1DNC
 
 | | HUMAN GLUTATHIONE REDUCTASE MODIFIED BY DIGLUTATHIONE-DINITROSO-IRON | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE, GLUTATHIONE REDUCTASE, ... | | 著者 | Becker, K, Savvides, S.N, Keese, M, Schirmer, R.H, Karplus, P.A. | | 登録日 | 1998-02-20 | | 公開日 | 1998-05-27 | | 最終更新日 | 2011-12-07 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Enzyme inactivation through sulfhydryl oxidation by physiologic NO-carriers.
Nat.Struct.Biol., 5, 1998
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1GSN
 | | HUMAN GLUTATHIONE REDUCTASE MODIFIED BY DINITROSOGLUTATHIONE | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE, GLUTATHIONE REDUCTASE, ... | | 著者 | Becker, K, Savvides, S.N, Keese, M, Schirmer, R.H, Karplus, P.A. | | 登録日 | 1998-02-21 | | 公開日 | 1998-05-27 | | 最終更新日 | 2011-12-07 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Enzyme inactivation through sulfhydryl oxidation by physiologic NO-carriers.
Nat.Struct.Biol., 5, 1998
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1ALG
 | | SOLUTION STRUCTURE OF AN HGR INHIBITOR, NMR, 10 STRUCTURES | | 分子名称: | P11 | | 著者 | Schott, M.K, Nordhoff, A, Becker, K, Kalbitzer, H.R, Schirmer, R.H. | | 登録日 | 1997-06-03 | | 公開日 | 1997-10-15 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Denaturation and reactivation of dimeric human glutathione reductase--an assay for folding inhibitors.
Eur.J.Biochem., 245, 1997
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8C79
 | | Crystal structure of Leishmania donovani 6-Phosphogluconate Dehydrogenase complexed with NADPH | | 分子名称: | 6-phosphogluconate dehydrogenase, decarboxylating, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Fritz-Wolf, K, Berneburg, I, Rahlfs, S, Becker, K. | | 登録日 | 2023-01-13 | | 公開日 | 2023-05-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure of Leishmania donovani 6-Phosphogluconate Dehydrogenase and Inhibition by Phosphine Gold(I) Complexes: A Potential Approach to Leishmaniasis Treatment.
Int J Mol Sci, 24, 2023
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7PCZ
 | | Functional and structural characterization of redox sensitive superfolder green fluorescent protein and variants | | 分子名称: | ETHANOL, GLYCEROL, Green fluorescent protein | | 著者 | Fritz-Wolf, K, Heimsch, K.C, Schuh, A.K, Becker, K. | | 登録日 | 2021-08-04 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structure and Function of Redox-Sensitive Superfolder Green Fluorescent Protein Variant.
Antioxid.Redox Signal., 37, 2022
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7PD0
 | | Functional and structural characterization of redox sensitive superfolder green fluorescent protein and variants | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Green fluorescent protein, ... | | 著者 | Fritz-Wolf, K, Heimsch, K.C, Schuh, A.K, Becker, K. | | 登録日 | 2021-08-04 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure and Function of Redox-Sensitive Superfolder Green Fluorescent Protein Variant.
Antioxid.Redox Signal., 37, 2022
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7PCA
 | | Functional and structural characterization of redox sensitive superfolder green fluorescent protein and variants | | 分子名称: | ETHANOL, FORMAMIDE, GLYCEROL, ... | | 著者 | Fritz-Wolf, K, Heimsch, K.C, Schuh, A.K, Becker, K. | | 登録日 | 2021-08-03 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Structure and Function of Redox-Sensitive Superfolder Green Fluorescent Protein Variant.
Antioxid.Redox Signal., 37, 2022
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5LM3
 | | Plasmodium falciparum nicotinic acid mononucleotide adenylyltransferase complexed with APC | | 分子名称: | 1,2-ETHANEDIOL, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, Nicotinate-nucleotide adenylyltransferase | | 著者 | Bathke, J, Fritz-Wolf, K, Rahlfs, S, Brandstaether, C, Burkhardt, A, Becker, K. | | 登録日 | 2016-07-29 | | 公開日 | 2016-11-30 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural and Functional Characterization of Plasmodium falciparum Nicotinic Acid Mononucleotide Adenylyltransferase.
J. Mol. Biol., 428, 2016
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5LLT
 | | Plasmodium falciparum nicotinic acid mononucleotide adenylyltransferase complexed with NaAD | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NICOTINIC ACID ADENINE DINUCLEOTIDE, ... | | 著者 | Bathke, J, Fritz-Wolf, K, Brandstaedter, C, Rahlfs, S, Becker, K. | | 登録日 | 2016-07-28 | | 公開日 | 2016-11-30 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural and Functional Characterization of Plasmodium falciparum Nicotinic Acid Mononucleotide Adenylyltransferase.
J. Mol. Biol., 428, 2016
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1OKT
 | | X-ray Structure of Glutathione S-Transferase from the Malarial Parasite Plasmodium falciparum | | 分子名称: | FORMIC ACID, GLUTATHIONE S-TRANSFERASE | | 著者 | Fritz-Wolf, K, Becker, A, Rahlfs, s, Harwaldt, P, Schirmer, R.H, Kabsch, W, Becker, K. | | 登録日 | 2003-07-29 | | 公開日 | 2003-11-20 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | X-Ray Structure of Glutathione S-Transferase from the Malarial Parasite Plasmodium Falciparum
Proc.Natl.Acad.Sci.USA, 100, 2003
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7AOJ
 | | Plasmoredoxin, a redox-active protein unique for malaria parasites | | 分子名称: | GLYCEROL, Plasmoredoxin | | 著者 | Fritz-Wolf, K, Bathke, J, Rahlfs, S, Becker, K. | | 登録日 | 2020-10-14 | | 公開日 | 2022-04-13 | | 最終更新日 | 2022-04-27 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Crystal structure of plasmoredoxin, a redox-active protein unique for malaria parasites.
Curr Res Struct Biol, 4, 2022
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7AOO
 | | Plasmoredoxin, a redox-active protein unique for malaria parasites | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, HEXAETHYLENE GLYCOL, ... | | 著者 | Fritz-Wolf, K, Bathke, J, Rahlfs, S, Becker, K. | | 登録日 | 2020-10-14 | | 公開日 | 2022-04-13 | | 最終更新日 | 2022-04-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of plasmoredoxin, a redox-active protein unique for malaria parasites.
Curr Res Struct Biol, 4, 2022
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3LG0
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7ZZI
 | | Plasmodium falciparum hexokinase complexed with glucose and citrate | | 分子名称: | 1,2-ETHANEDIOL, CITRIC ACID, Phosphotransferase, ... | | 著者 | Fritz-Wolf, K, Dillenberger, M, Rahlfs, S, Becker, K. | | 登録日 | 2022-05-25 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Analysis of Plasmodium falciparum Hexokinase Provides Novel Information about Catalysis Due to a Plasmodium -Specific Insertion.
Int J Mol Sci, 24, 2023
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6FQY
 | | Plasmodium falciparum 6-phosphogluconate dehydrogenase in its apo form, in complex with its cofactor NADP+ and in complex with its substrate 6-phosphogluconate | | 分子名称: | 1,2-ETHANEDIOL, 6-phosphogluconate dehydrogenase, decarboxylating, ... | | 著者 | Fritz-Wolf, K, Haeussler, K, Reichmann, M, Rahlfs, S, Becker, K. | | 登録日 | 2018-02-15 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Characterization of Plasmodium falciparum 6-Phosphogluconate Dehydrogenase as an Antimalarial Drug Target.
J. Mol. Biol., 430, 2018
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6FQX
 | | Plasmodium falciparum 6-phosphogluconate dehydrogenase in its apo form, in complex with its cofactor NADP+ and in complex with its substrate 6-phosphogluconate | | 分子名称: | 2-(2-ETHOXYETHOXY)ETHANOL, 6-phosphogluconate dehydrogenase, decarboxylating, ... | | 著者 | Fritz-Wolf, K, Haeussler, K, Reichmann, M, Rahlfs, S, Becker, K. | | 登録日 | 2018-02-15 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Characterization of Plasmodium falciparum 6-Phosphogluconate Dehydrogenase as an Antimalarial Drug Target.
J. Mol. Biol., 430, 2018
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6FQZ
 | | Plasmodium falciparum 6-phosphogluconate dehydrogenase in its apo form, in complex with its cofactor NADP+ and in complex with its substrate 6-phosphogluconate | | 分子名称: | 6-PHOSPHOGLUCONIC ACID, 6-phosphogluconate dehydrogenase, decarboxylating, ... | | 著者 | Fritz-Wolf, K, Haeussler, K, Reichmann, M, Rahlfs, S, Becker, K. | | 登録日 | 2018-02-15 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Characterization of Plasmodium falciparum 6-Phosphogluconate Dehydrogenase as an Antimalarial Drug Target.
J. Mol. Biol., 430, 2018
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4J57
 | | Structure of Plasmodium falciparum thioredoxin reductase-thioredoxin complex | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Thioredoxin, ... | | 著者 | Fritz-Wolf, K, Jortzik, E, Stumpf, M, Preuss, J, Iozef, R, Rahlfs, S, Becker, K. | | 登録日 | 2013-02-08 | | 公開日 | 2013-07-10 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of the Plasmodium falciparum Thioredoxin Reductase-Thioredoxin Complex.
J.Mol.Biol., 425, 2013
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4J56
 | | Structure of Plasmodium falciparum thioredoxin reductase-thioredoxin complex | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin, Thioredoxin reductase 2 | | 著者 | Fritz-Wolf, K, Jortzik, E, Stumpf, M, Preuss, J, Iozef, R, Rahlfs, S, Becker, K. | | 登録日 | 2013-02-08 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.371 Å) | | 主引用文献 | Crystal Structure of the Plasmodium falciparum Thioredoxin Reductase-Thioredoxin Complex.
J.Mol.Biol., 425, 2013
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2AAQ
 | | Crystal Structure Analysis of the human Glutahione Reductase, complexed with GoPI | | 分子名称: | 2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Urig, S, Fritz-Wolf, K, Reau, R, Herold-Mende, C, Toth, K, Davioud-Charvet, E, Becker, K. | | 登録日 | 2005-07-14 | | 公開日 | 2006-04-04 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Undressing of Phosphine Gold(I) Complexes as Irreversible Inhibitors of Human Disulfide Reductases.
Angew.Chem.Int.Ed.Engl., 45, 2006
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3R3J
 | | Kinetic and structural characterization of Plasmodium falciparum glutamate dehydrogenase 2 | | 分子名称: | Glutamate dehydrogenase | | 著者 | Zocher, K, Fritz-Wolf, K, Kehr, S, Rahlfs, S, Becker, K. | | 登録日 | 2011-03-16 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Biochemical and structural characterization of Plasmodium falciparum glutamate dehydrogenase 2.
Mol.Biochem.Parasitol., 183, 2012
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7Z4M
 | | Plasmodium falciparum pyruvate kinase complexed with Mg2+ and K+ | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Dillenberger, M, Rahlfs, S, Becker, K, Fritz-Wolf, K. | | 登録日 | 2022-03-04 | | 公開日 | 2022-08-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Prominent role of cysteine residues C49 and C343 in regulating Plasmodium falciparum pyruvate kinase activity.
Structure, 30, 2022
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7Z4Q
 | | Plasmodium falciparum pyruvate kinase mutant - C49A | | 分子名称: | MAGNESIUM ION, Pyruvate kinase | | 著者 | Dillenberger, M, Rahlfs, S, Becker, K, Fritz-Wolf, K. | | 登録日 | 2022-03-04 | | 公開日 | 2022-08-24 | | 最終更新日 | 2022-10-19 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Prominent role of cysteine residues C49 and C343 in regulating Plasmodium falciparum pyruvate kinase activity.
Structure, 30, 2022
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7Z4N
 | | Plasmodium falciparum pyruvate kinase complexed with pyruvate | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Dillenberger, M, Rahlfs, S, Becker, K, Fritz-Wolf, K. | | 登録日 | 2022-03-04 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Prominent role of cysteine residues C49 and C343 in regulating Plasmodium falciparum pyruvate kinase activity.
Structure, 30, 2022
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7Z4R
 | | Plasmodium falciparum pyruvate kinase mutant - C343A | | 分子名称: | MAGNESIUM ION, POTASSIUM ION, Pyruvate kinase | | 著者 | Dillenberger, M, Rahlfs, S, Becker, K, Fritz-Wolf, K. | | 登録日 | 2022-03-04 | | 公開日 | 2022-08-24 | | 最終更新日 | 2022-10-19 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Prominent role of cysteine residues C49 and C343 in regulating Plasmodium falciparum pyruvate kinase activity.
Structure, 30, 2022
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