2V6G

Structure of Progesterone 5beta-Reductase from Digitalis Lanata in complex with NADP

Summary for 2V6G

Entry DOI	10.2210/pdb2v6g/pdb
Related	2V6F
Descriptor	PROGESTERONE 5-BETA-REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	tyrosine-dependent oxidoreductase, oxidoreductase, sdr, reductase, cardenolides, cardiac glycosides
Biological source	DIGITALIS LANATA (FOXGLOVE)
Total number of polymer chains	1
Total formula weight	42129.62
Authors	Thorn, A.,Egerer-Sieber, C.,Jaeger, C.,Herl, V.,Mueller-Uri, F.,Kreis, W.,Muller, Y.A. (deposition date: 2007-07-18, release date: 2007-11-20, Last modification date: 2011-07-13)
Primary citation	Thorn, A.,Egerer-Sieber, C.,Jaeger, C.,Herl, V.,Mueller-Uri, F.,Kreis, W.,Muller, Y.A. The Crystal Structure of Progesterone 5{Beta}-Reductase from Digitalis Lanata Defines a Novel Class of Short Chain Dehydrogenases/Reductases. J.Biol.Chem., 283:17260-, 2008 Cited by PubMed: 18032383 DOI: 10.1074/JBC.M706185200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation