities in total)
Functional Keywords	ip3 receptor, ip3-binding core, calcium channel, protein-ligand complex, b-trefoil fold, armadillo-like fold, membrane protein
Biological source	Mus musculus (house mouse)
Cellular location	Endoplasmic reticulum membrane; Multi-pass membrane protein: P11881
Total number of polymer chains	1
Total formula weight	44023.37
Authors	Bosanac, I.,Alattia, J.R.,Mal, T.K.,Chan, J.,Talarico, S.,Tong, F.K.,Tong, K.I.,Yoshikawa, F.,Furuichi, T.,Iwai, M.,Michikawa, T.,Mikoshiba, K.,Ikura, M. (deposition date: 2002-10-31, release date: 2002-12-25, Last modification date: 2024-02-14)
Primary citation	Bosanac, I.,Alattia, J.R.,Mal, T.K.,Chan, J.,Talarico, S.,Tong, F.K.,Tong, K.I.,Yoshikawa, F.,Furuichi, T.,Iwai, M.,Michikawa, T.,Mikoshiba, K.,Ikura, M. Structure of the inositol 1,4,5-trisphosphate receptor binding core in complex with its ligand. Nature, 420:696-700, 2002 Cited by PubMed: 12442173 DOI: 10.1038/nature01268 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation