4ZS8
| Crystal structure of ligand-free, full length DasR | Descriptor: | 1,2-ETHANEDIOL, HTH-type transcriptional repressor DasR | Authors: | Fillenberg, S.B, Muller, Y.A. | Deposit date: | 2015-05-13 | Release date: | 2016-06-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structures of the Global Regulator DasR from Streptomyces coelicolor: Implications for the Allosteric Regulation of GntR/HutC Repressors. Plos One, 11, 2016
|
|
4ZSK
| |
1KDM
| THE CRYSTAL STRUCTURE OF THE HUMAN SEX HORMONE-BINDING GLOBULIN (TETRAGONAL CRYSTAL FORM) | Descriptor: | 5-ALPHA-DIHYDROTESTOSTERONE, CALCIUM ION, sex hormone-binding globulin | Authors: | Grishkovskaya, I, Avvakumov, G.V, Hammond, G.L, Muller, Y.A. | Deposit date: | 2001-11-13 | Release date: | 2002-05-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Resolution of a disordered region at the entrance of the human sex hormone-binding globulin steroid-binding site. J.Mol.Biol., 318, 2002
|
|
1LHU
| CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH ESTRADIOL | Descriptor: | CALCIUM ION, ESTRADIOL, SEX HORMONE-BINDING GLOBULIN | Authors: | Grishkovskaya, I, Avvakumov, G.V, Hammond, G.L, Catalano, M.G, Muller, Y.A. | Deposit date: | 2002-04-17 | Release date: | 2002-10-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Steroid Ligands Bind Human Sex Hormone-binding Globulin in Specific Orientations and Produce Distinct Changes in Protein Conformation J.Biol.Chem., 277, 2002
|
|
7PAB
| Varicella zoster Orf24-Orf27 nuclear egress complex | Descriptor: | Nuclear egress protein 2,Nuclear egress protein 1, SULFATE ION, ZINC ION | Authors: | Schweininger, J, Muller, Y.A. | Deposit date: | 2021-07-29 | Release date: | 2022-01-19 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of the varicella-zoster Orf24-Orf27 nuclear egress complex spotlights multiple determinants of herpesvirus subfamily specificity. J.Biol.Chem., 298, 2022
|
|
1LHW
| CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH 2-METHOXYESTRADIOL | Descriptor: | 1,3,5(10)-ESTRATRIEN-2,3,17-BETA-TRIOL 2-METHYL ETHER, CALCIUM ION, ISOPROPYL ALCOHOL, ... | Authors: | Avvakumov, G.V, Grishkovskaya, I, Muller, Y.A, Hammond, G.L. | Deposit date: | 2002-04-17 | Release date: | 2002-10-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of human sex hormone-binding globulin in complex with 2-methoxyestradiol reveals the molecular basis for high affinity interactions with C-2 derivatives of estradiol. J.Biol.Chem., 277, 2002
|
|
1LHO
| CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH 5ALPHA-ANDROSTANE-3BETA,17BETA-DIOL | Descriptor: | 5-ALPHA-ANDROSTANE-3-BETA,17BETA-DIOL, CALCIUM ION, SEX HORMONE-BINDING GLOBULIN | Authors: | Grishkovskaya, I, Avvakumov, G.V, Hammond, G.L, Catalano, M.G, Muller, Y.A. | Deposit date: | 2002-04-17 | Release date: | 2002-10-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Steroid Ligands Bind Human Sex Hormone-binding Globulin in Specific Orientations and Produce Distinct Changes in Protein Conformation J.Biol.Chem., 277, 2002
|
|
1LHV
| CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH NORGESTREL | Descriptor: | 13-BETA-ETHYL-17-ALPHA-ETHYNYL-17-BETA-HYDROXYGON-4-EN-3-ONE, CALCIUM ION, ISOPROPYL ALCOHOL, ... | Authors: | Grishkovskaya, I, Avvakumov, G.V, Hammond, G.L, Catalano, M.G, Muller, Y.A. | Deposit date: | 2002-04-17 | Release date: | 2002-10-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Steroid Ligands Bind Human Sex Hormone-binding Globulin in Specific Orientations and Produce Distinct Changes in Protein Conformation J.Biol.Chem., 277, 2002
|
|
1JPT
| Crystal Structure of Fab D3H44 | Descriptor: | immunoglobulin Fab D3H44, heavy chain, immunoglobulin Fab D3h44, ... | Authors: | Faelber, K, Kirchhofer, D, Presta, L, Kelley, R.F, Muller, Y.A. | Deposit date: | 2001-08-03 | Release date: | 2002-02-03 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The 1.85 A resolution crystal structures of tissue factor in complex with humanized Fab D3h44 and of free humanized Fab D3h44: revisiting the solvation of antigen combining sites. J.Mol.Biol., 313, 2001
|
|
1K6Q
| Crystal structure of antibody Fab fragment D3 | Descriptor: | immunoglobulin Fab D3, heavy chain, light chain | Authors: | Faelber, K, Kelley, R.F, Kirchhofer, D, Muller, Y.A. | Deposit date: | 2001-10-17 | Release date: | 2002-04-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The crystal structure of murine Fab D3 at 2.4 A resolution in comparison with the humanised Fab D3h44 (1.85A) provides structural insight into the humanisation process of the D3 anti-tissue factor antibody To be Published
|
|
1LHN
| CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH 5ALPHA-ANDROSTANE-3BETA,17ALPHA-DIOL | Descriptor: | 5-ALPHA-ANDROSTANE-3-BETA,17-ALPHA-DIOL, CALCIUM ION, SEX HORMONE-BINDING GLOBULIN, ... | Authors: | Grishkovskaya, I, Avvakumov, G.V, Hammond, G.L, Catalano, M.G, Muller, Y.A. | Deposit date: | 2002-04-17 | Release date: | 2002-10-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Steroid Ligands Bind Human Sex Hormone-binding Globulin in Specific Orientations and Produce Distinct Changes in Protein Conformation J.Biol.Chem., 277, 2002
|
|
1KDK
| THE STRUCTURE OF THE N-TERMINAL LG DOMAIN OF SHBG IN CRYSTALS SOAKED WITH EDTA | Descriptor: | 5-ALPHA-DIHYDROTESTOSTERONE, Sex Hormone-Binding Globulin | Authors: | Grishkovskaya, I, Avvakumov, G.V, Hammond, G.L, Muller, Y.A. | Deposit date: | 2001-11-13 | Release date: | 2002-05-15 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Resolution of a disordered region at the entrance of the human sex hormone-binding globulin steroid-binding site. J.Mol.Biol., 318, 2002
|
|
2V6G
| Structure of Progesterone 5beta-Reductase from Digitalis Lanata in complex with NADP | Descriptor: | CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROGESTERONE 5-BETA-REDUCTASE, ... | Authors: | Thorn, A, Egerer-Sieber, C, Jaeger, C, Herl, V, Mueller-Uri, F, Kreis, W, Muller, Y.A. | Deposit date: | 2007-07-18 | Release date: | 2007-11-20 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Crystal Structure of Progesterone 5{Beta}-Reductase from Digitalis Lanata Defines a Novel Class of Short Chain Dehydrogenases/Reductases. J.Biol.Chem., 283, 2008
|
|
2WEX
| Crystal structure of human apoM in complex with glycerol 1- myristic acid | Descriptor: | (2R)-2,3-dihydroxypropyl tetradecanoate, 1,2-ETHANEDIOL, APOLIPOPROTEIN M | Authors: | Sevvana, M, Ahnstrom, J, Egerer-Sieber, C, Dahlback, B, Muller, Y.A. | Deposit date: | 2009-04-02 | Release date: | 2009-09-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Serendipitous Fatty Acid Binding Reveals the Structural Determinants for Ligand Recognition in Apolipoprotein M. J.Mol.Biol., 393, 2009
|
|
2V95
| Structure of Corticosteroid-Binding Globulin in complex with Cortisol | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN | Authors: | Klieber, M.A, Muller, Y.A. | Deposit date: | 2007-08-21 | Release date: | 2007-09-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Corticosteroid-Binding Globulin: Structural Basis for Steroid Transport and Proteinase-Triggered Release J.Biol.Chem., 282, 2007
|
|
6HGD
| |
6HGG
| Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with cortisol | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin | Authors: | Schmidt, K, Muller, Y.A. | Deposit date: | 2018-08-23 | Release date: | 2019-05-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.787 Å) | Cite: | NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
|
|
6HGM
| |
6HGF
| Crystal structure of Alpha1-antichymotrypsin variant NewBG-II: a new binding globulin in complex with cortisol | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin | Authors: | Schmidt, K, Muller, Y.A. | Deposit date: | 2018-08-23 | Release date: | 2019-05-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.651 Å) | Cite: | NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
|
|
6HGH
| |
2WV0
| Crystal structure of the GntR-HutC family member YvoA from Bacillus subtilis | Descriptor: | HTH-TYPE TRANSCRIPTIONAL REPRESSOR YVOA, SULFATE ION | Authors: | Resch, M, Schiltz, E, Titgemeyer, F, Muller, Y.A. | Deposit date: | 2009-10-12 | Release date: | 2010-01-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Insight Into the Induction Mechanism of the Gntr/Hutc Bacterial Transcription Regulator Yvoa Nucleic Acids Res., 38, 2010
|
|
2WEW
| Crystal structure of human apoM in complex with myristic acid | Descriptor: | 1,2-ETHANEDIOL, APOLIPOPROTEIN M, MYRISTIC ACID | Authors: | Sevvana, M, Ahnstrom, J, Egerer-Sieber, C, Dahlback, B, Muller, Y.A. | Deposit date: | 2009-04-02 | Release date: | 2009-09-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Serendipitous Fatty Acid Binding Reveals the Structural Determinants for Ligand Recognition in Apolipoprotein M. J.Mol.Biol., 393, 2009
|
|
6GY3
| Crystal Structure of C. glutamicum AmtR bound to glnA operator DNA | Descriptor: | AmtR protein, DNA (5'-D(*GP*TP*CP*TP*AP*TP*AP*GP*AP*TP*CP*GP*AP*TP*AP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*TP*AP*TP*CP*GP*AP*TP*CP*TP*AP*TP*AP*GP*AP*C)-3') | Authors: | Sevvana, M, Muller, Y.A. | Deposit date: | 2018-06-28 | Release date: | 2019-07-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | The role of DNA flexibility in transcription regulator AmtR-DNA interaction To be published
|
|
2XGD
| Crystal structure of a designed homodimeric variant T-A(L)A(L) of the tetracycline repressor | Descriptor: | CHLORIDE ION, TETRACYCLINE REPRESSOR PROTEIN CLASS B FROM TRANSPOSON TN10, TETRACYCLINE REPRESSOR PROTEIN CLASS D | Authors: | Stiebritz, M.T, Wengrzik, S, Richter, J.P, Muller, Y.A. | Deposit date: | 2010-06-03 | Release date: | 2010-09-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Computational Design of a Chain-Specific Tetracycline Repressor Heterodimer. J.Mol.Biol., 403, 2010
|
|
2XGC
| Crystal structure of a designed heterodimeric variant T-A(I)B of the tetracycline repressor | Descriptor: | TETRACYCLINE REPRESSOR PROTEIN CLASS B FROM TRANSPOSON TN10, TETRACYCLINE REPRESSOR PROTEIN CLASS D | Authors: | Stiebritz, M.T, Wengrzik, S, Richter, J.P, Muller, Y.A. | Deposit date: | 2010-06-03 | Release date: | 2010-09-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Computational Design of a Chain-Specific Tetracycline Repressor Heterodimer. J.Mol.Biol., 403, 2010
|
|