7VPN

Crystal Structure of the dioxygenase CcTet from Coprinopsis cinereain in complex with Mn(II) and N-Oxalylglycine

Summary for 7VPN

Entry DOI	10.2210/pdb7vpn/pdb
Descriptor	CcTet molecule, MANGANESE (II) ION, N-OXALYLGLYCINE, ... (4 entities in total)
Functional Keywords	dioxygenase, 5-methylcytosine oxidation, n6-methyldeoxyadenine demethylation, dna binding protein
Biological source	Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003) (Inky cap fungus, Hormographiella aspergillata)
Total number of polymer chains	4
Total formula weight	192838.75
Authors	Mu, Y.J.,Zhang, L.,Zhang, L. (deposition date: 2021-10-17, release date: 2022-03-30, Last modification date: 2023-11-29)
Primary citation	Mu, Y.,Zhang, L.,Hu, J.,Zhou, J.,Lin, H.W.,He, C.,Chen, H.Z.,Zhang, L. A fungal dioxygenase CcTet serves as a eukaryotic 6mA demethylase on duplex DNA. Nat.Chem.Biol., 18:733-741, 2022 Cited by PubMed: 35654845 DOI: 10.1038/s41589-022-01041-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation