4NEO

Structure of BlmI, a type-II acyl-carrier-protein from Streptomyces verticillus involved in bleomycin biosynthesis

Replaces:  4I4D

Summary for 4NEO

• Entry DOI: 10.2210/pdb4neo/pdb
• Descriptor: Peptide synthetase NRPS type II-PCP, 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, ... (4 entities in total)
• Functional Keywords: structural genomics, psi-biology, enzyme discovery for natural product biosynthesis, natpro, peptide synthetase, biosynthetic protein, ligase, midwest center for structural genomics, mcsg
• Biological source: Streptomyces verticillus
• Total number of polymer chains: 1
• Total formula weight: 10549.53

Authors

Cuff, M.E.,Bigelow, L.,Bearden, J.,Babnigg, G.,Bruno, C.J.P.,Bingman, C.A.,Yennamalli, R.,Lohman, J.,Ma, M.,Shen, B.,Phillips Jr., G.N.,Joachimiak, A.,Enzyme Discovery for Natural Product Biosynthesis (NatPro),Midwest Center for Structural Genomics (MCSG) (deposition date: 2013-10-29, release date: 2014-01-29, Last modification date: 2023-03-22)

• Primary citation: Lohman, J.R.,Ma, M.,Cuff, M.E.,Bigelow, L.,Bearden, J.,Babnigg, G.,Joachimiak, A.,Phillips, G.N.,Shen, B.; The crystal structure of BlmI as a model for nonribosomal peptide synthetase peptidyl carrier proteins.; Proteins, 82:1210-1218, 2014; PubMed: 25050442; DOI: 10.1002/prot.24485

Experimental method

X-RAY DIFFRACTION (2.1 Å)