7Z4M
Plasmodium falciparum pyruvate kinase complexed with Mg2+ and K+
Summary for 7Z4M
Entry DOI | 10.2210/pdb7z4m/pdb |
Related | 7Z4N 7Z4Q 7Z4R |
Descriptor | Pyruvate kinase, MAGNESIUM ION, POTASSIUM ION, ... (6 entities in total) |
Functional Keywords | redox regulation, glycolysis, malaria, drug-target, transferase |
Biological source | Plasmodium falciparum 3D7 |
Total number of polymer chains | 1 |
Total formula weight | 57261.74 |
Authors | Dillenberger, M.,Rahlfs, S.,Becker, K.,Fritz-Wolf, K. (deposition date: 2022-03-04, release date: 2022-08-24, Last modification date: 2024-01-31) |
Primary citation | Dillenberger, M.,Rahlfs, S.,Becker, K.,Fritz-Wolf, K. Prominent role of cysteine residues C49 and C343 in regulating Plasmodium falciparum pyruvate kinase activity. Structure, 30:1452-, 2022 Cited by PubMed: 35998635DOI: 10.1016/j.str.2022.08.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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