4OO2
| Streptomyces globisporus C-1027 FAD dependent (S)-3-chloro-β-tyrosine-S-SgcC2 C-5 hydroxylase SgcC apo form | 分子名称: | CALCIUM ION, Chlorophenol-4-monooxygenase, GLYCEROL | 著者 | Cao, H, Xu, W, Bingman, C.A, Lohman, J.R, Yennamalli, R, Shen, B, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2014-01-29 | 公開日 | 2014-02-12 | 最終更新日 | 2023-03-22 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus. Biochemistry, 55, 2016
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5JXM
| Crystal Structure of Prenyltransferase PriB Apo Form | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, PriB | 著者 | Cao, H, Elshahawi, S, Benach, J, Wasserman, S.R, Morisco, L.L, Koss, J.W, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2016-05-13 | 公開日 | 2016-06-08 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Structure and specificity of a permissive bacterial C-prenyltransferase. Nat. Chem. Biol., 13, 2017
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5BP8
| ent-Copalyl diphosphate synthase from Streptomyces platensis | 分子名称: | 1,2-ETHANEDIOL, Ent-copalyl diphosphate synthase, SULFATE ION | 著者 | Osipiuk, J, Hatzos-Skintges, C, Endres, M, Babnigg, G, Rudolf, J.D, Ma, M, Chang, C.-Y, Shen, B, Joachimiak, A, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-05-27 | 公開日 | 2015-06-10 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of the ent-Copalyl Diphosphate Synthase PtmT2 from Streptomyces platensis CB00739, a Bacterial Type II Diterpene Synthase. J.Am.Chem.Soc., 138, 2016
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4K0B
| Crystal structure of S-Adenosylmethionine synthetase from Sulfolobus solfataricus complexed with SAM and PPi | 分子名称: | DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Wang, F, Hurley, K.A, Helmich, K.E, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2013-04-03 | 公開日 | 2013-05-01 | 最終更新日 | 2014-10-08 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus. Febs J., 281, 2014
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4L7I
| Crystal structure of S-Adenosylmethionine synthase from Sulfolobus solfataricus complexed with SAM and PPi | 分子名称: | DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Wang, F, Hurley, K.A, Helmich, K.E, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2013-06-13 | 公開日 | 2013-07-03 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.189 Å) | 主引用文献 | Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus. Febs J., 281, 2014
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4L2Z
| Crystal structure of S-Adenosylmethionine synthetase from Sulfolobus solfataricus complexed with SAE and PPi | 分子名称: | DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Wang, F, Hurley, K.A, Helmich, K.E, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2013-06-05 | 公開日 | 2013-06-19 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.494 Å) | 主引用文献 | Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus. Febs J., 281, 2014
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5UMY
| Crystal structure of TnmS3 in complex with tiancimycin | 分子名称: | (1aS,11S,11aR,14Z,18R)-3,8,18-trihydroxy-11a-[(1R)-1-hydroxyethyl]-7-methoxy-11,11a-dihydro-4H-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinoline-4,9(10H)-dione, Glyoxalase/bleomycin resisance protein/dioxygenase | 著者 | Chang, C.Y, Chang, C, Nocek, B, Rudolf, J.D, Joachimiak, A, Phillips Jr, G.N, SHen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG) | 登録日 | 2017-01-29 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Resistance to Enediyne Antitumor Antibiotics by Sequestration. Cell Chem Biol, 25, 2018
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4G2T
| Crystal Structure of Streptomyces sp. SF2575 glycosyltransferase SsfS6, complexed with thymidine diphosphate | 分子名称: | SsfS6, THYMIDINE-5'-DIPHOSPHATE | 著者 | Wang, F, Zhou, M, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2012-07-12 | 公開日 | 2012-07-25 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.405 Å) | 主引用文献 | Crystal structure of SsfS6, the putative C-glycosyltransferase involved in SF2575 biosynthesis. Proteins, 81, 2013
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5UMX
| Crystal structure of TnmS3 in complex with riboflavin | 分子名称: | Glyoxalase/bleomycin resisance protein/dioxygenase, RIBOFLAVIN | 著者 | Chang, C.Y, Chang, C, Nocek, B, Rudolf, J.D, Joachimiak, A, Phillips Jr, G.N, Shen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG) | 登録日 | 2017-01-29 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Resistance to Enediyne Antitumor Antibiotics by Sequestration. Cell Chem Biol, 25, 2018
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5UMW
| Crystal structure of TnmS2, an antibiotic binding protein from Streptomyces sp. CB03234 | 分子名称: | Glyoxalase/bleomycin resisance protein/dioxygenase, RIBOFLAVIN | 著者 | Chang, C.Y, Chang, C, Nocek, B, Rudolf, J.D, Joachimiak, A, Phillips Jr, G.N, Shen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG) | 登録日 | 2017-01-29 | 公開日 | 2018-07-04 | 最終更新日 | 2020-09-23 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Resistance to Enediyne Antitumor Antibiotics by Sequestration. Cell Chem Biol, 25, 2018
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4TKT
| Streptomyces platensis isomigrastatin ketosynthase domain MgsF KS6 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, AT-less polyketide synthase, CHLORIDE ION, ... | 著者 | Chang, C, Li, H, Endres, M, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2014-05-27 | 公開日 | 2014-06-11 | 最終更新日 | 2023-03-22 | 実験手法 | X-RAY DIFFRACTION (2.4289 Å) | 主引用文献 | Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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4HPV
| Crystal structure of S-Adenosylmethionine synthetase from Sulfolobus solfataricus | 分子名称: | S-adenosylmethionine synthase | 著者 | Wang, F, Hurley, K.A, Helmich, K.E, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2012-10-24 | 公開日 | 2012-11-14 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.214 Å) | 主引用文献 | Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus. Febs J., 281, 2014
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4OPE
| Streptomcyes albus JA3453 oxazolomycin ketosynthase domain OzmH KS7 | 分子名称: | NITRATE ION, NRPS/PKS | 著者 | Osipiuk, J, Mack, J, Endres, M, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2014-02-05 | 公開日 | 2014-02-19 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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4QYR
| Streptomyces platensis isomigrastatin ketosynthase domain MgsE KS3 | 分子名称: | ACETIC ACID, AT-less polyketide synthase, CHLORIDE ION, ... | 著者 | Kim, Y, Li, H, Endres, M, Babnigg, J, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2014-07-25 | 公開日 | 2014-08-20 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.902 Å) | 主引用文献 | Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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5UJP
| The crystal structure of a glyoxalase/bleomycin resistance protein from Streptomyces sp. CB03234 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Glyoxalase/bleomycin resisance protein/dioxygenase | 著者 | Tan, K, Li, H, Endres, M, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2017-01-18 | 公開日 | 2017-02-22 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | The crystal structure of a glyoxalase/bleomycin resistance protein from Streptomyces sp. CB03234 To Be Published
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4FZR
| Crystal Structure of SsfS6, Streptomyces sp. SF2575 glycosyltransferase | 分子名称: | SsfS6 | 著者 | Wang, F, Zhou, M, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2012-07-07 | 公開日 | 2012-07-25 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.397 Å) | 主引用文献 | Crystal structure of SsfS6, the putative C-glycosyltransferase involved in SF2575 biosynthesis. Proteins, 81, 2013
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5UMQ
| Crystal structure of TnmS1, an antibiotic binding protein from Streptomyces sp. CB03234 | 分子名称: | Glyoxalase/bleomycin resisance protein/dioxygenase | 著者 | Chang, C.Y, Chang, C, Nocek, B, Rudolf, J.D, Joachimiak, A, Phillips Jr, G.N, Shen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG) | 登録日 | 2017-01-29 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Resistance to Enediyne Antitumor Antibiotics by Sequestration. Cell Chem Biol, 25, 2018
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5UMP
| Crystal structure of TnmS3, an antibiotic binding protein from Streptomyces sp. CB03234 | 分子名称: | Glyoxalase/bleomycin resisance protein/dioxygenase | 著者 | Chang, C.Y, Chang, C, Nocek, B, Rudolf, J.D, Joachimiak, A, Phillips Jr, G.N, Shen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG) | 登録日 | 2017-01-29 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | 主引用文献 | Resistance to Enediyne Antitumor Antibiotics by Sequestration. Cell Chem Biol, 25, 2018
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4NEO
| Structure of BlmI, a type-II acyl-carrier-protein from Streptomyces verticillus involved in bleomycin biosynthesis | 分子名称: | 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, Peptide synthetase NRPS type II-PCP | 著者 | Cuff, M.E, Bigelow, L, Bearden, J, Babnigg, G, Bruno, C.J.P, Bingman, C.A, Yennamalli, R, Lohman, J, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG) | 登録日 | 2013-10-29 | 公開日 | 2014-01-29 | 最終更新日 | 2023-03-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The crystal structure of BlmI as a model for nonribosomal peptide synthetase peptidyl carrier proteins. Proteins, 82, 2014
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4OPF
| Streptomcyes albus JA3453 oxazolomycin ketosynthase domain OzmH KS8 | 分子名称: | NRPS/PKS | 著者 | Osipiuk, J, Bigelow, L, Endres, M, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2014-02-05 | 公開日 | 2014-02-19 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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5VPJ
| The crystal structure of a thioesteras from Actinomadura verrucosospora. | 分子名称: | CHLORIDE ION, TETRAETHYLENE GLYCOL, Thioesterase | 著者 | Tan, K, Joachimiak, G, Endres, M, Phillips Jr, G.N, Joachmiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2017-05-05 | 公開日 | 2017-07-19 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | The crystal structure of a thioesteras from Actinomadura verrucosospora. To Be Published
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4HX6
| Streptomyces globisporus C-1027 NADH:FAD oxidoreductase SgcE6 | 分子名称: | ACETATE ION, Oxidoreductase, SULFATE ION | 著者 | Tan, K, Bigelow, L, Clancy, S, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2012-11-09 | 公開日 | 2012-11-28 | 最終更新日 | 2016-12-07 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus. Biochemistry, 55, 2016
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4Q29
| Ensemble Refinement of plu4264 protein from Photorhabdus luminescens | 分子名称: | NICKEL (II) ION, SODIUM ION, plu4264 protein | 著者 | Wang, F, Michalska, K, Li, H, Jedrzejczak, R, Babnigg, G, Bingman, C.A, Yennamalli, R, Weerth, S, Miller, M.D, Thomas, M.G, Joachimiak, A, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG) | 登録日 | 2014-04-07 | 公開日 | 2014-05-07 | 最終更新日 | 2015-02-11 | 実験手法 | X-RAY DIFFRACTION (1.349 Å) | 主引用文献 | Structure of a cupin protein Plu4264 from Photorhabdus luminescens subsp. laumondii TTO1 at 1.35 angstrom resolution. Proteins, 83, 2015
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4RNL
| The crystal structure of a possible galactose mutarotase from Streptomyces platensis subsp. rosaceus | 分子名称: | GLYCEROL, PHOSPHATE ION, possible galactose mutarotase | 著者 | Tan, K, Li, H, Endres, M, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2014-10-24 | 公開日 | 2014-11-26 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The crystal structure of a possible galactose mutarotase from Streptomyces platensis subsp. rosaceus To be Published
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4QA9
| Ensemble refinement of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus. | 分子名称: | 1,2-ETHANEDIOL, Epoxide hydrolase, SULFATE ION | 著者 | Wang, F, Tan, K, Bigelow, L, Clancy, S, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J, Ma, M, Shen, B, Joachimiak, A, Phillips Jr, G.N, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2014-05-02 | 公開日 | 2014-05-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Ensemble refinement of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus. To be Published
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