7WH8

SARS-CoV-2 spike in complex with the ZB8 neutralizing antibody Fab (focused refinement on Fab-RBD)

Summary for 7WH8

• Entry DOI: 10.2210/pdb7wh8/pdb
• EMDB information: 32497
• Descriptor: antibody ZB8 heavy chain, antibody ZB8 light chain, Spike glycoprotein (3 entities in total)
• Functional Keywords: sars-cov-2 spike, receptor binding domain, antibody, viral protein, immune system-viral protein complex, immune system/viral protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 77872.21

Authors

Zeng, J.W. (deposition date: 2021-12-30, release date: 2023-01-18, Last modification date: 2023-09-06)

• Primary citation: Zhou, B.,Zhou, R.,Chan, J.F.,Zeng, J.,Zhang, Q.,Yuan, S.,Liu, L.,Robinot, R.,Shan, S.,Liu, N.,Ge, J.,Kwong, H.Y.,Zhou, D.,Xu, H.,Chan, C.C.,Poon, V.K.,Chu, H.,Yue, M.,Kwan, K.Y.,Chan, C.Y.,Chan, C.C.,Chik, K.K.,Du, Z.,Au, K.K.,Huang, H.,Man, H.O.,Cao, J.,Li, C.,Wang, Z.,Zhou, J.,Song, Y.,Yeung, M.L.,To, K.K.,Ho, D.D.,Chakrabarti, L.A.,Wang, X.,Zhang, L.,Yuen, K.Y.,Chen, Z.; SARS-CoV-2 hijacks neutralizing dimeric IgA for nasal infection and injury in Syrian hamsters 1 .; Emerg Microbes Infect, 12:2245921-2245921, 2023; PubMed: 37542391; DOI: 10.1080/22221751.2023.2245921

Experimental method

ELECTRON MICROSCOPY (3.11 Å)