7XMZ
 
 | | Cryo-EM structure of SARS-CoV-2 spike glycoprotein in complex with three D2 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D2 heavy chain, D2 light chain, ... | | Authors: | Wang, X, Li, X. | | Deposit date: | 2022-04-27 | | Release date: | 2022-11-23 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages.
Cell Discov, 8, 2022
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7XMX
 | | Cryo-EM structure of SARS-CoV-2 spike glycoprotein in complex with three F61 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F61 heavy chain, F61 light chain, ... | | Authors: | Wang, X, Li, X. | | Deposit date: | 2022-04-27 | | Release date: | 2022-11-23 | | Method: | ELECTRON MICROSCOPY (3.62 Å) | | Cite: | Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages.
Cell Discov, 8, 2022
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7E58
 | | interferon-inducible anti-viral protein 2 | | Descriptor: | Guanylate-binding protein 2 | | Authors: | Cui, W, Wang, W, Chen, C, Slater, B, Xiong, Y, Ji, X.Y, Yang, H.T. | | Deposit date: | 2021-02-18 | | Release date: | 2021-05-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7E59
 | | interferon-inducible anti-viral protein truncated | | Descriptor: | Guanylate-binding protein 5 | | Authors: | Cui, W, Wang, W, Chen, C, Slater, B, Xiong, Y, Ji, X.Y, Yang, H.T. | | Deposit date: | 2021-02-18 | | Release date: | 2021-05-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7E5A
 | | interferon-inducible anti-viral protein R356A | | Descriptor: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, Guanylate-binding protein 5, ... | | Authors: | Cui, W, Wang, W, Chen, C, Slater, B, Xiong, Y, Ji, X.Y, Yang, H.T. | | Deposit date: | 2021-02-18 | | Release date: | 2021-05-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
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5WLY
 | | E. coli LpxH- 8 mutations | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, FORMIC ACID, ... | | Authors: | Bohl, T.E, Aihara, H, Shi, K, Lee, J.K. | | Deposit date: | 2017-07-28 | | Release date: | 2018-04-11 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The substrate-binding cap of the UDP-diacylglucosamine pyrophosphatase LpxH is highly flexible, enabling facile substrate binding and product release.
J. Biol. Chem., 293, 2018
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5W2L
 | | Structure of a central domain of human Ctc1 | | Descriptor: | CST complex subunit CTC1, MERCURY (II) ION | | Authors: | Rice, C, Skordalakes, E. | | Deposit date: | 2017-06-06 | | Release date: | 2017-11-29 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Structural and functional analysis of an OB-fold in human Ctc1 implicated in telomere maintenance and bone marrow syndromes.
Nucleic Acids Res., 46, 2018
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5W2O
 | | Crystal structure of Mycobacterium tuberculosis KasA | | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 1, CHLORIDE ION, ... | | Authors: | Capodagli, G.C, Neiditch, M.B. | | Deposit date: | 2017-06-06 | | Release date: | 2018-12-05 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Synergistic Lethality of a Binary Inhibitor of Mycobacterium tuberculosis KasA.
MBio, 9, 2018
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7XST
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7BY7
 | | Bacteriophage SPO1 protein Gp46 | | Descriptor: | Putative gene 46 protein | | Authors: | Liu, B, Zhang, P. | | Deposit date: | 2020-04-22 | | Release date: | 2021-04-28 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Bacteriophage protein Gp46 is a cross-species inhibitor of nucleoid-associated HU proteins
Proc.Natl.Acad.Sci.USA, 119, 2022
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7CKF
 | | The N-terminus of interferon-inducible antiviral protein-dimer | | Descriptor: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, Guanylate-binding protein 5, ... | | Authors: | Cui, W, Yang, H.T. | | Deposit date: | 2020-07-16 | | Release date: | 2021-05-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.284 Å) | | Cite: | Structural basis for GTP-induced dimerization and antiviral function of guanylate-binding proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
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4JAJ
 | | Crystal Structure of Aurora Kinase A in complex with BENZO[C][1,8]NAPHTHYRIDIN-6(5H)-ONE | | Descriptor: | Aurora kinase A, benzo[c][1,8]naphthyridin-6(5H)-one | | Authors: | Jiang, X, Josephson, K, Huck, B, Goutopoulos, A, Karra, S. | | Deposit date: | 2013-02-18 | | Release date: | 2013-05-22 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | SAR and evaluation of novel 5H-benzo[c][1,8]naphthyridin-6-one analogs as Aurora kinase inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
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7DMO
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7DMN
 | | Crystal structure of two pericyclases catalyzing [4+2] cycloaddition | | Descriptor: | Diels-Alderase fsa2, GLYCEROL | | Authors: | Chi, C.B, Wang, Z.D, Liu, T, Zhang, Z.Y, Ma, M. | | Deposit date: | 2020-12-04 | | Release date: | 2021-10-06 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structures of Fsa2 and Phm7 Catalyzing [4 + 2] Cycloaddition Reactions with Reverse Stereoselectivities in Equisetin and Phomasetin Biosynthesis.
Acs Omega, 6, 2021
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7WH8
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4JAI
 | | Crystal Structure of Aurora Kinase A in complex with N-{4-[(6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridin-1-yl)amino]phenyl}benzamide | | Descriptor: | Aurora kinase A, N-{4-[(6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridin-1-yl)amino]phenyl}benzamide | | Authors: | Jiang, X, Josephson, K, Huck, B, Goutopoulos, A, Karra, S. | | Deposit date: | 2013-02-18 | | Release date: | 2013-05-22 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | SAR and evaluation of novel 5H-benzo[c][1,8]naphthyridin-6-one analogs as Aurora kinase inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
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4L8C
 | | Crystal structure of the H2Db in complex with the NP-N3D peptide | | Descriptor: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | | Authors: | Rossjohn, J, Gras, S. | | Deposit date: | 2013-06-16 | | Release date: | 2013-10-16 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Acute emergence and reversion of influenza A virus quasispecies within CD8(+) T cell antigenic peptides.
Nat Commun, 4, 2013
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4L8B
 | | Crystal structure of the H2Db in complex with the NP-N5H peptide | | Descriptor: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, H-2 class I histocompatibility antigen, ... | | Authors: | Rossjohn, J, Gras, S. | | Deposit date: | 2013-06-16 | | Release date: | 2013-10-16 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Acute emergence and reversion of influenza A virus quasispecies within CD8(+) T cell antigenic peptides.
Nat Commun, 4, 2013
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4L8D
 | | Crystal structure of the H2Db in complex with the NP-N5D peptide | | Descriptor: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | | Authors: | Rossjohn, J, Gras, S. | | Deposit date: | 2013-06-16 | | Release date: | 2013-10-16 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Acute emergence and reversion of influenza A virus quasispecies within CD8(+) T cell antigenic peptides.
Nat Commun, 4, 2013
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3SUZ
 | | Crystal structure of Rat Mint2 PPC | | Descriptor: | Amyloid beta A4 precursor protein-binding family A member 2 | | Authors: | Shen, Y, Long, J, Yan, X, Xie, X. | | Deposit date: | 2011-07-11 | | Release date: | 2012-07-11 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Open-closed motion of Mint2 regulates APP metabolism
J Mol Cell Biol, 5, 2013
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6IWV
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4M6T
 | | Structure of human Paf1 and Leo1 complex | | Descriptor: | RNA polymerase II-associated factor 1 homolog, Linker, RNA polymerase-associated protein LEO1, ... | | Authors: | Shen, Y, Qin, X. | | Deposit date: | 2013-08-11 | | Release date: | 2013-10-02 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.498 Å) | | Cite: | Structural insights into Paf1 complex assembly and histone binding
Nucleic Acids Res., 41, 2013
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3UIT
 | | Overall structure of Patj/Pals1/Mals complex | | Descriptor: | ACETATE ION, InaD-like protein, MAGUK p55 subfamily member 5, ... | | Authors: | Zhang, J, Yang, X, Long, J, Shen, Y. | | Deposit date: | 2011-11-06 | | Release date: | 2012-02-22 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structure of an L27 domain heterotrimer from cell polarity complex Patj/Pals1/Mals2 reveals mutually independent L27 domain assembly mode
J.Biol.Chem., 287, 2012
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3SOW
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3RY2
 | | Wild-type core streptavidin-biotin complex at atomic resolution | | Descriptor: | BIOTIN, GLYCEROL, Streptavidin | | Authors: | Stenkamp, R.E, Le Trong, I, Stayton, P.S, Lybrand, T.P. | | Deposit date: | 2011-05-10 | | Release date: | 2011-08-24 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (0.95 Å) | | Cite: | Streptavidin and its biotin complex at atomic resolution.
Acta Crystallogr.,Sect.D, 67, 2011
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