6R0S

Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 4a and hydrolysis product

Summary for 6R0S

Entry DOI	10.2210/pdb6r0s/pdb
Descriptor	Cereblon isoform 4, CEREBLON ISOFORM 4, ZINC ION, ... (9 entities in total)
Functional Keywords	----, signaling protein
Biological source	Magnetospirillum gryphiswaldense MSR-1 More
Total number of polymer chains	4
Total formula weight	42660.33
Authors	Heim, C.,Hartmann, M.D. (deposition date: 2019-03-13, release date: 2019-08-07, Last modification date: 2024-01-24)
Primary citation	Heim, C.,Pliatsika, D.,Mousavizadeh, F.,Bar, K.,Hernandez Alvarez, B.,Giannis, A.,Hartmann, M.D. De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives. J.Med.Chem., 62:6615-6629, 2019 Cited by PubMed: 31251063 DOI: 10.1021/acs.jmedchem.9b00454 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation