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1L8L
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BU of 1l8l by Molmil
Molecular basis for the local confomational rearrangement of human phosphoserine phosphatase
Descriptor: D-2-AMINO-3-PHOSPHONO-PROPIONIC ACID, L-3-phosphoserine phosphatase
Authors:Kim, H.Y, Heo, Y.S, Kim, J.H, Park, M.H, Moon, J, Park, S.Y, Lee, T.G, Jeon, Y.H, Ro, S, Hwang, K.Y.
Deposit date:2002-03-21
Release date:2003-04-01
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase.
J.Biol.Chem., 277, 2002
7DHA
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BU of 7dha by Molmil
crystal structure of CD38 in complex with daratumumab
Descriptor: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, Heavy Chain, Light chain
Authors:Lee, H.T, Heo, Y.S.
Deposit date:2020-11-13
Release date:2021-09-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of CD38 in complex with daratumumab, a first-in-class anti-CD38 antibody drug for treating multiple myeloma.
Biochem.Biophys.Res.Commun., 536, 2021
7WJ5
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BU of 7wj5 by Molmil
Cryo-EM structure of human somatostatin receptor 2 complex with its agonist somatostatin delineates the ligand binding specificity
Descriptor: Gai1 antibody (scfv16), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Heo, Y.S, Yoon, E.J, Jeon, Y.E, Yun, J.-H, Ishimoto, N, Woo, H, Park, S.Y, Song, J, Lee, W.T.
Deposit date:2022-01-05
Release date:2022-07-13
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Cryo-EM structure of the human somatostatin receptor 2 complex with its agonist somatostatin delineates the ligand-binding specificity.
Elife, 11, 2022
5Y9J
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BU of 5y9j by Molmil
BAFF in complex with belimumab
Descriptor: Tumor necrosis factor ligand superfamily member 13B, belibumab light chain, belimumab heavy chain
Authors:Heo, Y.-S, Shin, W.
Deposit date:2017-08-25
Release date:2018-02-21
Last modified:2019-09-04
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:BAFF-neutralizing interaction of belimumab related to its therapeutic efficacy for treating systemic lupus erythematosus.
Nat Commun, 9, 2018
5Y9K
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BU of 5y9k by Molmil
Structure of the belimumab Fab fragment
Descriptor: belimumab heavy chain, belimumab light chain
Authors:Heo, Y.-S, Shin, W.
Deposit date:2017-08-25
Release date:2018-02-21
Last modified:2019-09-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:BAFF-neutralizing interaction of belimumab related to its therapeutic efficacy for treating systemic lupus erythematosus.
Nat Commun, 9, 2018
7EOW
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BU of 7eow by Molmil
High-resolution structure of vWF A1 domain in complex with caplacizumab, the first nanobody-based medicine
Descriptor: caplacizumab, von Willebrand factor
Authors:Lee, H.T, Heo, Y.-S.
Deposit date:2021-04-23
Release date:2021-07-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:High-resolution structure of the vWF A1 domain in complex with caplacizumab, the first nanobody-based medicine for treating acquired TTP.
Biochem.Biophys.Res.Commun., 567, 2021
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