8PTM
| Structure of the transcription termination factor Rho in complex with Rof and ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein rof, ... | Authors: | Said, N, Hilal, T, Wahl, M.C. | Deposit date: | 2023-07-14 | Release date: | 2024-04-17 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Sm-like protein Rof inhibits transcription termination factor rho by binding site obstruction and conformational insulation. Nat Commun, 15, 2024
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8PTN
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8PTG
| Structure of the transcription termination factor Rho bound to RNA at the PBS and SBS | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | Authors: | Said, N, Hilal, T, Wahl, M.C. | Deposit date: | 2023-07-14 | Release date: | 2024-04-17 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Sm-like protein Rof inhibits transcription termination factor rho by binding site obstruction and conformational insulation. Nat Commun, 15, 2024
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6ET8
| Crystal structure of AlbA in complex with albicidin | Descriptor: | Albicidin resistance protein, SULFATE ION, albicidin | Authors: | Driller, R, Rostock, L, Alings, C, Graetz, S, Suessmuth, R, Mainz, A, Wahl, M.C, Loll, B. | Deposit date: | 2017-10-25 | Release date: | 2018-08-15 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Molecular insights into antibiotic resistance - how a binding protein traps albicidin. Nat Commun, 9, 2018
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6F4H
| Crystal structure of the Drosophila melanogaster SNF/U1-SL2 complex | Descriptor: | CITRATE ANION, U1 small nuclear ribonucleoprotein A, U1-SL2 | Authors: | Weber, G, Holton, N, Hall, K.B, DeKoster, G, Wahl, M.C. | Deposit date: | 2017-11-29 | Release date: | 2018-06-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular principles underlying dual RNA specificity in the Drosophila SNF protein. Nat Commun, 9, 2018
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6EUD
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6F4G
| 'Crystal structure of the Drosophila melanogaster SNF/U2A'/U2-SL4 complex | Descriptor: | CHLORIDE ION, Probable U2 small nuclear ribonucleoprotein A', SULFATE ION, ... | Authors: | Weber, G, DeKoster, G, Holton, N, Hall, K.B, Wahl, M.C. | Deposit date: | 2017-11-29 | Release date: | 2018-06-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular principles underlying dual RNA specificity in the Drosophila SNF protein. Nat Commun, 9, 2018
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1PZW
| Crystal structure of the zinc finger associated domain of the Drosophila transcription factor Grauzone | Descriptor: | Transcription factor grauzone, ZINC ION | Authors: | Jauch, R, Bourenkov, G.P, Chung, H.-R, Urlaub, H, Reidt, U, Jaeckle, H, Wahl, M.C. | Deposit date: | 2003-07-14 | Release date: | 2003-11-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The zinc finger-associated domain of the Drosophila transcription factor grauzone is a novel zinc-coordinating protein-protein interaction module STRUCTURE, 11, 2003
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6S8Q
| Human Brr2 Helicase Region in complex with C-tail deleted Jab1 | Descriptor: | Pre-mRNA-processing-splicing factor 8, SULFATE ION, U5 small nuclear ribonucleoprotein 200 kDa helicase | Authors: | Santos, K.F, Vester, K, Wahl, M.C. | Deposit date: | 2019-07-10 | Release date: | 2020-01-22 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.391 Å) | Cite: | The inactive C-terminal cassette of the dual-cassette RNA helicase BRR2 both stimulates and inhibits the activity of the N-terminal helicase unit. J.Biol.Chem., 295, 2020
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6S9I
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6F4J
| Crystal structure of Drosophila melanogaster SNF/U2A' complex | Descriptor: | POLYETHYLENE GLYCOL (N=34), Probable U2 small nuclear ribonucleoprotein A', SULFATE ION, ... | Authors: | Weber, G, DeKoster, G, Holton, N, Hall, K.B, Wahl, M.C. | Deposit date: | 2017-11-29 | Release date: | 2018-06-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Molecular principles underlying dual RNA specificity in the Drosophila SNF protein. Nat Commun, 9, 2018
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6S8O
| Human Brr2 Helicase Region M641C/A1582C | Descriptor: | U5 small nuclear ribonucleoprotein 200 kDa helicase | Authors: | Vester, K, Santos, K.F, Wahl, M.C. | Deposit date: | 2019-07-10 | Release date: | 2020-01-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.172 Å) | Cite: | The inactive C-terminal cassette of the dual-cassette RNA helicase BRR2 both stimulates and inhibits the activity of the N-terminal helicase unit. J.Biol.Chem., 295, 2020
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6F4I
| Crystal structure of Drosophila melanogaster SNF | Descriptor: | U1 small nuclear ribonucleoprotein A | Authors: | Weber, G, Holton, N, Hall, K.B, DeKoster, G, Wahl, M.C. | Deposit date: | 2017-11-29 | Release date: | 2018-06-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Molecular principles underlying dual RNA specificity in the Drosophila SNF protein. Nat Commun, 9, 2018
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1N8P
| Crystal Structure of cystathionine gamma-lyase from yeast | Descriptor: | Cystathionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Messerschmidt, A, Worbs, M, Steegborn, C, Wahl, M.C, Huber, R, Clausen, T. | Deposit date: | 2002-11-21 | Release date: | 2002-12-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Determinants of Enzymatic Specificity in the Cys-Met-Metabolism PLP-Dependent Enzymes Family: Crystal Structure of Cystathionine gamma-lyase from Yeast and Intrafamiliar Structural Comparison BIOL.CHEM., 384, 2003
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6TQO
| rrn anti-termination complex | Descriptor: | 30S ribosomal protein S10, 30S ribosomal protein S4, DNA-directed RNA polymerase subunit alpha, ... | Authors: | Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N. | Deposit date: | 2019-12-17 | Release date: | 2020-08-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis. Mol.Cell, 79, 2020
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6GOV
| Structure of THE RNA POLYMERASE LAMBDA-BASED ANTITERMINATION COMPLEX | Descriptor: | 30S ribosomal protein S10, Antitermination protein N, DNA (I), ... | Authors: | Loll, B, Krupp, F, Said, N, Huang, Y, Buerger, J, Mielke, T, Spahn, C.M.T, Wahl, M.C. | Deposit date: | 2018-06-04 | Release date: | 2019-02-13 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor. Mol.Cell, 74, 2019
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6TQN
| rrn anti-termination complex without S4 | Descriptor: | 30S ribosomal protein S10, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N. | Deposit date: | 2019-12-17 | Release date: | 2020-08-05 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis. Mol.Cell, 79, 2020
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6H5T
| Intersectin SH3A short isoform | Descriptor: | 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL, ACETATE ION, CHLORIDE ION, ... | Authors: | Driller, J.H, Gerth, F, Freund, C, Wahl, M.C, Loll, B. | Deposit date: | 2018-07-25 | Release date: | 2019-02-27 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.689 Å) | Cite: | Exon Inclusion Modulates Conformational Plasticity and Autoinhibition of the Intersectin 1 SH3A Domain. Structure, 27, 2019
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1DMG
| CRYSTAL STRUCTURE OF RIBOSOMAL PROTEIN L4 | Descriptor: | CITRIC ACID, RIBOSOMAL PROTEIN L4 | Authors: | Worbs, M, Huber, R, Wahl, M.C. | Deposit date: | 1999-12-14 | Release date: | 2000-12-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of ribosomal protein L4 shows RNA-binding sites for ribosome incorporation and feedback control of the S10 operon. EMBO J., 19, 2000
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6TEO
| Crystal structure of a yeast Snu114-Prp8 complex | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-splicing factor 8, ... | Authors: | Ganichkin, O, Jia, J, Loll, B, Absmeier, E, Wahl, M.C. | Deposit date: | 2019-11-12 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | A Snu114-GTP-Prp8 module forms a relay station for efficient splicing in yeast. Nucleic Acids Res., 48, 2020
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6TW2
| Re-refined crystal structure of di-phosphorylated human CLK1 in complex with a novel substituted indole inhibitor | Descriptor: | Dual specificity protein kinase CLK1, ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate | Authors: | Loll, B, Haltenhof, T, Heyd, F, Wahl, M.C. | Deposit date: | 2020-01-12 | Release date: | 2020-02-05 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Conserved Kinase-Based Body-Temperature Sensor Globally Controls Alternative Splicing and Gene Expression. Mol.Cell, 78, 2020
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2LQ8
| Domain interaction in Thermotoga maritima NusG | Descriptor: | Transcription antitermination protein nusG | Authors: | Droegemueller, J, Stegmann, C, Burmann, B, Roesch, P, Wahl, M.C, Schweimer, K. | Deposit date: | 2012-02-27 | Release date: | 2013-01-23 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | An Autoinhibited State in the Structure of Thermotoga maritima NusG. Structure, 21, 2013
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3LS3
| Padron0.9-ON (fluorescent state) | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Padron0.9, ... | Authors: | Brakemann, T, Weber, G, Trowitzsch, S, Wahl, M.C, Jakobs, S. | Deposit date: | 2010-02-12 | Release date: | 2010-03-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Molecular basis of the light-driven switching of the photochromic fluorescent protein Padron. J.Biol.Chem., 285, 2010
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2MKC
| Cooperative Structure of the Heterotrimeric pre-mRNA Retention and Splicing Complex | Descriptor: | Pre-mRNA leakage protein 1, Pre-mRNA-splicing factor CWC26, U2 snRNP component IST3 | Authors: | Wysoczanski, P, Schneider, C, Xiang, S, Munari, F, Trowitzsch, S, Wahl, M.C, Luhrmann, R, Becker, S, Zweckstetter, M. | Deposit date: | 2014-02-04 | Release date: | 2014-09-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Cooperative structure of the heterotrimeric pre-mRNA retention and splicing complex. Nat.Struct.Mol.Biol., 21, 2014
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2OZB
| Structure of a human Prp31-15.5K-U4 snRNA complex | Descriptor: | CALCIUM ION, RNA comprising the 5' Stem-Loop RNA of U4snRNA, U4/U6 small nuclear ribonucleoprotein Prp31, ... | Authors: | Liu, S, Luehrmann, R, Wahl, M.C. | Deposit date: | 2007-02-26 | Release date: | 2007-03-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP. Science, 316, 2007
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