1YY9
 
 | | Structure of the extracellular domain of the epidermal growth factor receptor in complex with the Fab fragment of cetuximab/Erbitux/IMC-C225 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab Heavy chain, ... | | Authors: | Li, S, Schmitz, K.R, Jeffrey, P.D, Wiltzius, J.J.W, Kussie, P, Ferguson, K.M. | | Deposit date: | 2005-02-24 | | Release date: | 2005-04-26 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.605 Å) | | Cite: | Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
Cancer Cell, 7, 2005
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3C5W
 | | Complex between PP2A-specific methylesterase PME-1 and PP2A core enzyme | | Descriptor: | PP2A A subunit, PP2A C subunit, PP2A-specific methylesterase PME-1 | | Authors: | Xing, Y, Li, Z, Chen, Y, Stock, J, Jeffrey, P.D, Shi, Y. | | Deposit date: | 2008-02-01 | | Release date: | 2008-04-15 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural mechanism of demethylation and inactivation of protein phosphatase 2A.
Cell(Cambridge,Mass.), 133, 2008
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3BOB
 | | Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 2 | | Descriptor: | CADMIUM ION, Cadmium-specific carbonic anhydrase | | Authors: | Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M. | | Deposit date: | 2007-12-17 | | Release date: | 2008-01-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.
Nature, 452, 2008
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3BOC
 | | Carbonic anhydrase from marine diatom Thalassiosira weissflogii- zinc bound domain 2 (CDCA1-R2) | | Descriptor: | Cadmium-specific carbonic anhydrase, ZINC ION | | Authors: | Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M. | | Deposit date: | 2007-12-17 | | Release date: | 2008-01-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.
Nature, 452, 2008
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3BOE
 | | Carbonic anhydrase from marine diatom Thalassiosira weissflogii- cadmium bound domain 2 with acetate (CDCA1-R2) | | Descriptor: | ACETATE ION, CADMIUM ION, Cadmium-specific carbonic anhydrase | | Authors: | Xu, Y, Feng, L, Jeffrey, P.D, Shi, Y, Morel, F.M.M. | | Deposit date: | 2007-12-17 | | Release date: | 2008-01-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.
Nature, 452, 2008
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4CEV
 | | ARGINASE FROM BACILLUS CALDEVELOX, L-ORNITHINE COMPLEX | | Descriptor: | GUANIDINE, L-ornithine, MANGANESE (II) ION, ... | | Authors: | Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. | | Deposit date: | 1999-03-15 | | Release date: | 1999-04-16 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
Structure Fold.Des., 7, 1999
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6PRK
 | | X-ray Crystal Structure of Bacillus subtilis RicA in complex with RicF | | Descriptor: | RicA, RicF | | Authors: | Khaja, F.T, Jeffrey, P.D, Neiditch, M.B, Dubnau, D. | | Deposit date: | 2019-07-10 | | Release date: | 2019-10-02 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure-Function Studies of the Bacillus subtilis Ric Proteins Identify the Fe-S Cluster-Ligating Residues and Their Roles in Development and RNA Processing.
Mbio, 10, 2019
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2CEV
 | | ARGINASE FROM BACILLUS CALDEVELOX, NATIVE STRUCTURE AT PH 8.5 | | Descriptor: | GUANIDINE, MANGANESE (II) ION, PROTEIN (ARGINASE) | | Authors: | Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. | | Deposit date: | 1999-03-10 | | Release date: | 1999-04-16 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
Structure Fold.Des., 7, 1999
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2AYN
 | | Structure of USP14, a proteasome-associated deubiquitinating enzyme | | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 14 | | Authors: | Hu, M, Li, P, Jeffrey, P.D, Shi, Y. | | Deposit date: | 2005-09-07 | | Release date: | 2005-10-18 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14.
Embo J., 24, 2005
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2AYO
 | | Structure of USP14 bound to ubquitin aldehyde | | Descriptor: | Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 14 | | Authors: | Hu, M, Li, P, Jeffrey, P.D, Shi, Y. | | Deposit date: | 2005-09-07 | | Release date: | 2005-10-18 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14.
Embo J., 24, 2005
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2F1W
 | | Crystal structure of the TRAF-like domain of HAUSP/USP7 | | Descriptor: | CALCIUM ION, Ubiquitin carboxyl-terminal hydrolase 7 | | Authors: | Hu, M, Gu, L, Jeffrey, P.D, Shi, Y. | | Deposit date: | 2005-11-15 | | Release date: | 2006-02-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway.
Plos Biol., 4, 2006
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6WC3
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4KMO
 | | Crystal Structure of the Vps33-Vps16 HOPS subcomplex from Chaetomium thermophilum | | Descriptor: | Putative vacuolar protein sorting-associated protein, SULFATE ION, Small conjugating protein ligase-like protein | | Authors: | Baker, R.W, Jeffrey, P.D, Hughson, F.M. | | Deposit date: | 2013-05-08 | | Release date: | 2013-06-26 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*
Plos One, 8, 2013
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4L9O
 | | Crystal Structure of the Sec13-Sec16 blade-inserted complex from Pichia pastoris | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | | Authors: | McMahon, C, Jeffrey, P.D, Hughson, F.M. | | Deposit date: | 2013-06-18 | | Release date: | 2013-10-02 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Sec16 influences transitional ER sites by regulating rather than organizing COPII.
Mol Biol Cell, 24, 2013
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4JC8
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4M9R
 | | Crystal structure of CED-3 | | Descriptor: | Cell death protein 3 | | Authors: | Xu, Y, Jeffrey, P.D, Shi, Y.G. | | Deposit date: | 2013-08-15 | | Release date: | 2013-10-09 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.656 Å) | | Cite: | Mechanistic insights into CED-4-mediated activation of CED-3
Genes Dev., 27, 2013
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8CUK
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5CEV
 | | ARGINASE FROM BACILLUS CALDEVELOX, L-LYSINE COMPLEX | | Descriptor: | GUANIDINE, LYSINE, MANGANESE (II) ION, ... | | Authors: | Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. | | Deposit date: | 1999-03-16 | | Release date: | 1999-04-16 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
Structure Fold.Des., 7, 1999
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5EP0
 | | Quorum-Sensing Signal Integrator LuxO - Receiver+Catalytic Domains | | Descriptor: | 1,2-ETHANEDIOL, Putative repressor protein luxO, SULFATE ION | | Authors: | Shah, T, Selcuk, H.B, Jeffrey, P.D, Hughson, F.M. | | Deposit date: | 2015-11-11 | | Release date: | 2016-04-20 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO.
Plos Biol., 14, 2016
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5EP2
 | | Quorum-Sensing Signal Integrator LuxO - Catalytic Domain in Complex with AzaU Inhibitor | | Descriptor: | 2,2-dimethylpropyl 2-[[3,5-bis(oxidanylidene)-2~{H}-1,2,4-triazin-6-yl]sulfanyl]ethanoate, ACETATE ION, Putative repressor protein luxO | | Authors: | Shah, T, Selcuk, H.B, Jeffrey, P.D, Hughson, F.M. | | Deposit date: | 2015-11-11 | | Release date: | 2016-04-20 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.421 Å) | | Cite: | Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO.
Plos Biol., 14, 2016
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5EP1
 | | Quorum-Sensing Signal Integrator LuxO - Catalytic Domain | | Descriptor: | ACETATE ION, Putative repressor protein luxO | | Authors: | Shah, T, Selcuk, H.B, Jeffrey, P.D, Hughson, F.M. | | Deposit date: | 2015-11-11 | | Release date: | 2016-04-20 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO.
Plos Biol., 14, 2016
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5EP4
 | | Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO | | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Shah, T, Selcuk, H.B, Jeffrey, P.D, Hughson, F.M. | | Deposit date: | 2015-11-11 | | Release date: | 2016-04-20 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO.
Plos Biol., 14, 2016
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5EP3
 | | Quorum-Sensing Signal Integrator LuxO - Catalytic Domain Bound to CV-133 Inhibitor | | Descriptor: | 1,2-ETHANEDIOL, 2,2-dimethylpropyl 2-[(3-oxidanylidene-5-sulfanylidene-2~{H}-1,2,4-triazin-6-yl)amino]ethanoate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | Authors: | Shah, T, Selcuk, H.B, Jeffrey, P.D, Hughson, F.M. | | Deposit date: | 2015-11-11 | | Release date: | 2016-04-20 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO.
Plos Biol., 14, 2016
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2F1Y
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2F1X
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