4L7I

Crystal structure of S-Adenosylmethionine synthase from Sulfolobus solfataricus complexed with SAM and PPi

Summary for 4L7I

Entry DOI	10.2210/pdb4l7i/pdb
Related	4HPV 4K0B 4L2Z
Descriptor	S-adenosylmethionine synthase, PHOSPHATE ION, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	structural genomics, psi-biology, protein structure initiative, enzyme discovery for natural product biosynthesis, natpro, transferase
Biological source	Sulfolobus solfataricus
Total number of polymer chains	2
Total formula weight	91472.30
Authors	Wang, F.,Hurley, K.A.,Helmich, K.E.,Singh, S.,Bingman, C.A.,Thorson, J.S.,Phillips Jr., G.N.,Enzyme Discovery for Natural Product Biosynthesis (NatPro) (deposition date: 2013-06-13, release date: 2013-07-03, Last modification date: 2023-12-06)
Primary citation	Wang, F.,Singh, S.,Zhang, J.,Huber, T.D.,Helmich, K.E.,Sunkara, M.,Hurley, K.A.,Goff, R.D.,Bingman, C.A.,Morris, A.J.,Thorson, J.S.,Phillips, G.N. Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus. Febs J., 281:4224-4239, 2014 Cited by PubMed: 24649856 DOI: 10.1111/febs.12784 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.189 Å)

Structure validation