1S54
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![BU of 1s54 by Molmil](/molmil-images/mine/1s54) | Thr24Ala Bacteriorhodopsin | Descriptor: | RETINAL, bacteriorhodopsin | Authors: | Yohannan, S, Faham, S, Yang, D, Grosfeld, D, Chamberlain, A.K, Bowie, J.U. | Deposit date: | 2004-01-19 | Release date: | 2004-03-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A C(alpha)-H.O Hydrogen Bond in a Membrane Protein Is Not Stabilizing J.Am.Chem.Soc., 126, 2004
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8JTS
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![BU of 8jts by Molmil](/molmil-images/mine/8jts) | hOCT1 in complex with metformin in outward open conformation | Descriptor: | Metformin, Solute carrier family 22 member 1 | Authors: | Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. | Deposit date: | 2023-06-22 | Release date: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.14 Å) | Cite: | Structural insights into human organic cation transporter 1 transport and inhibition. Cell Discov, 10, 2024
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8JU0
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![BU of 8ju0 by Molmil](/molmil-images/mine/8ju0) | hOCT1 in complex with spironolactone in inward facing occluded conformation | Descriptor: | SPIRONOLACTONE, Solute carrier family 22 member 1 | Authors: | Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. | Deposit date: | 2023-06-23 | Release date: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Structural insights into human organic cation transporter 1 transport and inhibition. Cell Discov, 10, 2024
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8JTW
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![BU of 8jtw by Molmil](/molmil-images/mine/8jtw) | hOCT1 in complex with nb5660 in inward facing partially open 1 conformation | Descriptor: | Solute carrier family 22 member 1, nanobody 56 | Authors: | Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. | Deposit date: | 2023-06-22 | Release date: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Structural insights into human organic cation transporter 1 transport and inhibition. Cell Discov, 10, 2024
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8JTX
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![BU of 8jtx by Molmil](/molmil-images/mine/8jtx) | hOCT1 in complex with nb5660 in inward facing fully open conformation | Descriptor: | Solute carrier family 22 member 1, nanobody 56 | Authors: | Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. | Deposit date: | 2023-06-22 | Release date: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Structural insights into human organic cation transporter 1 transport and inhibition. Cell Discov, 10, 2024
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8JTZ
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![BU of 8jtz by Molmil](/molmil-images/mine/8jtz) | hOCT1 in complex with spironolactone in outward facing partially occluded conformation | Descriptor: | SPIRONOLACTONE, Solute carrier family 22 member 1 | Authors: | Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. | Deposit date: | 2023-06-22 | Release date: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Structural insights into human organic cation transporter 1 transport and inhibition. Cell Discov, 10, 2024
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8JTT
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![BU of 8jtt by Molmil](/molmil-images/mine/8jtt) | hOCT1 in complex with metformin in outward occluded conformation | Descriptor: | Metformin, Solute carrier family 22 member 1 | Authors: | Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. | Deposit date: | 2023-06-22 | Release date: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.87 Å) | Cite: | Structural insights into human organic cation transporter 1 transport and inhibition. Cell Discov, 10, 2024
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8JTY
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![BU of 8jty by Molmil](/molmil-images/mine/8jty) | hOCT1 in complex with nb5660 in inward facing partially open 2 conformation | Descriptor: | Solute carrier family 22 member 1, nanobody 56 | Authors: | Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. | Deposit date: | 2023-06-22 | Release date: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Structural insights into human organic cation transporter 1 transport and inhibition. Cell Discov, 10, 2024
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8JTV
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![BU of 8jtv by Molmil](/molmil-images/mine/8jtv) | hOCT1 in complex with metformin in inward occluded conformation | Descriptor: | Metformin, Solute carrier family 22 member 1 | Authors: | Zhang, S, Zhu, A, Kong, F, Chen, J, Lan, B, He, G, Gao, K, Cheng, L, Yan, C, Chen, L, Liu, X. | Deposit date: | 2023-06-22 | Release date: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.77 Å) | Cite: | Structural insights into human organic cation transporter 1 transport and inhibition. Cell Discov, 10, 2024
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5BO5
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![BU of 5bo5 by Molmil](/molmil-images/mine/5bo5) | Structure of a unique ATP synthase subunit NeqB from Nanoarcheaum equitans | Descriptor: | MAGNESIUM ION, NEQ263, SULFATE ION | Authors: | Mohanty, S, Jobichen, C, Chichili, V.P.R, Sivaraman, J. | Deposit date: | 2015-05-27 | Release date: | 2015-09-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.808 Å) | Cite: | Structural Basis for a Unique ATP Synthase Core Complex from Nanoarcheaum equitans J.Biol.Chem., 290, 2015
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5GVX
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![BU of 5gvx by Molmil](/molmil-images/mine/5gvx) | Structural insight into dephosphorylation by Trehalose 6-phosphate Phosphatase (OtsB2) from Mycobacterium Tuberculosis | Descriptor: | MAGNESIUM ION, Trehalose-phosphate phosphatase | Authors: | Shan, S, Min, H, Liu, T, Jiang, D, Rao, Z. | Deposit date: | 2016-09-07 | Release date: | 2017-09-27 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.596 Å) | Cite: | Structural insight into dephosphorylation by trehalose 6-phosphate phosphatase (OtsB2) from Mycobacterium tuberculosis. FASEB J., 30, 2016
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1TN5
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![BU of 1tn5 by Molmil](/molmil-images/mine/1tn5) | Structure of bacterorhodopsin mutant K41P | Descriptor: | Bacteriorhodopsin, RETINAL | Authors: | Yohannan, S, Yang, D, Faham, S, Boulting, G, Whitelegge, J, Bowie, J.U. | Deposit date: | 2004-06-11 | Release date: | 2004-10-19 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Proline substitutions are not easily accommodated in a membrane protein J.Mol.Biol., 341, 2004
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1TN0
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![BU of 1tn0 by Molmil](/molmil-images/mine/1tn0) | Structure of bacterorhodopsin mutant A51P | Descriptor: | Bacteriorhodopsin, RETINAL | Authors: | Yohannan, S, Yang, D, Faham, S, Boulting, G, Whitelegge, J, Bowie, J.U. | Deposit date: | 2004-06-11 | Release date: | 2004-10-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Proline substitutions are not easily accommodated in a membrane protein J.Mol.Biol., 341, 2004
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3LKW
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![BU of 3lkw by Molmil](/molmil-images/mine/3lkw) | Crystal Structure of Dengue Virus 1 NS2B/NS3 protease active site mutant | Descriptor: | CADMIUM ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Chandramouli, S, Joseph, J.S, Daudenarde, S, Gatchalian, J, Cornillez-Ty, C, Kuhn, P. | Deposit date: | 2010-01-28 | Release date: | 2010-03-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Serotype-specific structural differences in the protease-cofactor complexes of the dengue virus family. J.Virol., 84, 2010
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3L6P
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![BU of 3l6p by Molmil](/molmil-images/mine/3l6p) | Crystal Structure of Dengue Virus 1 NS2B/NS3 protease | Descriptor: | CADMIUM ION, NICKEL (II) ION, SULFATE ION, ... | Authors: | Chandramouli, S, Joseph, J.S, Daudenarde, S, Gatchalian, J, Cornillez-Ty, C, Kuhn, P. | Deposit date: | 2009-12-23 | Release date: | 2010-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Serotype-specific structural differences in the protease-cofactor complexes of the dengue virus family. J.Virol., 84, 2010
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1SE2
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![BU of 1se2 by Molmil](/molmil-images/mine/1se2) | |
2J7K
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![BU of 2j7k by Molmil](/molmil-images/mine/2j7k) | Crystal structure of the T84A mutant EF-G:GDPCP complex | Descriptor: | ELONGATION FACTOR G, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | Authors: | Hansson, S, Logan, D.T. | Deposit date: | 2006-10-12 | Release date: | 2007-10-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | New Insights Into the Role of the P-Loop Lysine: Implications from the Crystal Structure of a Mutant EF-G:Gdpcp Complex To be Published
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4H5S
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![BU of 4h5s by Molmil](/molmil-images/mine/4h5s) | Complex structure of Necl-2 and CRTAM | Descriptor: | Cell adhesion molecule 1, Cytotoxic and regulatory T-cell molecule | Authors: | Zhang, S, Lu, G, Qi, J, Li, Y, Zhang, Z, Zhang, B, Yan, J, Gao, G.F. | Deposit date: | 2012-09-18 | Release date: | 2013-08-07 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Competition of cell adhesion and immune recognition: insights into the interaction between CRTAM and nectin-like 2. Structure, 21, 2013
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1YM2
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![BU of 1ym2 by Molmil](/molmil-images/mine/1ym2) | Crystal structure of human beta secretase complexed with NVP-AUR200 | Descriptor: | Beta-secretase 1, NVP-AUR200 INHIBITOR | Authors: | Hanessian, S, Yun, H, Hou, Y, Yang, G, Bayrakdarian, M, Therrien, E, Moitessier, N, Roggo, S, Veenstra, S. | Deposit date: | 2005-01-20 | Release date: | 2006-01-17 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics J.Med.Chem., 48, 2005
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5IOO
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![BU of 5ioo by Molmil](/molmil-images/mine/5ioo) | Accommodation of massive sequence variation in Nanoarchaeota by the C-type lectin fold | Descriptor: | AvpA, MAGNESIUM ION | Authors: | Handa, S, Paul, B, Miller, J, Valentine, D, Ghosh, P. | Deposit date: | 2016-03-08 | Release date: | 2016-11-09 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (2.521 Å) | Cite: | Conservation of the C-type lectin fold for accommodating massive sequence variation in archaeal diversity-generating retroelements. Bmc Struct.Biol., 16, 2016
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2BM0
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![BU of 2bm0 by Molmil](/molmil-images/mine/2bm0) | Ribosomal elongation factor G (EF-G) Fusidic acid resistant mutant T84A | Descriptor: | ELONGATION FACTOR G, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Hansson, S, Singh, R, Gudkov, A.T, Liljas, A, Logan, D.T. | Deposit date: | 2005-03-09 | Release date: | 2005-05-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Insights Into Fusidic Acid Resistance and Sensitivity in EF-G J.Mol.Biol., 348, 2005
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2BM1
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![BU of 2bm1 by Molmil](/molmil-images/mine/2bm1) | Ribosomal elongation factor G (EF-G) Fusidic acid resistant mutant G16V | Descriptor: | ELONGATION FACTOR G, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Hansson, S, Singh, R, Gudkov, A.T, Liljas, A, Logan, D.T. | Deposit date: | 2005-03-09 | Release date: | 2005-05-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Insights Into Fusidic Acid Resistance and Sensitivity in EF-G J.Mol.Biol., 348, 2005
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1YM4
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![BU of 1ym4 by Molmil](/molmil-images/mine/1ym4) | Crystal structure of human beta secretase complexed with NVP-AMK640 | Descriptor: | Beta-secretase 1, NVP-AMK640 INHIBITOR | Authors: | Hanessian, S, Yun, H, Hou, Y, Yang, G, Bayrakdarian, M, Therrien, E, Moitessier, N, Roggo, S, Veenstra, S. | Deposit date: | 2005-01-20 | Release date: | 2006-01-17 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics J.Med.Chem., 48, 2005
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5JYP
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![BU of 5jyp by Molmil](/molmil-images/mine/5jyp) | Allosteric inhibition of Kidney Isoform of Glutaminase | Descriptor: | 2-phenyl-~{N}-[5-[(1~{S},3~{S})-3-[5-(2-phenylethanoylamino)-1,3,4-thiadiazol-2-yl]cyclohexyl]-1,3,4-thiadiazol-2-yl]ethanamide, Glutaminase kidney isoform, mitochondrial | Authors: | Ramachandran, S, Sivaraman, J. | Deposit date: | 2016-05-15 | Release date: | 2016-08-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | Structural basis for exploring the allosteric inhibition of human kidney type glutaminase. Oncotarget, 7, 2016
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5KW9
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![BU of 5kw9 by Molmil](/molmil-images/mine/5kw9) | |