7A90

WT STING in complex with 3',3'-c-di[2'FdAM(PS)]

Summary for 7A90

• Entry DOI: 10.2210/pdb7a90/pdb
• Descriptor: Stimulator of interferon protein, 9-[(1~{R},3~{R},6~{R},8~{R},9~{R},10~{R},12~{R},15~{R},17~{R},18~{R})-17-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanylidene)-3,12-bis(sulfanyl)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-8-yl]purin-6-amine (2 entities in total)
• Functional Keywords: innate immune system, cyclic dinucleotides, protein binding
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 23885.60

Authors

Boura, E.,Smola, M. (deposition date: 2020-09-01, release date: 2021-10-06, Last modification date: 2024-01-31)

• Primary citation: Boura, E.,Smola, M.; WT STING in complex with 3',3'-c-di[2'FdAM(PS)]; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.185 Å)