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4FQQ
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Crystal Structure of Germline Antibody PGT121-GL Fab
分子名称: Fab heavy chain, Fab light chain, SODIUM ION
著者Scharf, L, Bjorkman, P.J.
登録日2012-06-25
公開日2012-11-14
最終更新日2021-05-19
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GW4
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BU of 4gw4 by Molmil
Crystal structure of 3BNC60 Fab with P61A mutation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC60 Fab Heavy-chain, 3BNC60 Fab Light-chain
著者Diskin, R, Fu, B.Z, Bjorkman, P.J.
登録日2012-08-31
公開日2013-04-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization.
Cell(Cambridge,Mass.), 153, 2013
4NHG
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BU of 4nhg by Molmil
Crystal Structure of 2G12 IgG Dimer
分子名称: 2G12 IgG dimer heavy chain, 2G12 IgG dimer light chain, Hepatitis B virus receptor binding protein
著者Wu, Y, West Jr, A.P, Kim, H.J, Thornton, M.E, Ward, A.B, Bjorkman, P.J.
登録日2013-11-05
公開日2014-02-26
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (8.001 Å)
主引用文献Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12.
Cell Rep, 5, 2013
4NHH
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Structure of 2G12 IgG Dimer
分子名称: 2G12 IgG dimer heavy chain, 2G12 IgG dimer light chain, Hepatitis B virus receptor binding protein
著者Wu, Y, West Jr, A.P, Kim, H.J, Thornton, M.E, Ward, A.B, Bjorkman, P.J.
登録日2013-11-05
公開日2014-02-26
実験手法X-RAY DIFFRACTION (6.5 Å)
主引用文献Structural basis for enhanced HIV-1 neutralization by a dimeric immunoglobulin G form of the glycan-recognizing antibody 2G12.
Cell Rep, 5, 2013
4P9M
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BU of 4p9m by Molmil
Crystal structure of 8ANC195 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 Fab heavy chain, 8ANC195 light chain
著者Scharf, L, Bjorkman, P.J.
登録日2014-04-04
公開日2014-05-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike.
Cell Rep, 7, 2014
4P9H
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BU of 4p9h by Molmil
Crystal structure of 8ANC195 Fab in complex with gp120 of 93TH057 HIV-1 and soluble CD4 D1D2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Scharf, L, Bjorkman, P.J.
登録日2014-04-04
公開日2014-05-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike.
Cell Rep, 7, 2014
4Q6Y
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Crystal structure of a chemoenzymatic glycoengineered disialylated Fc (di-sFc)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ahmed, A.A, Giddens, J, Pincetic, A, Lomino, J.V, Ravetch, J.V, Wang, L.X, Bjorkman, P.J.
登録日2014-04-23
公開日2014-07-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural characterization of anti-inflammatory immunoglobulin g fc proteins.
J.Mol.Biol., 426, 2014
4Q74
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F241A Fc
分子名称: Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Ahmed, A.A, Giddens, J, Pincetic, A, Lomino, J.V, Ravetch, J.V, Wang, L.X, Bjorkman, P.J.
登録日2014-04-24
公開日2014-07-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structural characterization of anti-inflammatory immunoglobulin g fc proteins.
J.Mol.Biol., 426, 2014
4Q7D
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BU of 4q7d by Molmil
Wild type Fc (wtFc)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region
著者Ahmed, A.A, Giddens, J, Pincetic, A, Lomino, J.V, Ravetch, J.V, Wang, L.X, Bjorkman, P.J.
登録日2014-04-24
公開日2014-07-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural characterization of anti-inflammatory immunoglobulin g fc proteins.
J.Mol.Biol., 426, 2014
5T3Z
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BU of 5t3z by Molmil
3.5 Angstrom Crystal Structure of a Fully and Natively Glycosylated BG505 SOSIP.664 HIV-1 Env Trimer in Complex with the Broadly Neutralizing Antibodies IOMA and 10-1074
分子名称: 10-1074 Heavy Chain, 10-1074 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gristick, H.B, Bjorkman, P.J.
登録日2016-08-26
公開日2016-10-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site.
Nat.Struct.Mol.Biol., 23, 2016
5THR
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BU of 5thr by Molmil
Cryo-EM structure of a BG505 Env-sCD4-17b-8ANC195 complex
分子名称: 17b Fab VH domain, 17b Fab VL domain, 8ANC195 G52K5 VH domain, ...
著者Wang, H, Bjorkman, P.J.
登録日2016-09-30
公開日2016-11-16
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (8.9 Å)
主引用文献Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T3X
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BU of 5t3x by Molmil
3.9 Angstrom Crystal Structure of a Fully and Natively Glycosylated BG505 SOSIP.664 HIV-1 Env Trimer in Complex with the Broadly Neutralizing Antibodies IOMA and 10-1074.
分子名称: 10-1074 Heavy Chain, 10-1074 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gristick, H.B, Bjorkman, P.J.
登録日2016-08-26
公開日2016-10-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site.
Nat.Struct.Mol.Biol., 23, 2016
5UEM
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BU of 5uem by Molmil
Crystal structure of 354NC37 Fab in complex with HIV-1 clade AE strain 93TH057 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 354NC37 Fab Heavy Chain, ...
著者Sievers, S.A, Gristick, H.B, Bjorkman, P.J.
登録日2017-01-02
公開日2018-01-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.
Sci Transl Med, 9, 2017
5UEL
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BU of 5uel by Molmil
Crystal structure of 354NC102 Fab
分子名称: 354NC102 Fab Heavy Chain, 354NC102 Fab Light Chain, SULFATE ION
著者Sievers, S.A, Gristick, H.B, Bjorkman, P.J.
登録日2017-01-02
公開日2017-02-01
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.
Sci Transl Med, 9, 2017
5UD9
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Crystal structure of 354BG18 Fab
分子名称: Fab heavy chain, Light chain
著者Scharf, L, Bjorkman, P.J.
登録日2016-12-23
公開日2017-02-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.
Sci Transl Med, 9, 2017
5VIY
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BG505 SOSIP.664 in complex with broadly neutralizing antibodies BG1 and 8ANC195
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 G52K5 Fab heavy chain, ...
著者Wang, H, Bjorkman, P.J.
登録日2017-04-17
公開日2017-06-21
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies.
Elife, 6, 2017
5VIC
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BU of 5vic by Molmil
Crystal structure of anti-Zika antibody Z004 bound to DENV-1 Envelope protein DIII
分子名称: Dengue 1 Envelope DIII domain, Fab heavy chain, Fab light chain
著者Keeffe, J.R, West Jr, A.P, Gristick, H.B, Bjorkman, P.J.
登録日2017-04-14
公開日2017-05-03
最終更新日2017-05-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico.
Cell, 169, 2017
5VIG
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BU of 5vig by Molmil
Crystal structure of anti-Zika antibody Z006 bound to Zika virus envelope protein DIII
分子名称: CITRATE ANION, Fab heavy chain, Fab light chain, ...
著者Keeffe, J.R, West Jr, A.P, Gristick, H.B, Bjorkman, P.J.
登録日2017-04-16
公開日2017-05-03
最終更新日2017-05-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico.
Cell, 169, 2017
5VJ6
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BG505 SOSIP.664 in complex with broadly neutralizing antibodies PG9 and 8ANC195
分子名称: 8ANC195 Fab heavy chain, 8ANC195 Fab light chain, Envelope glycoprotein gp160, ...
著者Wang, H, Bjorkman, P.J.
登録日2017-04-18
公開日2017-06-21
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (11.5 Å)
主引用文献Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies.
Elife, 6, 2017
5VVF
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Crystal Structure of 354BG1 Fab
分子名称: 1,2-ETHANEDIOL, 354BG1 Heavy Chain, 354BG1 Light Chain
著者Scharf, L, Gristick, H.B, Bjorkman, P.J.
登録日2017-05-19
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies.
Elife, 6, 2017
1EXU
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BU of 1exu by Molmil
CRYSTAL STRUCTURE OF THE HUMAN MHC-RELATED FC RECEPTOR
分子名称: BETA-2-MICROGLOBULIN, BETA-MERCAPTOETHANOL, IGG RECEPTOR FCRN LARGE SUBUNIT P51
著者West Jr, A.P, Bjorkman, P.J.
登録日2000-05-04
公開日2000-08-10
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure and immunoglobulin G binding properties of the human major histocompatibility complex-related Fc receptor(,).
Biochemistry, 39, 2000
1FJR
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BU of 1fjr by Molmil
CRYSTAL STRUCTURE OF THE ECTODOMAIN OF METHUSELAH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LEAD (II) ION, ...
著者West Jr, A.P, Llamas, L.L, Snow, P.M, Benzer, S, Bjorkman, P.J.
登録日2000-08-08
公開日2001-04-04
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the ectodomain of Methuselah, a Drosophila G protein-coupled receptor associated with extended lifespan.
Proc.Natl.Acad.Sci.USA, 98, 2001
1FWV
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CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF MANNOSE RECEPTOR COMPLEXED WITH 3-SO4-LEWIS(A)
分子名称: 3-O-sulfo-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, CYSTEINE-RICH DOMAIN OF MANNOSE RECEPTOR
著者Liu, Y, Misulovin, Z, Bjorkman, P.J.
登録日2000-09-24
公開日2001-01-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The molecular mechanism of sulfated carbohydrate recognition by the cysteine-rich domain of mannose receptor.
J.Mol.Biol., 305, 2001
1FWU
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CRYSTAL STRUCTURE OF THE CYSTEINE-RICH DOMAIN OF MANNOSE RECEPTOR COMPLEXED WITH 3-SO4-LEWIS(X)
分子名称: CYSTEINE-RICH DOMAIN OF MANNOSE RECEPTOR, alpha-L-fucopyranose-(1-3)-[3-O-sulfo-beta-D-galactopyranose-(1-4)]methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside
著者Liu, Y, Misulovin, Z, Bjorkman, P.J.
登録日2000-09-24
公開日2001-01-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The molecular mechanism of sulfated carbohydrate recognition by the cysteine-rich domain of mannose receptor.
J.Mol.Biol., 305, 2001
1G0X
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CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF LIR-1 (ILT2)
分子名称: LEUCOCYTE IMMUNOGLOBULIN-LIKE RECEPTOR-1
著者Chapman, T.L, Heikema, A.P, West Jr, A.P, Bjorkman, P.J.
登録日2000-10-09
公開日2001-01-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure and ligand binding properties of the D1D2 region of the inhibitory receptor LIR-1 (ILT2).
Immunity, 13, 2000

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