8OIV

Monkeypox virus VP39 in complex with SAH and cap0

Summary for 8OIV

Entry DOI	10.2210/pdb8oiv/pdb
Descriptor	Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, mGpppGAAAAA, S-ADENOSYL-L-HOMOCYSTEINE, ... (5 entities in total)
Functional Keywords	methyltransferase, ligand, monkeypox virus, transferase
Biological source	Monkeypox virus More
Total number of polymer chains	3
Total formula weight	75857.74
Authors	Skvara, P.,Chalupska, D.,Silhan, J.,Klima, M.,Boura, E. (deposition date: 2023-03-23, release date: 2023-08-23)
Primary citation	Skvara, P.,Chalupska, D.,Klima, M.,Kozic, J.,Silhan, J.,Boura, E. Structural basis for RNA-cap recognition and methylation by the mpox methyltransferase VP39. Antiviral Res., 216:105663-105663, 2023 Cited by PubMed: 37421984 DOI: 10.1016/j.antiviral.2023.105663 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.12 Å)

Structure validation