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2L6T
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BU of 2l6t by Molmil
Efficacy of an HIV-1 entry inhibitor targeting the GP41 fusion peptide
Descriptor: VIR-576
Authors:Forssmann, W, The, Y, Stoll, M, Adermann, K, Albrecht, U, Barlos, K, Busmann, A, Can les-Mayordomo, A, Gimenez-Gallego, G, Hirsch, J, Jimenez-Barbero, J, Meyer-Olson, D, Muench, J, Perez-Castells, J, Staendker, L, Kirchhoff, F, Schmidt, R.E.
Deposit date:2010-11-24
Release date:2011-01-19
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide.
Sci Transl Med, 2, 2010
2LHL
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BU of 2lhl by Molmil
Chemical Shift Assignments and solution structure of human apo-S100A1 E32Q mutant
Descriptor: Protein S100-A1
Authors:Ruszczynska-Bartnik, K, Zdanowski, K, Zhukov, I, Bierzynski, A, Ejchart, A.
Deposit date:2011-08-12
Release date:2012-08-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:1H, 13C and 15N NMR sequence-specific resonance assignments and relaxation parameters for human apo-S100A1 E32Q mutant
To be Published
2LP3
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BU of 2lp3 by Molmil
Solution structure of S100A1 Ca2+
Descriptor: CALCIUM ION, Protein S100-A1
Authors:Budzinska, M, Ruszczynska-Bartnik, K, Belczyk-Ciesielska, A, Bierzynski, A, Ejchart, A.
Deposit date:2012-01-31
Release date:2013-02-20
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Impact of calcium binding and thionylation of S100A1 protein on its nuclear magnetic resonance-derived structure and backbone dynamics.
Biochemistry, 52, 2013
2LUX
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BU of 2lux by Molmil
Calcium saturated form of human C85M S100A1 mutant
Descriptor: CALCIUM ION, Protein S100-A1
Authors:Ruszczynska-Bartnik, K, Budzinska, M, Zdanowski, K, Ejchart, A.
Deposit date:2012-06-22
Release date:2013-06-26
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of human holo-S100A1 C85M mutant
To be Published
2M3W
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BU of 2m3w by Molmil
Protein structure determination from a set of 4D NOESY
Descriptor: Protein S100-A1
Authors:Nowakowski, M.E, Stanek, J, Ruszczynska-Bartnik, K, Ejchart, A.O, Kozminski, W.
Deposit date:2013-01-28
Release date:2014-03-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Determination of protein structure from a set of 4D NOESY performed with non uniform sampling
To be Published
5OH6
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BU of 5oh6 by Molmil
Legionella pneumophila RidL N-terminal domain lacking beta hairpin
Descriptor: Interaptin
Authors:Baerlocher, K, Hutter, C.A.J, Swart, A.L, Steiner, B, Welin, A, Hohl, M, Letourneur, F, Seeger, M.A, Hilbi, H.
Deposit date:2017-07-14
Release date:2017-11-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural insights into Legionella RidL-Vps29 retromer subunit interaction reveal displacement of the regulator TBC1D5.
Nat Commun, 8, 2017
5OH5
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BU of 5oh5 by Molmil
Legionella pneumophila RidL N-terminal retromer binding domain
Descriptor: RidL
Authors:Baerlocher, K, Hutter, C.A.J, Swart, A.L, Steiner, B, Welin, A, Hohl, M, Letourneur, F, Seeger, M.A, Hilbi, H.
Deposit date:2017-07-14
Release date:2017-11-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into Legionella RidL-Vps29 retromer subunit interaction reveal displacement of the regulator TBC1D5.
Nat Commun, 8, 2017
4ACP
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BU of 4acp by Molmil
Deactivation of human IgG1 Fc by endoglycosidase treatment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, IG GAMMA-1 CHAIN C REGION
Authors:Raman, K, Bowden, T.A, Krishna, B.A, Dwek, R.A, Crispin, M, Scanlan, C.N.
Deposit date:2011-12-16
Release date:2012-04-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Selective Deactivation of Serum Igg: A General Strategy for the Enhancement of Monoclonal Antibody Receptor Interactions.
J.Mol.Biol., 420, 2012
3LTQ
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BU of 3ltq by Molmil
Structure of Interleukin 1B solved by SAD using an inserted Lanthanide Binding Tag
Descriptor: ACETATE ION, Interleukin-1 beta, SULFATE ION, ...
Authors:Peisach, E, Allen, K.N.
Deposit date:2010-02-16
Release date:2011-02-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Engineering encodable lanthanide-binding tags into loop regions of proteins.
J.Am.Chem.Soc., 133, 2011
2RDF
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BU of 2rdf by Molmil
Crystal Structure of staphyloccocal nuclease VIAGAN/E75A variant at cryogenic temperature
Descriptor: PHOSPHATE ION, Thermonuclease
Authors:Baran, K, Schlessman, J.L, Garcia-Moreno, B.E.
Deposit date:2007-09-22
Release date:2008-06-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Electrostatic effects in a network of polar and ionizable groups in staphylococcal nuclease.
J.Mol.Biol., 379, 2008
1A3P
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BU of 1a3p by Molmil
ROLE OF THE 6-20 DISULFIDE BRIDGE IN THE STRUCTURE AND ACTIVITY OF EPIDERMAL GROWTH FACTOR, NMR, 20 STRUCTURES
Descriptor: EPIDERMAL GROWTH FACTOR
Authors:Barnham, K, Torres, A, Alewood, D, Alewood, P, Domagala, T, Nice, E, Norton, R.
Deposit date:1998-01-22
Release date:1998-07-29
Last modified:2018-03-14
Method:SOLUTION NMR
Cite:Role of the 6-20 disulfide bridge in the structure and activity of epidermal growth factor.
Protein Sci., 7, 1998
6H9M
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BU of 6h9m by Molmil
Coiled-coil domain-containing protein 90B residues 43-125 from Homo sapiens fused to a GCN4 adaptor
Descriptor: Coiled-coil domain-containing protein 90B, mitochondrial,General control protein GCN4
Authors:Adlakha, J, Albrecht, R, Lupas, A.N, Hernandez Alvarez, B, Hartmann, M.D.
Deposit date:2018-08-04
Release date:2019-02-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Characterization of MCU-Binding Proteins MCUR1 and CCDC90B - Representatives of a Protein Family Conserved in Prokaryotes and Eukaryotic Organelles.
Structure, 27, 2019
6R0V
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BU of 6r0v by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with hydrolysis product of compound 4b
Descriptor: 2-[[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamoyl]-4-nitro-benzoic acid, CHLORIDE ION, Cereblon isoform 4, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-13
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R0U
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BU of 6r0u by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 5a and hydrolysis product
Descriptor: 3-azanyl-2-[[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamoyl]benzoic acid, 4-azanyl-2-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]isoindole-1,3-dione, CHLORIDE ION, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-13
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R0S
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BU of 6r0s by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 4a and hydrolysis product
Descriptor: 2-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]-4-nitro-isoindole-1,3-dione, 2-[[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamoyl]-6-nitro-benzoic acid, CEREBLON ISOFORM 4, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-13
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R0Q
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BU of 6r0q by Molmil
Mutant cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with thalidomide metabolite alpha-(o-carboxybenzamido)glutarimide
Descriptor: 2-[[(3~{S})-2,6-bis(oxidanylidene)piperidin-3-yl]carbamoyl]benzoic acid, ALA-ALA-ALA, ALA-ALA-ALA-ALA, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-13
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R11
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BU of 6r11 by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 5b
Descriptor: 5-azanyl-2-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]isoindole-1,3-dione, CHLORIDE ION, Cereblon isoform 4, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-13
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R13
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BU of 6r13 by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 7f
Descriptor: CHLORIDE ION, Cereblon isoform 4, PHOSPHATE ION, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-13
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R12
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BU of 6r12 by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 7b
Descriptor: CHLORIDE ION, Cereblon isoform 4, PHOSPHATE ION, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-13
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R18
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BU of 6r18 by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 11a
Descriptor: CHLORIDE ION, Cereblon isoform 4, PHOSPHATE ION, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-14
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R19
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BU of 6r19 by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 20a
Descriptor: Cereblon isoform 4, PHOSPHATE ION, S-Thalidomide, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-14
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R1A
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BU of 6r1a by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 20b
Descriptor: Cereblon isoform 4, PHOSPHATE ION, S-Thalidomide, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-14
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6H9L
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BU of 6h9l by Molmil
Kcr_0859 delta TM from Korarchaeum cryptofilum
Descriptor: Uncharacterized protein
Authors:Hartmann, M.D, Lupas, A.N, Hernandez Alvarez, B.
Deposit date:2018-08-04
Release date:2019-02-13
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Characterization of MCU-Binding Proteins MCUR1 and CCDC90B - Representatives of a Protein Family Conserved in Prokaryotes and Eukaryotic Organelles.
Structure, 27, 2019
6R1D
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BU of 6r1d by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 7d, co-crystallized
Descriptor: (phenylmethyl) ~{N}-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamate, Cereblon isoform 4, ZINC ION
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-14
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019
6R1K
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BU of 6r1k by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 7c
Descriptor: Cereblon isoform 4, PHOSPHATE ION, ZINC ION, ...
Authors:Heim, C, Hartmann, M.D.
Deposit date:2019-03-14
Release date:2019-08-07
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives.
J.Med.Chem., 62, 2019

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