8HAE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hae by Molmil](/molmil-images/mine/8hae) | Cryo-EM structure of HACE1 dimer | Descriptor: | E3 ubiquitin-protein ligase HACE1 | Authors: | Singh, S, Machida, S, Tulsian, N.K, Choong, Y.K, Ng, J, Shanker, S, Yaochen, L.D, Shi, J, Sivaraman, J, Machida, S. | Deposit date: | 2022-10-26 | Release date: | 2023-06-28 | Last modified: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (4.55 Å) | Cite: | Structural Basis for the Enzymatic Activity of the HACE1 HECT-Type E3 Ligase Through N-Terminal Helix Dimerization. Adv Sci, 10, 2023
|
|
8H8X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8h8x by Molmil](/molmil-images/mine/8h8x) | Cryo-EM structure of HACE1 monomer | Descriptor: | E3 ubiquitin-protein ligase HACE1 | Authors: | Singh, S, Machida, S, Tulsian, N.K, Choong, Y.K, Ng, J, Shanker, S, Yaochen, L.D, Shi, J, Sivaraman, J. | Deposit date: | 2022-10-24 | Release date: | 2023-06-28 | Last modified: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (3.92 Å) | Cite: | Structural Basis for the Enzymatic Activity of the HACE1 HECT-Type E3 Ligase Through N-Terminal Helix Dimerization. Adv Sci, 10, 2023
|
|
7WF3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wf3 by Molmil](/molmil-images/mine/7wf3) | Composite map of human Kv1.3 channel in apo state with beta subunits | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3, ... | Authors: | Tyagi, A, Ahmed, T, Jian, S, Bajaj, S, Ong, S.T, Goay, S.S.M, Zhao, Y, Vorobyov, I, Tian, C, Chandy, K.G, Bhushan, S. | Deposit date: | 2021-12-25 | Release date: | 2022-02-09 | Last modified: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7WF4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wf4 by Molmil](/molmil-images/mine/7wf4) | Composite map of human Kv1.3 channel in dalazatide-bound state with beta subunits | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3, ... | Authors: | Tyagi, A, Ahmed, T, Jian, S, Bajaj, S, Ong, S.T, Goay, S.S.M, Zhao, Y, Vorobyov, I, Tian, C, Chandy, K.G, Bhushan, S. | Deposit date: | 2021-12-25 | Release date: | 2022-02-09 | Last modified: | 2022-05-25 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7OYY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7oyy by Molmil](/molmil-images/mine/7oyy) | E.coli's putrescine receptor variant PotF/D (4JDF) with mutation S247D in complex with spermidine | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Kroeger, P, Shanmugaratnam, S, Hocker, B. | Deposit date: | 2021-06-25 | Release date: | 2021-12-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Fine-tuning spermidine binding modes in the putrescine binding protein PotF. J.Biol.Chem., 297, 2021
|
|
7SN3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sn3 by Molmil](/molmil-images/mine/7sn3) | Structure of human SARS-CoV-2 spike glycoprotein trimer bound by neutralizing antibody C1C-A3 Fab (variable region) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Pan, J, Abraham, J, Shankar, S. | Deposit date: | 2021-10-27 | Release date: | 2021-12-08 | Last modified: | 2022-02-02 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain. Science, 375, 2022
|
|
7SN2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sn2 by Molmil](/molmil-images/mine/7sn2) | Structure of human SARS-CoV-2 neutralizing antibody C1C-A3 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Pan, J, Abraham, J, Yang, P, Shankar, S. | Deposit date: | 2021-10-27 | Release date: | 2021-12-08 | Last modified: | 2022-02-02 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain. Science, 375, 2022
|
|
2WWB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wwb by Molmil](/molmil-images/mine/2wwb) | CRYO-EM STRUCTURE OF THE MAMMALIAN SEC61 COMPLEX BOUND TO THE ACTIVELY TRANSLATING WHEAT GERM 80S RIBOSOME | Descriptor: | 25S RRNA, 5.8S RRNA, 60S RIBOSOMAL PROTEIN L17-A, ... | Authors: | Becker, T, Mandon, E, Bhushan, S, Jarasch, A, Armache, J.P, Funes, S, Jossinet, F, Gumbart, J, Mielke, T, Berninghausen, O, Schulten, K, Westhof, E, Gilmore, R, Beckmann, R. | Deposit date: | 2009-10-22 | Release date: | 2009-12-08 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6.48 Å) | Cite: | Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome. Science, 326, 2009
|
|
2WW9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ww9 by Molmil](/molmil-images/mine/2ww9) | Cryo-EM structure of the active yeast Ssh1 complex bound to the yeast 80S ribosome | Descriptor: | 25S RRNA, 60S RIBOSOMAL PROTEIN L17-A, 60S RIBOSOMAL PROTEIN L19, ... | Authors: | Becker, T, Mandon, E, Bhushan, S, Jarasch, A, Armache, J.P, Funes, S, Jossinet, F, Gumbart, J, Mielke, T, Berninghausen, O, Schulten, K, Westhof, E, Gilmore, R, Beckmann, R. | Deposit date: | 2009-10-22 | Release date: | 2009-12-08 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.6 Å) | Cite: | Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome. Science, 326, 2009
|
|
2WWA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wwa by Molmil](/molmil-images/mine/2wwa) | Cryo-EM structure of idle yeast Ssh1 complex bound to the yeast 80S ribosome | Descriptor: | 25S RRNA, 60S RIBOSOMAL PROTEIN L17-A, 60S RIBOSOMAL PROTEIN L19, ... | Authors: | Becker, T, Mandon, E, Bhushan, S, Jarasch, A, Armache, J.P, Funes, S, Jossinet, F, Gumbart, J, Mielke, T, Berninghausen, O, Schulten, K, Westhof, E, Gilmore, R, Beckmann, R. | Deposit date: | 2009-10-22 | Release date: | 2009-12-08 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.9 Å) | Cite: | Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome. Science, 326, 2009
|
|
8AT0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8at0 by Molmil](/molmil-images/mine/8at0) | PotF with mutation D247K | Descriptor: | (2R)-1-methoxypropan-2-amine, (2~{S})-1-(2-methoxyethoxy)propan-2-amine, 1,2-ETHANEDIOL, ... | Authors: | Kroeger, P, Shanmugaratnam, S, Hocker, B. | Deposit date: | 2022-08-22 | Release date: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A fluorescent biosensor for the visualization of Agmatine To Be Published
|
|
8ASZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8asz by Molmil](/molmil-images/mine/8asz) | |
8R8O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8r8o by Molmil](/molmil-images/mine/8r8o) | Hallucinated de novo TIM barrel with three helical extensions - HalluTIM3-1 | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Beck, J, Shanmugaratnam, S, Hocker, B. | Deposit date: | 2023-11-29 | Release date: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Diversifying de novo TIM barrels by hallucination. Protein Sci., 33, 2024
|
|
8R8N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8r8n by Molmil](/molmil-images/mine/8r8n) | |
1T61
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1t61 by Molmil](/molmil-images/mine/1t61) | crystal structure of collagen IV NC1 domain from placenta basement membrane | Descriptor: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Vanacore, R.M, Shanmugasundararaj, S, Friedman, D.B, Bondar, O, Hudson, B.G, Sundaramoorthy, M. | Deposit date: | 2004-05-05 | Release date: | 2004-09-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The alpha1.alpha2 network of collagen IV. Reinforced stabilization of the noncollagenous domain-1 by noncovalent forces and the absence of Met-Lys cross-links J.Biol.Chem., 279, 2004
|
|
7LUP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lup by Molmil](/molmil-images/mine/7lup) | Human TRiC/CCT complex with reovirus outer capsid protein sigma-3 | Descriptor: | Outer capsid protein sigma-3, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ... | Authors: | Knowlton, J.J, Gestaut, D, Ma, B, Taylor, G, Seven, A.B, Leitner, A, Wilson, G.J, Shanker, S, Yates, N.A, Prasad, B.V.V, Aebersold, R, Chiu, W, Frydman, J, Dermody, T.S. | Deposit date: | 2021-02-22 | Release date: | 2021-03-03 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | Structural and functional dissection of reovirus capsid folding and assembly by the prefoldin-TRiC/CCT chaperone network. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7LUM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lum by Molmil](/molmil-images/mine/7lum) | Human TRiC in ATP/AlFx closed state | Descriptor: | T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ... | Authors: | Knowlton, J.J, Gestaut, D, Ma, B, Taylor, G, Seven, A.B, Leitner, A, Wilson, G.J, Shanker, S, Yates, N.A, Prasad, B.V.V, Aebersold, R, Chiu, W, Frydman, J, Dermody, T.S. | Deposit date: | 2021-02-22 | Release date: | 2021-03-03 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural and functional dissection of reovirus capsid folding and assembly by the prefoldin-TRiC/CCT chaperone network. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
6QGM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qgm by Molmil](/molmil-images/mine/6qgm) | VirX1 apo structure | Descriptor: | VirX1 | Authors: | Gkotsi, D.S, Ludewig, H, Sharma, S.V, Unsworth, W.P, Taylor, R.J.K, McLachlan, M.M.W, Shanahan, S, Naismith, J.H, Goss, R.J.M. | Deposit date: | 2019-01-11 | Release date: | 2019-10-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | A marine viral halogenase that iodinates diverse substrates. Nat.Chem., 11, 2019
|
|
5ZEU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zeu by Molmil](/molmil-images/mine/5zeu) | M. smegmatis P/P state 30S ribosomal subunit | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Mishra, S, Ahmed, T, Tyagi, A, Shi, J, Bhushan, S. | Deposit date: | 2018-02-28 | Release date: | 2018-09-26 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structures of Mycobacterium smegmatis 70S ribosomes in complex with HPF, tmRNA, and P-tRNA. Sci Rep, 8, 2018
|
|
5ZEY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zey by Molmil](/molmil-images/mine/5zey) | M. smegmatis Trans-translation state 70S ribosome | Descriptor: | A-tRNAfMet, SsrA-binding protein, tmRNA | Authors: | Mishra, S, Ahmed, T, Tyagi, A, Shi, J, Bhushan, S. | Deposit date: | 2018-02-28 | Release date: | 2018-09-26 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (12.5 Å) | Cite: | Structures of Mycobacterium smegmatis 70S ribosomes in complex with HPF, tmRNA, and P-tRNA. Sci Rep, 8, 2018
|
|
5ZEB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zeb by Molmil](/molmil-images/mine/5zeb) | M. Smegmatis P/P state 70S ribosome structure | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Mishra, S, Ahmed, T, Tyagi, A, Shi, J, Bhushan, S. | Deposit date: | 2018-02-27 | Release date: | 2018-09-26 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of Mycobacterium smegmatis 70S ribosomes in complex with HPF, tmRNA, and P-tRNA. Sci Rep, 8, 2018
|
|
5ZET
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zet by Molmil](/molmil-images/mine/5zet) | M. smegmatis P/P state 50S ribosomal subunit | Descriptor: | 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | Authors: | Mishra, S, Ahmed, T, Tyagi, A, Shi, J, Bhushan, S. | Deposit date: | 2018-02-28 | Release date: | 2018-09-26 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures of Mycobacterium smegmatis 70S ribosomes in complex with HPF, tmRNA, and P-tRNA. Sci Rep, 8, 2018
|
|
6SLD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6sld by Molmil](/molmil-images/mine/6sld) | Structure of the Phosphatidylcholine Binding Mutant of Yeast Sec14 Homolog Sfh1 (S175I,T177I) in Complex with Phosphatidylinositol | Descriptor: | (1R)-2-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CRAL-TRIO domain-containing protein YKL091C | Authors: | Berger, J, Fitz, M, Johnen, P, Shanmugaratnam, S, Hocker, B, Stiel, A.C, Schaaf, G. | Deposit date: | 2019-08-19 | Release date: | 2020-08-19 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure of the Phosphatidylcholine Binding Mutant of Yeast Sec14 Homolog Sfh1 (S175I,T177I) in Complex with Phosphatidylinositol To Be Published
|
|
5ZEP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zep by Molmil](/molmil-images/mine/5zep) | M. smegmatis hibernating state 70S ribosome structure | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Mishra, S, Ahmed, T, Tyagi, A, Shi, J, Bhushan, S. | Deposit date: | 2018-02-27 | Release date: | 2018-09-26 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of Mycobacterium smegmatis 70S ribosomes in complex with HPF, tmRNA, and P-tRNA. Sci Rep, 8, 2018
|
|
5H1S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h1s by Molmil](/molmil-images/mine/5h1s) | Structure of the large subunit of the chloro-ribosome | Descriptor: | 23S rRNA, 50S ribosomal protein L15, 50S ribosomal protein L17, ... | Authors: | Ahmed, T, Yin, Z, Bhushan, S. | Deposit date: | 2016-10-11 | Release date: | 2017-02-01 | Last modified: | 2018-06-06 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structure of the large subunit of the spinach chloroplast ribosome. Sci Rep, 6, 2016
|
|