5LHZ
PB3 Domain of Human PLK4 in Complex with Coiled-Coil Domain of STIL
Summary for 5LHZ
| Entry DOI | 10.2210/pdb5lhz/pdb |
| Descriptor | Serine/threonine-protein kinase PLK4, SCL-interrupting locus protein (3 entities in total) |
| Functional Keywords | polo box domain, centriole, complex, transferase, structural protein |
| Biological source | Homo sapiens (Human) More |
| Cellular location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole : O00444 Cytoplasm, cytosol : Q15468 |
| Total number of polymer chains | 6 |
| Total formula weight | 39344.56 |
| Authors | Cottee, M.A.,Lea, S.M. (deposition date: 2016-07-13, release date: 2017-03-01, Last modification date: 2024-01-10) |
| Primary citation | Cottee, M.A.,Johnson, S.,Raff, J.W.,Lea, S.M. A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies. Biol Open, 6:381-389, 2017 Cited by PubMed: 28202467DOI: 10.1242/bio.024661 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.51 Å) |
Structure validation
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