2V6G
Structure of Progesterone 5beta-Reductase from Digitalis Lanata in complex with NADP
Summary for 2V6G
Entry DOI | 10.2210/pdb2v6g/pdb |
Related | 2V6F |
Descriptor | PROGESTERONE 5-BETA-REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | tyrosine-dependent oxidoreductase, oxidoreductase, sdr, reductase, cardenolides, cardiac glycosides |
Biological source | DIGITALIS LANATA (FOXGLOVE) |
Total number of polymer chains | 1 |
Total formula weight | 42129.62 |
Authors | Thorn, A.,Egerer-Sieber, C.,Jaeger, C.,Herl, V.,Mueller-Uri, F.,Kreis, W.,Muller, Y.A. (deposition date: 2007-07-18, release date: 2007-11-20, Last modification date: 2024-05-01) |
Primary citation | Thorn, A.,Egerer-Sieber, C.,Jaeger, C.,Herl, V.,Mueller-Uri, F.,Kreis, W.,Muller, Y.A. The Crystal Structure of Progesterone 5{Beta}-Reductase from Digitalis Lanata Defines a Novel Class of Short Chain Dehydrogenases/Reductases. J.Biol.Chem., 283:17260-, 2008 Cited by PubMed: 18032383DOI: 10.1074/JBC.M706185200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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