Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
2CI0
DownloadVisualize
BU of 2ci0 by Molmil
High throughput screening and x-ray crystallography assisted evaluation of small molecule scaffolds for CYP51 inhibitors
Descriptor: (2R)-2-PHENYL-N-PYRIDIN-4-YLBUTANAMIDE, CYTOCHROME P450 51, PROTOPORPHYRIN IX CONTAINING FE
Authors:Podust, L.M, Kim, Y, Yermalitskaya, L.V, Von Kries, J.P, Waterman, M.R.
Deposit date:2006-03-16
Release date:2007-07-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Small Molecule Scaffolds for Cyp51 Inhibitors Identified by High Throughput Screening and Defined by X-Ray Crystallography
Antimicrob.Agents Chemother., 51, 2007
1BTN
DownloadVisualize
BU of 1btn by Molmil
STRUCTURE OF THE BINDING SITE FOR INOSITOL PHOSPHATES IN A PH DOMAIN
Descriptor: BETA-SPECTRIN, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE
Authors:Wilmanns, M, Hyvoenen, M, Saraste, M.
Deposit date:1995-08-23
Release date:1996-03-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the binding site for inositol phosphates in a PH domain.
EMBO J., 14, 1995
3CTI
DownloadVisualize
BU of 3cti by Molmil
RELAXATION MATRIX REFINEMENT OF THE SOLUTION STRUCTURE OF SQUASH TRYPSIN INHIBITOR
Descriptor: TRYPSIN INHIBITOR
Authors:Nilges, M, Habazettl, J, Bruenger, A.T, Holak, T.A.
Deposit date:1991-03-27
Release date:1992-04-15
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Relaxation matrix refinement of the solution structure of squash trypsin inhibitor.
J.Mol.Biol., 219, 1991
2M3U
DownloadVisualize
BU of 2m3u by Molmil
Solution-state NMR structure of cataract-related human gamma(S)-crystallin point variant G18V
Descriptor: Beta-crystallin S
Authors:Brubaker, W.D, Martin, R.W.
Deposit date:2013-01-25
Release date:2013-11-13
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Preferential and Specific Binding of Human alpha B-Crystallin to a Cataract-Related Variant of gamma S-Crystallin.
Structure, 21, 2013
2M3T
DownloadVisualize
BU of 2m3t by Molmil
Solution-state NMR structure of wild-type human gamma(S)-crystallin
Descriptor: Beta-crystallin S
Authors:Brubaker, W.D, Martin, R.W.
Deposit date:2013-01-25
Release date:2013-11-13
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Preferential and Specific Binding of Human alpha B-Crystallin to a Cataract-Related Variant of gamma S-Crystallin.
Structure, 21, 2013
5NCF
DownloadVisualize
BU of 5ncf by Molmil
ENAH EVH1 in complex with Ac-[2-Cl-F]-[ProM-2]-[ProM-4]-OH
Descriptor: (1~{S},4~{S},7~{R},10~{R})-14-[(3~{S},6~{R},8~{a}~{S})-1'-[(2~{S})-2-acetamido-3-(2-chlorophenyl)propanoyl]-5-oxidanylidene-spiro[1,2,3,8~{a}-tetrahydroindolizine-6,2'-pyrrolidine]-3-yl]carbonyl-2-oxidanylidene-3,14-diazatricyclo[8.4.0.0^{3,7}]tetradec-8-ene-4-carboxylic acid, GLYCEROL, NITRATE ION, ...
Authors:Barone, M, Roske, Y.
Deposit date:2017-03-04
Release date:2017-06-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
5N9P
DownloadVisualize
BU of 5n9p by Molmil
ENAH EVH1 in complex with Ac-[2-Cl-F]-PP-[ProM-1]-NH2
Descriptor: Ac-[2-Cl-F]-PP-[ProM-1]-NH2, CHLORIDE ION, Protein enabled homolog
Authors:Barone, M, Roske, Y.
Deposit date:2017-02-26
Release date:2017-06-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
5N9C
DownloadVisualize
BU of 5n9c by Molmil
ENAH EVH1 in complex with Ac-[2-Cl-F]-PP-[ProM-1]-OH
Descriptor: Ac-[2-Cl-F]-PP-[ProM-1]-OH, GLYCEROL, NITRATE ION, ...
Authors:Barone, M, Roske, Y.
Deposit date:2017-02-24
Release date:2017-06-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
1PPB
DownloadVisualize
BU of 1ppb by Molmil
THE REFINED 1.9 ANGSTROMS CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN: INTERACTION WITH D-PHE-PRO-ARG CHLOROMETHYLKETONE AND SIGNIFICANCE OF THE TYR-PRO-PRO-TRP INSERTION SEGMENT
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide
Authors:Bode, W.
Deposit date:1991-10-24
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment.
EMBO J., 8, 1989
2KD3
DownloadVisualize
BU of 2kd3 by Molmil
NMR structure of the Wnt modulator protein Sclerostin
Descriptor: Sclerostin
Authors:Weidauer, S.E, Mueller, T.D.
Deposit date:2009-01-02
Release date:2009-02-10
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:NMR structure of the Wnt modulator protein Sclerostin
Biochem.Biophys.Res.Commun., 380, 2009
1CEW
DownloadVisualize
BU of 1cew by Molmil
THE 2.0 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF CHICKEN EGG WHITE CYSTATIN AND ITS POSSIBLE MODE OF INTERACTION WITH CYSTEINE PROTEINASES
Descriptor: CYSTATIN
Authors:Bode, W, Musil, D, Huber, R.
Deposit date:1993-04-21
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases.
EMBO J., 7, 1988
1DWC
DownloadVisualize
BU of 1dwc by Molmil
CRYSTALLOGRAPHIC ANALYSIS AT 3.0-ANGSTROMS RESOLUTION OF THE BINDING TO HUMAN THROMBIN OF FOUR ACTIVE SITE-DIRECTED INHIBITORS
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), HIRUDIN IIIA, ...
Authors:Banner, D.W, Hadvary, P.
Deposit date:1992-08-19
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors.
J.Biol.Chem., 266, 1991
1DWD
DownloadVisualize
BU of 1dwd by Molmil
CRYSTALLOGRAPHIC ANALYSIS AT 3.0-ANGSTROMS RESOLUTION OF THE BINDING TO HUMAN THROMBIN OF FOUR ACTIVE SITE-DIRECTED INHIBITORS
Descriptor: 1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimidoyl-D-phenylalanyl]piperidine, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ...
Authors:Banner, D.W, Hadvary, P.
Deposit date:1992-08-19
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors.
J.Biol.Chem., 266, 1991
1DWE
DownloadVisualize
BU of 1dwe by Molmil
Crystallographic analysis at 3.0-Angstroms resolution of the binding to human thrombin of four active site-directed inhibitors
Descriptor: ALPHA-THROMBIN heavy chain, ALPHA-THROMBIN light chain, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ...
Authors:Banner, D.W, Hadvary, P.
Deposit date:1992-08-19
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors.
J.Biol.Chem., 266, 1991
1DWB
DownloadVisualize
BU of 1dwb by Molmil
CRYSTALLOGRAPHIC ANALYSIS AT 3.0-ANGSTROMS RESOLUTION OF THE BINDING TO HUMAN THROMBIN OF FOUR ACTIVE SITE-DIRECTED INHIBITORS
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), BENZAMIDINE, ...
Authors:Banner, D.W, Hadvary, P.
Deposit date:1992-08-19
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors.
J.Biol.Chem., 266, 1991
2JM5
DownloadVisualize
BU of 2jm5 by Molmil
Solution Structure of the RGS domain from human RGS18
Descriptor: Regulator of G-protein signaling 18
Authors:Higman, V.A, Leidert, M, Bray, J, Elkins, J, Soundararajan, M, Doyle, D.A, Gileadi, C, Phillips, C, Schoch, G, Yang, X, Brockmann, C, Schmieder, P, Diehl, A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Oschkinat, H, Ball, L.J, Structural Genomics Consortium (SGC)
Deposit date:2006-10-11
Release date:2006-10-24
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1DE7
DownloadVisualize
BU of 1de7 by Molmil
INTERACTION OF FACTOR XIII ACTIVATION PEPTIDE WITH ALPHA-THROMBIN: CRYSTAL STRUCTURE OF THE ENZYME-SUBSTRATE COMPLEX
Descriptor: ALPHA-THROMBIN (HEAVY CHAIN), ALPHA-THROMBIN (LIGHT CHAIN), FACTOR XIII ACTIVATION PEPTIDE (28-37), ...
Authors:Sadasivan, C, Yee, V.C.
Deposit date:1999-11-13
Release date:2000-12-13
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interaction of the factor XIII activation peptide with alpha -thrombin. Crystal structure of its enzyme-substrate analog complex.
J.Biol.Chem., 275, 2000
1PVW
DownloadVisualize
BU of 1pvw by Molmil
3,4-dihydroxy-2-butanone 4-phosphate synthase from M. jannaschii
Descriptor: 3,4-dihydroxy-2-butanone 4-phosphate synthase, CALCIUM ION, PHOSPHATE ION, ...
Authors:Steinbacher, S, Schiffmann, S, Richter, G, Huber, R, Bacher, A, Fischer, M.
Deposit date:2003-06-29
Release date:2003-11-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure of 3,4-Dihydroxy-2-butanone 4-Phosphate Synthase from Methanococcus jannaschii in Complex with Divalent Metal Ions and the Substrate Ribulose 5-Phosphate: IMPLICATIONS FOR THE CATALYTIC MECHANISM
J.Biol.Chem., 278, 2003
1PVY
DownloadVisualize
BU of 1pvy by Molmil
3,4-dihydroxy-2-butanone 4-phosphate synthase from M. jannaschii in complex with ribulose 5-phosphate
Descriptor: 3,4-dihydroxy-2-butanone 4-phosphate synthase, CALCIUM ION, RIBULOSE-5-PHOSPHATE, ...
Authors:Steinbacher, S, Schiffmann, S, Richter, G, Huber, R, Bacher, A, Fischer, M.
Deposit date:2003-06-29
Release date:2003-11-04
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of 3,4-Dihydroxy-2-butanone 4-Phosphate Synthase from Methanococcus jannaschii in Complex with Divalent Metal Ions and the Substrate Ribulose 5-Phosphate: IMPLICATIONS FOR THE CATALYTIC MECHANISM
J.Biol.Chem., 278, 2003
1HIJ
DownloadVisualize
BU of 1hij by Molmil
INTERLEUKIN-4 MUTANT WITH ARG 88 REPLACED WITH GLN (R88Q)
Descriptor: INTERLEUKIN-4
Authors:Mueller, T, Buehner, M.
Deposit date:1995-06-01
Release date:1996-01-29
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Human interleukin-4 and variant R88Q: phasing X-ray diffraction data by molecular replacement using X-ray and nuclear magnetic resonance models.
J.Mol.Biol., 247, 1995
1HIK
DownloadVisualize
BU of 1hik by Molmil
INTERLEUKIN-4 (WILD-TYPE)
Descriptor: INTERLEUKIN-4
Authors:Mueller, T, Buehner, M.
Deposit date:1995-06-01
Release date:1996-01-29
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Human interleukin-4 and variant R88Q: phasing X-ray diffraction data by molecular replacement using X-ray and nuclear magnetic resonance models.
J.Mol.Biol., 247, 1995
2I59
DownloadVisualize
BU of 2i59 by Molmil
Solution structure of RGS10
Descriptor: Regulator of G-protein signaling 10
Authors:Fedorov, O, Higman, V.A, Diehl, A, Leidert, M, Lemak, A, Schmieder, P, Oschkinat, H, Elkins, J, Soundarajan, M, Doyle, D.A, Arrowsmith, C, Sundstrom, M, Weigelt, J, Edwards, A, Ball, L.J, Structural Genomics Consortium (SGC)
Deposit date:2006-08-24
Release date:2006-10-31
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2JNU
DownloadVisualize
BU of 2jnu by Molmil
Solution structure of the RGS domain of human RGS14
Descriptor: Regulator of G-protein signaling 14
Authors:Dowler, E.F, Diehl, A, Bray, J, Elkins, J, Soundararajan, M, Doyle, D.A, Gileadi, C, Phillips, C, Schoch, G.A, Yang, X, Brockmann, C, Leidert, M, Rehbein, K, Schmieder, P, Kuhne, R, Higman, V.A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Oschkinat, H, Ball, L.J, Structural Genomics Consortium (SGC)
Deposit date:2007-02-02
Release date:2007-02-27
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008

221051

PDB entries from 2024-06-12

PDB statisticsPDBj update infoContact PDBjnumon