1JPT

Crystal Structure of Fab D3H44

Summary for 1JPT

Related1JPS
Descriptorimmunoglobulin Fab D3h44, light chain, immunoglobulin Fab D3H44, heavy chain (3 entities in total)
Functional Keywordsantigen-antibody recognition, humanized antibody, blood coagulation, immune system
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight47566.91
Authors
Faelber, K.,Kirchhofer, D.,Presta, L.,Kelley, R.F.,Muller, Y.A. (deposition date: 2001-08-03, release date: 2002-02-03, Last modification date: 2017-10-04)
Primary citation
Faelber, K.,Kirchhofer, D.,Presta, L.,Kelley, R.F.,Muller, Y.A.
The 1.85 A resolution crystal structures of tissue factor in complex with humanized Fab D3h44 and of free humanized Fab D3h44: revisiting the solvation of antigen combining sites.
J.Mol.Biol., 313:83-97, 2001
PubMed: 11601848 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.2001.5036
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.85 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2285 0.2% 1.7% 1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171588
PDB entries from 2020-11-25