7VUE
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![BU of 7vue by Molmil](/molmil-images/mine/7vue) | Structural insight of the molecular mechanism of cilofexor bound to FXR | Descriptor: | 2-[3-[4-[[3-[2,6-bis(chloranyl)phenyl]-5-cyclopropyl-1,2-oxazol-4-yl]methoxy]-2-chloranyl-phenyl]-3-oxidanyl-azetidin-1-yl]pyridine-4-carboxylic acid, Bile acid receptor, Peptide from Nuclear receptor coactivator 2 | Authors: | Jiang, L, Chen, Y.C. | Deposit date: | 2021-11-02 | Release date: | 2022-03-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Structural insight into the molecular mechanism of cilofexor binding to the farnesoid X receptor. Biochem.Biophys.Res.Commun., 595, 2022
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1DSW
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![BU of 1dsw by Molmil](/molmil-images/mine/1dsw) | THE SOLUTION STRUCTURE OF A MONOMERIC, REDUCED FORM OF HUMAN COPPER, ZINC SUPEROXIDE DISMUTASE BEARING THE SAME CHARGE AS THE NATIVE PROTEIN | Descriptor: | COPPER (II) ION, SUPEROXIDE DISMUTASE (CU-ZN), ZINC ION | Authors: | Banci, L, Bertini, I, Del Conte, R, Fadin, R, Mangani, S, Viezzoli, M.S. | Deposit date: | 2000-01-10 | Release date: | 2000-03-22 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | The solution structure of a monomeric, reduced form of human copper,zinc superoxide dismutase bearing the same charge as the native protein. J.Biol.Inorg.Chem., 4, 1999
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7VFB
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![BU of 7vfb by Molmil](/molmil-images/mine/7vfb) | the complex of SARS-CoV2 3cl and NB2B4 | Descriptor: | 3C-like proteinase, nb2b4 | Authors: | Geng, Y, Sun, Z.C, Wang, L. | Deposit date: | 2021-09-11 | Release date: | 2022-03-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | An extended conformation of SARS-CoV-2 main protease reveals allosteric targets. Proc.Natl.Acad.Sci.USA, 119, 2022
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1DXK
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![BU of 1dxk by Molmil](/molmil-images/mine/1dxk) | |
7V8G
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![BU of 7v8g by Molmil](/molmil-images/mine/7v8g) | Crystal structure of HOIP RING1 domain bound to IpaH1.4 LRR domain | Descriptor: | E3 ubiquitin-protein ligase RNF31, RING-type E3 ubiquitin transferase, ZINC ION | Authors: | Liu, J, Wang, Y, Pan, L. | Deposit date: | 2021-08-23 | Release date: | 2022-03-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri. Proc.Natl.Acad.Sci.USA, 119, 2022
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7V8E
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![BU of 7v8e by Molmil](/molmil-images/mine/7v8e) | Crystal structure of IpaH1.4 LRR domain bound to HOIL-1L UBL domain. | Descriptor: | RING-type E3 ubiquitin transferase, RanBP-type and C3HC4-type zinc finger-containing protein 1 | Authors: | Liu, J, Wang, Y, Pan, L. | Deposit date: | 2021-08-22 | Release date: | 2022-03-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri. Proc.Natl.Acad.Sci.USA, 119, 2022
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7V8F
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![BU of 7v8f by Molmil](/molmil-images/mine/7v8f) | Crystal structure of UBE2L3 bound to HOIP RING1 domain. | Descriptor: | E3 ubiquitin-protein ligase RNF31, Ubiquitin-conjugating enzyme E2 L3, ZINC ION | Authors: | Liu, J, Wang, Y, Pan, L. | Deposit date: | 2021-08-22 | Release date: | 2022-03-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri. Proc.Natl.Acad.Sci.USA, 119, 2022
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1E1G
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![BU of 1e1g by Molmil](/molmil-images/mine/1e1g) | Human prion protein variant M166V | Descriptor: | PRION PROTEIN | Authors: | Calzolai, L, Lysek, D.A, Guntert, P, Von Schroetter, C, Zahn, R, Riek, R, Wuthrich, K. | Deposit date: | 2000-05-04 | Release date: | 2000-07-20 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | NMR Structures of Three Single-Residue Variants of the Human Prion Protein Proc.Natl.Acad.Sci.USA, 97, 2000
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7VFA
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![BU of 7vfa by Molmil](/molmil-images/mine/7vfa) | the complex of SARS-CoV2 3CL and NB1A2 | Descriptor: | 3C-like proteinase, NB1A2, SULFATE ION | Authors: | Sun, Z.C, Wang, L, Geng, Y. | Deposit date: | 2021-09-11 | Release date: | 2022-03-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | An extended conformation of SARS-CoV-2 main protease reveals allosteric targets. Proc.Natl.Acad.Sci.USA, 119, 2022
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7VPN
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7V8H
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![BU of 7v8h by Molmil](/molmil-images/mine/7v8h) | Crystal structure of LRR domain from Shigella flexneri IpaH1.4 | Descriptor: | RING-type E3 ubiquitin transferase | Authors: | Liu, J, Wang, Y, Pan, L. | Deposit date: | 2021-08-23 | Release date: | 2022-03-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri. Proc.Natl.Acad.Sci.USA, 119, 2022
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1DOL
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![BU of 1dol by Molmil](/molmil-images/mine/1dol) | MONOCYTE CHEMOATTRACTANT PROTEIN 1, I-FORM | Descriptor: | MONOCYTE CHEMOATTRACTANT PROTEIN 1 | Authors: | Lubkowski, J, Bujacz, G, Boque, L, Wlodawer, A. | Deposit date: | 1996-11-22 | Release date: | 1997-03-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The structure of MCP-1 in two crystal forms provides a rare example of variable quaternary interactions. Nat.Struct.Biol., 4, 1997
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1DQ1
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![BU of 1dq1 by Molmil](/molmil-images/mine/1dq1) | Calcium;Calcium concanavalin A | Descriptor: | CALCIUM ION, Concanavalin-Br | Authors: | Bouckaert, J, Dewallef, Y, Poortmans, F, Wyns, L, Loris, R. | Deposit date: | 1999-12-29 | Release date: | 2000-01-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The structural features of concanavalin A governing non-proline peptide isomerization J.Biol.Chem., 275, 2000
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1DZQ
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![BU of 1dzq by Molmil](/molmil-images/mine/1dzq) | LECTIN UEA-II COMPLEXED WITH GALACTOSE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, LECTIN II, ... | Authors: | Loris, R, De Greve, H, Dao-Thi, M.-H, Messens, J, Imberty, A, Wyns, L. | Deposit date: | 2000-03-07 | Release date: | 2000-06-22 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural Basis of Carbohydrate Recognition by Lectin II from Ulex Europaeus, a Protein with a Promiscuous Carbohydrate Binding Site J.Mol.Biol., 301, 2000
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1E1U
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![BU of 1e1u by Molmil](/molmil-images/mine/1e1u) | Human prion protein variant R220K | Descriptor: | PRION PROTEIN | Authors: | Calzolai, L, Lysek, D.A, Guntert, P, Von Schroetter, C, Zahn, R, Riek, R, Wuthrich, K. | Deposit date: | 2000-05-11 | Release date: | 2000-07-20 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | NMR Structures of Three Single-Residue Variants of the Human Prion Protein Proc.Natl.Acad.Sci.USA, 97, 2000
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1DYP
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![BU of 1dyp by Molmil](/molmil-images/mine/1dyp) | 1,3-ALPHA-1,4-BETA-D-GALACTOSE-4-SULFATE-3,6-ANHYDRO-D-GALACTOSE 4 GALACTOHYDROLASE | Descriptor: | CADMIUM ION, CHLORIDE ION, KAPPA-CARRAGEENASE | Authors: | Michel, G, Chantalat, L, Dideberg, O. | Deposit date: | 2000-02-04 | Release date: | 2001-01-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | The Kappa-Carrageenase of P. Carrageenovora Features a Tunnel-Shaped Active Site: A Novel Insight in the Evolution of Clan-B Glycoside Hydrolases Structure, 9, 2001
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1E1P
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![BU of 1e1p by Molmil](/molmil-images/mine/1e1p) | Human prion protein variant S170N | Descriptor: | PRION PROTEIN | Authors: | Calzolai, L, Lysek, D.A, Guntert, P, Von Schroetter, C, Zahn, R, Riek, R, Wuthrich, K. | Deposit date: | 2000-05-09 | Release date: | 2000-07-20 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | NMR Structures of Three Single-Residue Variants of the Human Prion Protein Proc.Natl.Acad.Sci.USA, 97, 2000
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1DTH
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![BU of 1dth by Molmil](/molmil-images/mine/1dth) | METALLOPROTEASE | Descriptor: | 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, ATROLYSIN C, CALCIUM ION, ... | Authors: | Botos, I, Scapozza, L, Zhang, D, Liotta, L.A, Meyer, E.F. | Deposit date: | 1996-02-12 | Release date: | 1997-02-12 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Batimastat, a potent matrix mealloproteinase inhibitor, exhibits an unexpected mode of binding. Proc.Natl.Acad.Sci.USA, 93, 1996
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7FFT
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7FFW
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![BU of 7ffw by Molmil](/molmil-images/mine/7ffw) | The crystal structure of a domain-swapped dimeric maltodextrin-binding protein MalE from Salmonella enterica | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, METHOXYETHANE, ... | Authors: | Wang, L, Bu, T, Bai, X. | Deposit date: | 2021-07-23 | Release date: | 2021-09-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of the domain-swapped dimeric maltodextrin-binding protein MalE from Salmonella enterica. Acta Crystallogr D Struct Biol, 78, 2022
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1DO9
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![BU of 1do9 by Molmil](/molmil-images/mine/1do9) | SOLUTION STRUCTURE OF OXIDIZED MICROSOMAL RABBIT CYTOCHROME B5. FACTORS DETERMINING THE HETEROGENEOUS BINDING OF THE HEME. | Descriptor: | CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Banci, L, Bertini, I, Rosato, A, Scacchieri, S. | Deposit date: | 1999-12-20 | Release date: | 2000-01-05 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of oxidized microsomal rabbit cytochrome b5. Factors determining the heterogeneous binding of the heme. Eur.J.Biochem., 267, 2000
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1DT1
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![BU of 1dt1 by Molmil](/molmil-images/mine/1dt1) | THERMUS THERMOPHILUS CYTOCHROME C552 SYNTHESIZED BY ESCHERICHIA COLI | Descriptor: | CYTOCHROME C552, HEME C | Authors: | Fee, J.A, Chen, Y, Hill, M.J, Gomez-Moran, E, Loehr, T, Ai, J, Thony-Meyer, L, Williams, P.A, Stura, E, Sridhar, V, McRee, D.E. | Deposit date: | 2000-01-10 | Release date: | 2000-02-18 | Last modified: | 2021-03-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Integrity of thermus thermophilus cytochrome c552 synthesized by Escherichia coli cells expressing the host-specific cytochrome c maturation genes, ccmABCDEFGH: biochemical, spectral, and structural characterization of the recombinant protein. Protein Sci., 9, 2000
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1DZ5
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![BU of 1dz5 by Molmil](/molmil-images/mine/1dz5) | The NMR structure of the 38KDa U1A protein-PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein | Descriptor: | PIE, RNA (5'-R(*GP*AP*GP*AP*CP*AP*UP*UP*GP*CP*AP*CP*CP* CP*GP*GP*AP*GP*UP*CP*UP*C)-3'), U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A | Authors: | Varani, L, Gunderson, S.I, Mattaj, I.W, Kay, L.E, Neuhaus, D, Varani, G. | Deposit date: | 2000-02-16 | Release date: | 2000-03-29 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The NMR Structure of the 38kDa U1A Protein-Pie RNA Complex Reveals the Basis of Cooperativity in Regulation of Polyadenylation by Human U1A Protein Nat.Struct.Biol., 7, 2000
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1E1J
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![BU of 1e1j by Molmil](/molmil-images/mine/1e1j) | Human prion protein variant M166V | Descriptor: | PRION PROTEIN | Authors: | Calzolai, L, Lysek, D.A, Guntert, P, Von Schroetter, C, Zahn, R, Riek, R, Wuthrich, K. | Deposit date: | 2000-05-09 | Release date: | 2000-07-20 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | NMR Structures of Three Single-Residue Variants of the Human Prion Protein Proc.Natl.Acad.Sci.USA, 97, 2000
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1G37
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![BU of 1g37 by Molmil](/molmil-images/mine/1g37) | CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN COMPLEXED WITH BCH-10556 AND EXOSITE-DIRECTED PEPTIDE | Descriptor: | 3-(4-AMINO-CYCLOHEXYL)-2-HYDROXY-3-[(4-OXO-2-PHENYLMETHANESULFONYL-1,2,3,4-TETRAHYDRO-PYRROLO[1,2-A]PYRAZINE-6-CARBONYL)-AMINO]-PROPIONIC ACID BUTYL ESTER, ALPHA THROMBIN, THROMBIN NONAPEPTIDE INHIBITOR | Authors: | Bachand, B, Tarazi, M, St-Denis, Y, Edmunds, J.J, Winocour, P.D, Leblond, L, Siddiqui, M.A. | Deposit date: | 2000-10-23 | Release date: | 2001-04-21 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Potent and selective bicyclic lactam inhibitors of thrombin. Part 4: transition state inhibitors. Bioorg.Med.Chem.Lett., 11, 2001
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