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3Q7F
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BU of 3q7f by Molmil
Cryptococcus neoformans protein farnesyltransferase in complex with FPP and ethylenediamine inhibitor 1
Descriptor: (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, FARNESYL DIPHOSPHATE, Farnesyltransferase alpha subunit, ...
Authors:Hast, M.A, Beese, L.S.
Deposit date:2011-01-04
Release date:2011-08-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens.
J.Biol.Chem., 286, 2011
1TN7
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BU of 1tn7 by Molmil
Protein Farnesyltransferase Complexed with a TC21 Peptide Substrate and a FPP Analog at 2.3A Resolution
Descriptor: ACETIC ACID, Fusion protein, Protein farnesyltransferase alpha subunit, ...
Authors:Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S.
Deposit date:2004-06-11
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.
J.Mol.Biol., 343, 2004
1TNU
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BU of 1tnu by Molmil
Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a GCINCCKVL Peptide Derived from RhoB
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE, CHLORIDE ION, ...
Authors:Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S.
Deposit date:2004-06-11
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.
J.Mol.Biol., 343, 2004
1TN6
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BU of 1tn6 by Molmil
Protein Farnesyltransferase Complexed with a Rap2a Peptide Substrate and a FPP Analog at 1.8A Resolution
Descriptor: ACETIC ACID, Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ...
Authors:Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S.
Deposit date:2004-06-11
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity
J.Mol.Biol., 343, 2004
1TNB
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BU of 1tnb by Molmil
Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a substrate KKSKTKCVIF Peptide Derived from TC21
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE, CHLORIDE ION, ...
Authors:Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S.
Deposit date:2004-06-11
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.
J.Mol.Biol., 343, 2004
1TNO
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BU of 1tno by Molmil
Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a KKKSKTKCVIM Peptide Derived from K-Ras4B
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE, CHLORIDE ION, ...
Authors:Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S.
Deposit date:2004-06-11
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.
J.Mol.Biol., 343, 2004
1TN8
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BU of 1tn8 by Molmil
Protein Farnesyltransferase Complexed with a H-Ras Peptide Substrate and a FPP Analog at 2.25A Resolution
Descriptor: ACETIC ACID, Protein farnesyltransferase beta subunit, Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit, ...
Authors:Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S.
Deposit date:2004-06-11
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.
J.Mol.Biol., 343, 2004
1TNY
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BU of 1tny by Molmil
Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a FREKKFFCAIL Peptide Derived from the Heterotrimeric G Protein Gamma-2 Subunit
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE, CHLORIDE ION, ...
Authors:S Reid, T, Terry, K.L, Casey, P.J, Beese, L.S.
Deposit date:2004-06-11
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.
J.Mol.Biol., 343, 2004
1TNZ
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BU of 1tnz by Molmil
Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a RRCVLL Peptide Derived from Cdc42 splice isoform-2
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE, CHLORIDE ION, ...
Authors:Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S.
Deposit date:2004-06-11
Release date:2004-11-02
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.
J.Mol.Biol., 343, 2004
1QHT
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BU of 1qht by Molmil
DNA POLYMERASE FROM THERMOCOCCUS SP. 9ON-7 ARCHAEON
Descriptor: PROTEIN (DNA POLYMERASE)
Authors:Park, H.-W, Rodriguez, A.C, Beese, L.S.
Deposit date:1999-05-26
Release date:2000-05-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of a pol alpha family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. 9 degrees N-7.
J.Mol.Biol., 299, 2000
3SFX
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BU of 3sfx by Molmil
Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and tipifarnib
Descriptor: (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, 6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-4-(3-CHLOROPHENYL)-1-METHYLQUINOLIN-2(1H)-ONE, Cryptococcus neoformans protein farnesyltransferase alpha subunit, ...
Authors:Hast, M.A, Beese, L.S.
Deposit date:2011-06-14
Release date:2011-08-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens.
J.Biol.Chem., 286, 2011
3SFY
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BU of 3sfy by Molmil
Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and ethylenediamine inhibitor 2
Descriptor: (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, Cryptococcus neoformans protein farnesyltransferase alpha subunit, Cryptococcus neoformans protein farnesyltransferase beta subunit, ...
Authors:Hast, M.A, Beese, L.S.
Deposit date:2011-06-14
Release date:2011-08-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens.
J.Biol.Chem., 286, 2011
3SRY
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BU of 3sry by Molmil
Engineered high-affinity halide-binding protein derived from YFP: halide-free
Descriptor: Green fluorescent protein
Authors:Wang, W, Grimley, J.S, Beese, L.S, Hellinga, H.W.
Deposit date:2011-07-07
Release date:2012-07-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.159 Å)
Cite:Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be Published
3SVB
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BU of 3svb by Molmil
Engineered medium-affinity halide-binding protein derived from YFP: fluoride complex
Descriptor: 1,2-ETHANEDIOL, Green fluorescent protein
Authors:Wang, W, Grimley, J.S, Beese, L.S, Hellinga, H.W.
Deposit date:2011-07-12
Release date:2012-07-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be Published
3SST
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BU of 3sst by Molmil
Engineered low-affinity halide-binding protein derived from YFP: chloride complex
Descriptor: CHLORIDE ION, Green fluorescent protein
Authors:Wang, W, Grimley, J.S, Beese, L.S, Hellinga, H.W.
Deposit date:2011-07-08
Release date:2012-07-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.403 Å)
Cite:Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be Published
3SVE
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BU of 3sve by Molmil
Engineered low-affinity halide-binding protein derived from YFP: bromide complex
Descriptor: BROMIDE ION, Green fluorescent protein
Authors:Wang, W, Grimley, J.S, Beese, L.S, Hellinga, H.W.
Deposit date:2011-07-12
Release date:2012-07-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.492 Å)
Cite:Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be Published
3SV5
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BU of 3sv5 by Molmil
Engineered medium-affinity halide-binding protein derived from YFP: iodide complex
Descriptor: 1,2-ETHANEDIOL, FORMIC ACID, Green fluorescent protein, ...
Authors:Wang, W, Grimley, J.S, Beese, L.S, Hellinga, H.W.
Deposit date:2011-07-12
Release date:2012-07-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Visualization of Synaptic Inhibition with an Optogenetic Sensor Developed by Cell-Free Protein Engineering Automation.
J.Neurosci., 33, 2013
3SSK
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BU of 3ssk by Molmil
Engineered high-affinity halide-binding protein derived from YFP: bromide complex
Descriptor: BROMIDE ION, Green fluorescent protein
Authors:Wang, W, Grimley, J.S, Beese, L.S, Hellinga, H.W.
Deposit date:2011-07-08
Release date:2012-07-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.361 Å)
Cite:Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be Published
3SS0
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BU of 3ss0 by Molmil
Engineered high-affinity halide-binding protein derived from YFP: fluoride complex
Descriptor: Green fluorescent protein
Authors:Wang, W, Grimley, J.S, Beese, L.S, Hellinga, H.W.
Deposit date:2011-07-07
Release date:2012-07-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.492 Å)
Cite:Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be Published
3SSH
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BU of 3ssh by Molmil
Engineered high-affinity halide-binding protein derived from YFP: chloride complex
Descriptor: CHLORIDE ION, Green fluorescent protein
Authors:Wang, W, Grimley, J.S, Beese, L.S, Hellinga, H.W.
Deposit date:2011-07-08
Release date:2012-07-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.277 Å)
Cite:Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be Published
3SVC
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BU of 3svc by Molmil
Engineered medium-affinity halide-binding protein derived from YFP: chloride complex
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Green fluorescent protein
Authors:Wang, W, Grimley, J.S, Beese, L.S, Hellinga, H.W.
Deposit date:2011-07-12
Release date:2012-07-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be Published
3SSL
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BU of 3ssl by Molmil
Engineered high-affinity halide-binding protein derived from YFP: iodide complex
Descriptor: Green fluorescent protein, IODIDE ION
Authors:Wang, W, Grimley, J.S, Beese, L.S, Hellinga, H.W.
Deposit date:2011-07-08
Release date:2012-07-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be published
3SSY
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BU of 3ssy by Molmil
Engineered low-affinity halide-binding protein derived from YFP: iodide complex
Descriptor: Green fluorescent protein, IODIDE ION
Authors:Wang, W, Grimley, J.S, Beese, L.S, Hellinga, H.W.
Deposit date:2011-07-08
Release date:2012-07-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.769 Å)
Cite:Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be Published
3ST0
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BU of 3st0 by Molmil
Engineered medium-affinity halide-binding protein derived from YFP: halide-free
Descriptor: 1,2-ETHANEDIOL, FORMIC ACID, Green fluorescent protein
Authors:Wang, W, Grimley, J.S, Beese, L.S, Hellinga, H.W.
Deposit date:2011-07-08
Release date:2012-07-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:Visualization of Synaptic Inhibition with an Optogenetic Sensor Developed by Cell-Free Protein Engineering Automation.
J.Neurosci., 33, 2013
3SSP
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BU of 3ssp by Molmil
Engineered low-affinity halide-binding protein derived from YFP: halide-free
Descriptor: Green fluorescent protein
Authors:Wang, W, Grimley, J.S, Beese, L.S, Hellinga, H.W.
Deposit date:2011-07-08
Release date:2012-07-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.628 Å)
Cite:Determination of engineered chloride-binding site structures in fluorescent proteins reveals principles of halide recognition
To be Published

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