6R0S
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 4a and hydrolysis product
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Cereblon isoform 4 | polymer | 125 | 13703.6 | 3 | UniProt (A4TVL0) | Magnetospirillum gryphiswaldense MSR-1 | |
| 2 | D (F) | CEREBLON ISOFORM 4 | polymer | 3 | 273.3 | 1 | Magnetospirillum gryphiswaldense MSR-1 | ||
| 3 | E, H, L (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 4 | F (A) | S-Thalidomide | non-polymer | 258.2 | 1 | Chemie (EF2) | |||
| 5 | G, J (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 6 | I (B) | 2-[[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]carbamoyl]-6-nitro-benzoic acid | non-polymer | 307.2 | 1 | Chemie (JOE) | |||
| 7 | K (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 8 | M (C) | 2-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]-4-nitro-isoindole-1,3-dione | non-polymer | 289.2 | 1 | Chemie (JOH) | |||
| 9 | N, O, P (A, B, C) | water | water | 18.0 | 223 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 124 (UniProt: A4TVL0)
| PDB | External Database | Details |
|---|---|---|
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 41384.1 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1276.3 | |
| All* | Total formula weight | 42660.3 |
