1H03
 
 | | Human CD55 domains 3 & 4 | | Descriptor: | COMPLEMENT DECAY-ACCELERATING FACTOR | | Authors: | Williams, P, Chaudhry, Y, Goodfellow, I, Billington, J, Spiller, B, Evans, D.J, Lea, S.M. | | Deposit date: | 2002-06-11 | | Release date: | 2003-03-20 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A
J.Biol.Chem., 278, 2003
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1H2P
 | | Human CD55 domains 3 & 4 | | Descriptor: | COMPLEMENT DECAY-ACCELERATING FACTOR | | Authors: | Williams, P, Chaudhry, Y, Goodfellow, I, Billington, J, Spiller, B, Evans, D.J, Lea, S.M. | | Deposit date: | 2002-08-13 | | Release date: | 2003-03-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A
J.Biol.Chem., 278, 2003
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5LHX
 | | PB3 Domain of Drosophila melanogaster PLK4 (Sak) | | Descriptor: | Serine/threonine-protein kinase PLK4 | | Authors: | Cottee, M.A, Lea, S.M. | | Deposit date: | 2016-07-13 | | Release date: | 2017-03-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies.
Biol Open, 6, 2017
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5LHY
 | | PB3 Domain of Human PLK4 (apo) | | Descriptor: | Serine/threonine-protein kinase PLK4 | | Authors: | Cottee, M.A, Johnson, S, Lea, S.M. | | Deposit date: | 2016-07-13 | | Release date: | 2017-03-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.31 Å) | | Cite: | A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies.
Biol Open, 6, 2017
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5LHZ
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5MWE
 | | Complex between the Leucine Zipper (LZ, residues 490-567) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) | | Descriptor: | 1,2-ETHANEDIOL, 3,3',3''-phosphanetriyltripropanoic acid, Centrosomin, ... | | Authors: | Feng, Z, Johnson, S, Raff, J.W, Lea, S.M. | | Deposit date: | 2017-01-18 | | Release date: | 2017-06-28 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | Structural Basis for Mitotic Centrosome Assembly in Flies.
Cell, 169, 2017
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5MW9
 | | Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) - L535E mutant form | | Descriptor: | Centrosomin, ZINC ION | | Authors: | Feng, Z, Johnson, S, Raff, J.W, Lea, S.M. | | Deposit date: | 2017-01-18 | | Release date: | 2017-06-28 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural Basis for Mitotic Centrosome Assembly in Flies.
Cell, 169, 2017
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5MVW
 | | Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Centrosomin, ... | | Authors: | Feng, Z, Johnson, S, Raff, J.W, Lea, S.M. | | Deposit date: | 2017-01-17 | | Release date: | 2017-06-28 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Structural Basis for Mitotic Centrosome Assembly in Flies.
Cell, 169, 2017
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5MW0
 | | Complex between the Leucine Zipper (LZ) and Centrosomin-motif 2 (CM2) domains of Drosophila melanogaster Centrosomin (Cnn) - L535E mutant form | | Descriptor: | Centrosomin, ZINC ION | | Authors: | Feng, Z, Johnson, S, Raff, J.W, Lea, S.M. | | Deposit date: | 2017-01-17 | | Release date: | 2017-06-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Basis for Mitotic Centrosome Assembly in Flies.
Cell, 169, 2017
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5MVX
 | | Human DLL4 C2-EGF3 | | Descriptor: | Delta-like protein 4, alpha-L-fucopyranose | | Authors: | Suckling, R.J, Handford, P.A, Lea, S.M. | | Deposit date: | 2017-01-17 | | Release date: | 2017-06-14 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.
EMBO J., 36, 2017
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5MW7
 | | Human Jagged2 C2-EGF3 | | Descriptor: | Protein jagged-2, alpha-L-fucopyranose | | Authors: | Suckling, R.J, Handford, P.A, Lea, S.M. | | Deposit date: | 2017-01-18 | | Release date: | 2017-06-14 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.
EMBO J., 36, 2017
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5MWB
 | | Human Notch-2 EGF11-13 | | Descriptor: | CALCIUM ION, Neurogenic locus notch homolog protein 2, alpha-L-fucopyranose, ... | | Authors: | Suckling, R.J, Handford, P.A, Lea, S.M. | | Deposit date: | 2017-01-18 | | Release date: | 2017-06-14 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.
EMBO J., 36, 2017
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5MW5
 | | Human Jagged2 C2-EGF2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Protein jagged-2 | | Authors: | Suckling, R.J, Handford, P.A, Lea, S.M. | | Deposit date: | 2017-01-18 | | Release date: | 2017-06-14 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.
EMBO J., 36, 2017
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5MWF
 | | Human Jagged2 C2-EGF2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | | Authors: | Suckling, R.J, Handford, P.A, Lea, S.M. | | Deposit date: | 2017-01-18 | | Release date: | 2017-06-14 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.
EMBO J., 36, 2017
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5NQY
 | | Structure of a fHbp(V1.4):PorA(P1.16) chimera. Fusion at fHbp position 309. | | Descriptor: | Factor H binding protein variant B16_001,Major outer membrane protein P.IA,Factor H binding protein variant B16_001 | | Authors: | Johnson, S, Hollingshead, S, Lea, S.M, Tang, C.M. | | Deposit date: | 2017-04-21 | | Release date: | 2018-02-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure-based design of chimeric antigens for multivalent protein vaccines.
Nat Commun, 9, 2018
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5NQZ
 | | Structure of a fHbp(V1.1):PorA(P1.16) chimera. Fusion at fHbp position 309. | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Factor H binding protein,Major outer membrane protein P.IA,Factor H binding protein, ... | | Authors: | Johnson, S, Hollingshead, S, Lea, S.M, Tang, C.M. | | Deposit date: | 2017-04-21 | | Release date: | 2018-02-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Structure-based design of chimeric antigens for multivalent protein vaccines.
Nat Commun, 9, 2018
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5LHW
 | | Central Coiled-Coil Domain of Human STIL | | Descriptor: | HEXAETHYLENE GLYCOL, SCL-interrupting locus protein | | Authors: | Cottee, M.A, Lea, S.M. | | Deposit date: | 2016-07-13 | | Release date: | 2017-03-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (0.91 Å) | | Cite: | A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies.
Biol Open, 6, 2017
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5NQX
 | | Structure of a fHbp(V1.1):PorA(P1.16) chimera. Fusion at fHbp position 294. | | Descriptor: | Factor H binding protein,Major outer membrane protein P.IA,Factor H binding protein | | Authors: | Johnson, S, Jongerius, I, Lea, S.M, Tang, C.M. | | Deposit date: | 2017-04-21 | | Release date: | 2018-02-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.66 Å) | | Cite: | Structure-based design of chimeric antigens for multivalent protein vaccines.
Nat Commun, 9, 2018
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5NQP
 | | Structure of a fHbp(V1.4):PorA(P1.16) chimera. Fusion at fHbp position 151. | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Factor H binding protein variant B16_001,Major outer membrane protein P.IA,Factor H binding protein variant B16_001, ... | | Authors: | Johnson, S, Hollingshead, S, Lea, S.M, Tang, C.M. | | Deposit date: | 2017-04-20 | | Release date: | 2018-02-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.86 Å) | | Cite: | Structure-based design of chimeric antigens for multivalent protein vaccines.
Nat Commun, 9, 2018
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4TT9
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1H2Q
 | | Human CD55 domains 3 & 4 | | Descriptor: | COMPLEMENT DECAY-ACCELERATING FACTOR | | Authors: | Williams, P, Chaudhry, Y, Goodfellow, I.G, Billington, J, Powell, R, Spiller, O.B, Evans, D.J, Lea, S.M. | | Deposit date: | 2002-08-13 | | Release date: | 2003-09-25 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Mapping Cd55 Function. The Structure of Two Pathogen-Binding Domains at 1.7 A
J.Biol.Chem., 278, 2003
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2J0N
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2IXR
 | | BipD of Burkholderia Pseudomallei | | Descriptor: | MEMBRANE ANTIGEN | | Authors: | Roversi, P, Johnson, S, Field, T, Deane, J.E, Galyov, E.E, Lea, S.M. | | Deposit date: | 2006-07-10 | | Release date: | 2006-11-02 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Self-Chaperoning of the Type III Secretion System Needle Tip Proteins Ipad and Bipd.
J.Biol.Chem., 282, 2007
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2J0O
 | | Shigella Flexneri IpaD | | Descriptor: | GLYCEROL, INVASIN IPAD | | Authors: | Johnson, S, Roversi, P, Lea, S.M. | | Deposit date: | 2006-08-04 | | Release date: | 2006-11-02 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Self-chaperoning of the type III secretion system needle tip proteins IpaD and BipD.
J. Biol. Chem., 282, 2007
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2J9T
 | | BipD of Burkholderia Pseudomallei | | Descriptor: | BORIC ACID, CITRATE ANION, MEMBRANE ANTIGEN | | Authors: | Johnson, S, Roversi, P, Field, T, Deane, J.E, Galyov, E, Lea, S.M. | | Deposit date: | 2006-11-16 | | Release date: | 2006-11-20 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Self-Chaperoning of the Type III Secretion System Needle Tip Proteins Ipad and Bipd.
J.Biol.Chem., 282, 2007
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