7Z4N

Plasmodium falciparum pyruvate kinase complexed with pyruvate

Summary for 7Z4N

Entry DOI	10.2210/pdb7z4n/pdb
Related	7Z4M 7Z4Q 7Z4R
Descriptor	Pyruvate kinase, MAGNESIUM ION, POTASSIUM ION, ... (8 entities in total)
Functional Keywords	redox regulation, glycolysis, malaria, drug-target, transferase
Biological source	Plasmodium falciparum 3D7
Total number of polymer chains	1
Total formula weight	58444.02
Authors	Dillenberger, M.,Rahlfs, S.,Becker, K.,Fritz-Wolf, K. (deposition date: 2022-03-04, release date: 2022-08-24, Last modification date: 2023-11-15)
Primary citation	Dillenberger, M.,Rahlfs, S.,Becker, K.,Fritz-Wolf, K. Prominent role of cysteine residues C49 and C343 in regulating Plasmodium falciparum pyruvate kinase activity. Structure, 30:1452-, 2022 Cited by PubMed: 35998635 DOI: 10.1016/j.str.2022.08.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation