7Z4M

Plasmodium falciparum pyruvate kinase complexed with Mg2+ and K+

Summary for 7Z4M

• Entry DOI: 10.2210/pdb7z4m/pdb
• Related: 7Z4N 7Z4Q 7Z4R
• Descriptor: Pyruvate kinase, MAGNESIUM ION, POTASSIUM ION, ... (6 entities in total)
• Functional Keywords: redox regulation, glycolysis, malaria, drug-target, transferase
• Biological source: Plasmodium falciparum 3D7
• Total number of polymer chains: 1
• Total formula weight: 57261.74

Authors

Dillenberger, M.,Rahlfs, S.,Becker, K.,Fritz-Wolf, K. (deposition date: 2022-03-04, release date: 2022-08-24, Last modification date: 2024-01-31)

• Primary citation: Dillenberger, M.,Rahlfs, S.,Becker, K.,Fritz-Wolf, K.; Prominent role of cysteine residues C49 and C343 in regulating Plasmodium falciparum pyruvate kinase activity.; Structure, 30:1452-, 2022; PubMed: 35998635; DOI: 10.1016/j.str.2022.08.001

Experimental method

X-RAY DIFFRACTION (1.9 Å)