1GSN
HUMAN GLUTATHIONE REDUCTASE MODIFIED BY DINITROSOGLUTATHIONE
Summary for 1GSN
Entry DOI | 10.2210/pdb1gsn/pdb |
Descriptor | GLUTATHIONE REDUCTASE, PHOSPHATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total) |
Functional Keywords | sulfhydryl oxidation, sulfenic acid, nitric oxide, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Isoform Mitochondrial: Mitochondrion. Isoform Cytoplasmic: Cytoplasm: P00390 |
Total number of polymer chains | 1 |
Total formula weight | 52888.09 |
Authors | Becker, K.,Savvides, S.N.,Keese, M.,Schirmer, R.H.,Karplus, P.A. (deposition date: 1998-02-21, release date: 1998-05-27, Last modification date: 2011-12-07) |
Primary citation | Becker, K.,Savvides, S.N.,Keese, M.,Schirmer, R.H.,Karplus, P.A. Enzyme inactivation through sulfhydryl oxidation by physiologic NO-carriers. Nat.Struct.Biol., 5:267-271, 1998 Cited by PubMed: 9546215DOI: 10.1038/nsb0498-267 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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