4D9P
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![BU of 4d9p by Molmil](/molmil-images/mine/4d9p) | Crystal structure of B. anthracis DHPS with compound 17 | Descriptor: | (3R)-3-(7-amino-1-methyl-4,5-dioxo-1,4,5,6-tetrahydropyrimido[4,5-c]pyridazin-3-yl)butanoic acid, Dihydropteroate Synthase, SULFATE ION | Authors: | Hammoudeh, D, Lee, R.E, White, S.W. | Deposit date: | 2012-01-11 | Release date: | 2012-03-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Structure-Based Design of Novel Pyrimido[4,5-c]pyridazine Derivatives as Dihydropteroate Synthase Inhibitors with Increased Affinity. Chemmedchem, 7, 2012
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4D8A
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![BU of 4d8a by Molmil](/molmil-images/mine/4d8a) | Crystal structure of B. anthracis DHPS with compound 21 | Descriptor: | Dihydropteroate synthase, LYSINE, SULFATE ION, ... | Authors: | Hammoudeh, D, Lee, R.E, White, S.W. | Deposit date: | 2012-01-10 | Release date: | 2012-04-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.183 Å) | Cite: | Structure-Based Design of Novel Pyrimido[4,5-c]pyridazine Derivatives as Dihydropteroate Synthase Inhibitors with Increased Affinity. Chemmedchem, 7, 2012
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4DAF
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![BU of 4daf by Molmil](/molmil-images/mine/4daf) | Crystal structure of B. anthracis DHPS with compound 19 | Descriptor: | (2R)-2-(7-amino-4,5-dioxo-1,4,5,6-tetrahydropyrimido[4,5-c]pyridazin-3-yl)propanoic acid, Dihydropteroate Synthase, SULFATE ION | Authors: | Hammoudeh, D, Lee, R.E, White, S.W. | Deposit date: | 2012-01-12 | Release date: | 2012-04-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Structure-Based Design of Novel Pyrimido[4,5-c]pyridazine Derivatives as Dihydropteroate Synthase Inhibitors with Increased Affinity. Chemmedchem, 7, 2012
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7XF3
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![BU of 7xf3 by Molmil](/molmil-images/mine/7xf3) | The structure of HLA-B*1501/BM58-66AF9 | Descriptor: | 9-mer peptide from Matrix protein 1, Beta-2-microglobulin, MHC class I antigen | Authors: | Zhao, Y.Z, Xiao, W.L, Wu, Y.N, Fan, W.F, Yue, C, Zhang, Q.X, Zhang, D.N, Yuan, X.J, Yao, S.J, Liu, S, Li, M, Wang, P.Y, Zhang, H.J, Zhang, J, Zhao, M, Zheng, X.Q, Liu, W.J, Gao, G.F, Liu, W.L. | Deposit date: | 2022-03-31 | Release date: | 2023-02-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Parallel T Cell Immunogenic Regions in Influenza B and A Viruses with Distinct Nuclear Export Signal Functions: The Balance between Viral Life Cycle and Immune Escape. J Immunol., 210, 2023
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1VBS
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![BU of 1vbs by Molmil](/molmil-images/mine/1vbs) | STRUCTURE OF CYCLOPHILIN COMPLEXED WITH (D)ALA CONTAINING TETRAPEPTIDE | Descriptor: | CYCLOPHILIN A, TETRAPEPTIDE | Authors: | Zhao, Y, Chen, Y, Schutkowski, M, Fischer, G, Ke, H. | Deposit date: | 1998-06-16 | Release date: | 1999-01-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mapping the stereospecificity of peptidyl prolyl cis/trans isomerases. FEBS Lett., 432, 1998
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7X4B
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![BU of 7x4b by Molmil](/molmil-images/mine/7x4b) | Crystal Structure of An Anti-CRISPR Protein | Descriptor: | Anti-CRISPR protein (AcrIIC1), SULFATE ION | Authors: | Hu, J, Zhang, S, Gao, J.Y, Liu, X, Liu, J. | Deposit date: | 2022-03-02 | Release date: | 2022-10-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | A redox switch regulates the assembly and anti-CRISPR activity of AcrIIC1. Nat Commun, 13, 2022
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6KZO
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![BU of 6kzo by Molmil](/molmil-images/mine/6kzo) | membrane protein | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Yan, N. | Deposit date: | 2019-09-25 | Release date: | 2019-12-18 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures of apo and antagonist-bound human Cav3.1. Nature, 576, 2019
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6IWT
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![BU of 6iwt by Molmil](/molmil-images/mine/6iwt) | |
4Z7L
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![BU of 4z7l by Molmil](/molmil-images/mine/4z7l) | Crystal structure of Cas6b | Descriptor: | Cas6b, RNA (5'-R(*GP*CP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*GP*C)-3'), SULFATE ION | Authors: | Li, H. | Deposit date: | 2015-04-07 | Release date: | 2016-04-13 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.503 Å) | Cite: | A Non-Stem-Loop CRISPR RNA Is Processed by Dual Binding Cas6. Structure, 24, 2016
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4Z7K
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![BU of 4z7k by Molmil](/molmil-images/mine/4z7k) | |
8J9Z
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![BU of 8j9z by Molmil](/molmil-images/mine/8j9z) | |
8J9Y
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![BU of 8j9y by Molmil](/molmil-images/mine/8j9y) | |
7C72
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![BU of 7c72 by Molmil](/molmil-images/mine/7c72) | Structure of a mycobacterium tuberculosis puromycin-hydrolyzing peptidase | Descriptor: | D-MALATE, GLYCEROL, Prolyl oligopeptidase | Authors: | Ruiz-Carrillo, D, Zhao, Y.H, Feng, Q, Zhou, X, Zhang, Y, Jiang, J, Lukman, M. | Deposit date: | 2020-05-22 | Release date: | 2021-03-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.00004458 Å) | Cite: | Mycobacterium tuberculosis puromycin hydrolase displays a prolyl oligopeptidase fold and an acyl aminopeptidase activity. Proteins, 89, 2021
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7DYN
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![BU of 7dyn by Molmil](/molmil-images/mine/7dyn) | Phosphorylation of MHC I peptide | Descriptor: | ARG-ARG-PHE-SEP-ARG-SEP-PRO-ILE-ARG-ARG, Beta-2-microglobulin, MHC class I antigen | Authors: | Sun, M.W, Feng, L, Qi, J.X, Liu, W.J. | Deposit date: | 2021-01-22 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Phosphosite-dependent presentation of dual phosphorylated peptides by MHC class I molecules. Iscience, 25, 2022
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7CIS
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![BU of 7cis by Molmil](/molmil-images/mine/7cis) | Peptide modification of MHC class I molecules | Descriptor: | ARG-ARG-PHE-SEP-ARG-SEP-PRO-ILE-ARG, Beta-2-microglobulin, MHC class I antigen | Authors: | Sun, M.W, Feng, L, Qi, J.X, Liu, W.J, Gao, G.F. | Deposit date: | 2020-07-08 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Phosphosite-dependent presentation of dual phosphorylated peptides by MHC class I molecules. Iscience, 25, 2022
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7CIR
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![BU of 7cir by Molmil](/molmil-images/mine/7cir) | Peptide phosphorylation modification of MHC class I molecules | Descriptor: | ARG-ARG-PHE-SEP-ARG-SER-PRO-ILE-ARG-ARG, Beta-2-microglobulin, MHC class I antigen | Authors: | Sun, M.W, Feng, L, Qi, J.X, Liu, W.J, Gao, G.F. | Deposit date: | 2020-07-08 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Phosphosite-dependent presentation of dual phosphorylated peptides by MHC class I molecules. Iscience, 25, 2022
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7CIQ
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![BU of 7ciq by Molmil](/molmil-images/mine/7ciq) | Phosphorylation modification of MHC I polypeptide | Descriptor: | ARG-ARG-PHE-SER-ARG-SER-PRO-ILE-ARG-ARG, Beta-2-microglobulin, MHC class I antigen | Authors: | Sun, M.W, Feng, L, Qi, J.X, Liu, W.J, Gao, G.F. | Deposit date: | 2020-07-08 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Phosphosite-dependent presentation of dual phosphorylated peptides by MHC class I molecules. Iscience, 25, 2022
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8SAI
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![BU of 8sai by Molmil](/molmil-images/mine/8sai) | Cryo-EM structure of GPR34-Gi complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Yong, X.H, Zhao, C, Yan, W, Shao, Z.H. | Deposit date: | 2023-04-01 | Release date: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Cryo-EM structures of human GPR34 enable the identification of selective antagonists. Proc.Natl.Acad.Sci.USA, 120, 2023
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8GPK
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![BU of 8gpk by Molmil](/molmil-images/mine/8gpk) | |
8GP5
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![BU of 8gp5 by Molmil](/molmil-images/mine/8gp5) | Structure of X18 UFO protomer in complex with F6 Fab VHVL domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, F6 Fab VH domain, ... | Authors: | Niu, J, Xu, Y.W, Yang, B. | Deposit date: | 2022-08-25 | Release date: | 2023-08-09 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (4.05 Å) | Cite: | Structures and immune recognition of Env trimers from two Asia prevalent HIV-1 CRFs. Nat Commun, 14, 2023
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8GPI
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![BU of 8gpi by Molmil](/molmil-images/mine/8gpi) | HIV-1 Env X18 UFO in complex with 8ANC195 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 Fab heavy chain, ... | Authors: | Niu, J, Xu, Y.W, Yang, B. | Deposit date: | 2022-08-26 | Release date: | 2023-08-09 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structures and immune recognition of Env trimers from two Asia prevalent HIV-1 CRFs. Nat Commun, 14, 2023
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4R5Y
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![BU of 4r5y by Molmil](/molmil-images/mine/4r5y) | The complex structure of Braf V600E kinase domain with a novel Braf inhibitor | Descriptor: | 5-({(1R,1aS,6bR)-1-[5-(trifluoromethyl)-1H-benzimidazol-2-yl]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl}oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one, Serine/threonine-protein kinase B-raf | Authors: | Feng, Y, Peng, H, Zhang, Y, Liu, Y, Wei, M. | Deposit date: | 2014-08-22 | Release date: | 2016-02-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | BGB-283, a Novel RAF Kinase and EGFR Inhibitor, Displays Potent Antitumor Activity in BRAF-Mutated Colorectal Cancers. Mol.Cancer Ther., 14, 2015
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6K4V
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![BU of 6k4v by Molmil](/molmil-images/mine/6k4v) | The solution structure of the smart chimeric peptide G6 | Descriptor: | smart chimeric peptide G6 | Authors: | Wang, J.H, Liu, X.H. | Deposit date: | 2019-05-27 | Release date: | 2019-06-12 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Development of chimeric peptides to facilitate the neutralisation of lipopolysaccharides during bactericidal targeting of multidrug-resistant Escherichia coli. Commun Biol, 3, 2020
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6K4W
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![BU of 6k4w by Molmil](/molmil-images/mine/6k4w) | smart chimeric peptide SCP-A6 | Descriptor: | SCP-A6 | Authors: | Wang, J.H, Liu, X.H. | Deposit date: | 2019-05-27 | Release date: | 2019-06-12 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Development of chimeric peptides to facilitate the neutralisation of lipopolysaccharides during bactericidal targeting of multidrug-resistant Escherichia coli. Commun Biol, 3, 2020
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5GT1
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![BU of 5gt1 by Molmil](/molmil-images/mine/5gt1) | crystal structure of cbpa from L. salivarius REN | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Choline binding protein A, ... | Authors: | Jiang, L, Ren, F. | Deposit date: | 2016-08-18 | Release date: | 2017-07-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The Adhesion of Lactobacillus salivarius REN to a Human Intestinal Epithelial Cell Line Requires S-layer Proteins Sci Rep, 7, 2017
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