3L2C
 
 | | Crystal Structure of the DNA Binding Domain of FOXO4 Bound to DNA | | 分子名称: | FOXO consensus binding sequence, minus strand, plus strand, ... | | 著者 | Boura, E, Silhan, J, Sulc, M, Brynda, J, Obsilova, V, Obsil, T. | | 登録日 | 2009-12-15 | | 公開日 | 2009-12-29 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.868 Å) | | 主引用文献 | Structure of the human FOXO4-DBD-DNA complex at 1.9 A resolution reveals new details of FOXO binding to the DNA
Acta Crystallogr.,Sect.D, 66, 2010
|
|
3TOW
 | |
5NAS
 | |
8BXK
 | |
5LX2
 | |
6YWA
 | |
6YWB
 | |
7A90
 | | WT STING in complex with 3',3'-c-di[2'FdAM(PS)] | | 分子名称: | 9-[(1~{R},3~{R},6~{R},8~{R},9~{R},10~{R},12~{R},15~{R},17~{R},18~{R})-17-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanylidene)-3,12-bis(sulfanyl)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-8-yl]purin-6-amine, Stimulator of interferon protein | | 著者 | Boura, E, Smola, M. | | 登録日 | 2020-09-01 | | 公開日 | 2021-10-06 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.185 Å) | | 主引用文献 | WT STING in complex with 3',3'-c-di[2'FdAM(PS)]
To Be Published
|
|
4K7H
 | | Major capsid protein P1 of the Pseudomonas phage phi6 | | 分子名称: | Major inner protein P1 | | 著者 | Boura, E, Nemecek, D, Plevka, P, Steven, C.A, Hurley, J.H. | | 登録日 | 2013-04-17 | | 公開日 | 2013-08-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.5964 Å) | | 主引用文献 | Subunit Folds and Maturation Pathway of a dsRNA Virus Capsid.
Structure, 21, 2013
|
|
5I14
 | | Truncated and mutated T4 lysozyme | | 分子名称: | NICKEL (II) ION, mutated and truncated T4 lysozyme | | 著者 | Klima, M, Boura, E. | | 登録日 | 2016-02-05 | | 公開日 | 2016-02-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.745 Å) | | 主引用文献 | Metal ions-binding T4 lysozyme as an intramolecular protein purification tag compatible with X-ray crystallography.
Protein Sci., 26, 2017
|
|
2OJ4
 | | Crystal structure of RGS3 RGS domain | | 分子名称: | Regulator of G-protein signaling 3 | | 著者 | Boura, E, Obsil, T. | | 登録日 | 2007-01-12 | | 公開日 | 2007-01-30 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | 14-3-3 protein interacts with and affects the structure of RGS domain of regulator of G protein signaling 3 (RGS3).
J.Struct.Biol., 170, 2010
|
|
8CQH
 | |
6Y99
 | | hSTING mutant R232K in complex with 2',3'-cGAMP | | 分子名称: | Stimulator of interferon genes protein, cGAMP | | 著者 | Boura, E, Smola, M. | | 登録日 | 2020-03-06 | | 公開日 | 2021-03-31 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.984 Å) | | 主引用文献 | Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein.
Angew.Chem.Int.Ed.Engl., 60, 2021
|
|
6YDB
 | | Human wtSTING in complex with 2',2'-difluoro-3',3'-c-di-GMP | | 分子名称: | 2-azanyl-9-[(1~{R},6~{R},8~{R},9~{R},10~{R},15~{R},17~{R},18~{R})-17-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-8-yl]-1~{H}-purin-6-one, Stimulator of interferon protein | | 著者 | Boura, E, Smola, M. | | 登録日 | 2020-03-20 | | 公開日 | 2021-03-31 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | | 主引用文献 | Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein.
Angew.Chem.Int.Ed.Engl., 60, 2021
|
|
6YDZ
 | | Human wtSTING in complex with 3',3'-cGAMP | | 分子名称: | 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, Stimulator of interferon protein | | 著者 | Boura, E, Smola, M. | | 登録日 | 2020-03-23 | | 公開日 | 2021-03-31 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein.
Angew.Chem.Int.Ed.Engl., 60, 2021
|
|
6YEA
 | | Human wtSTING in complex with 2',2'-difluoro-3',3'-cGAMP | | 分子名称: | 2',2'-difluoro-3',3'-cGAMP, Stimulator of interferon protein | | 著者 | Boura, E, Smola, M. | | 登録日 | 2020-03-24 | | 公開日 | 2021-03-31 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.805 Å) | | 主引用文献 | Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein.
Angew.Chem.Int.Ed.Engl., 60, 2021
|
|
6Z15
 | | Human wtSTING in complex with 3',3'-c-di-AMP | | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Stimulator of interferon protein | | 著者 | Boura, E, Smola, M. | | 登録日 | 2020-05-12 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein.
Angew.Chem.Int.Ed.Engl., 60, 2021
|
|
6Z0Z
 | | Human wtSTING in complex with 3',3'-c-(2'FdAMP-2'FdAMP) | | 分子名称: | 2'-fluoro-,3',3'-c-di-AMP, Stimulator of interferon protein | | 著者 | Boura, E, Smola, M. | | 登録日 | 2020-05-11 | | 公開日 | 2021-05-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | | 主引用文献 | Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein.
Angew.Chem.Int.Ed.Engl., 60, 2021
|
|
6QSN
 | |
6S26
 | | Crystal structure of human wild type STING in complex with 2'-3'-cyclic-GMP-7-deaza-AMP | | 分子名称: | 2-azanyl-9-[(1~{R},6~{R},8~{R},9~{R},10~{S},15~{R},17~{R},18~{R})-8-(4-azanylpyrrolo[2,3-d]pyrimidin-7-yl)-3,9,12,18-tetrakis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecan-17-yl]-1~{H}-purin-6-one, Stimulator of interferon protein | | 著者 | Boura, E, Smola, M, Brynda, J. | | 登録日 | 2019-06-20 | | 公開日 | 2019-11-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Enzymatic Preparation of 2'-5',3'-5'-Cyclic Dinucleotides, Their Binding Properties to Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations.
J.Med.Chem., 62, 2019
|
|
8OIV
 | | Monkeypox virus VP39 in complex with SAH and cap0 | | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | | 著者 | Skvara, P, Chalupska, D, Silhan, J, Klima, M, Boura, E. | | 登録日 | 2023-03-23 | | 公開日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Structural basis for RNA-cap recognition and methylation by the mpox methyltransferase VP39.
Antiviral Res., 216, 2023
|
|
8OIX
 | | CryoEM structure of 20S Trichomonas vaginalis proteasome in complex with proteasome inhibitor Salinosporamid A | | 分子名称: | (3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE, Family T1, proteasome alpha subunit, ... | | 著者 | Silhan, J, Fajtova, P, Boura, E. | | 登録日 | 2023-03-23 | | 公開日 | 2024-04-10 | | 最終更新日 | 2024-04-17 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Tv20S proteasome in the complex with marizomib
To Be Published
|
|
4WAE
 | |
4WAG
 | |
8B07
 | |
