1CJF
| PROFILIN BINDS PROLINE-RICH LIGANDS IN TWO DISTINCT AMIDE BACKBONE ORIENTATIONS | Descriptor: | 7-HYDROXY-4-METHYL-3-(2-HYDROXY-ETHYL)COUMARIN, PROTEIN (HUMAN PLATELET PROFILIN), PROTEIN (PROLINE PEPTIDE) | Authors: | Mahoney, N.M, Fedorov, A.A, Fedorov, E, Rozwarski, D.A, Almo, S.C. | Deposit date: | 1999-04-13 | Release date: | 1999-07-07 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Profilin binds proline-rich ligands in two distinct amide backbone orientations. Nat.Struct.Biol., 6, 1999
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1CQA
| BIRCH POLLEN PROFILIN | Descriptor: | PROFILIN | Authors: | Fedorov, A.A, Ball, T, Mahoney, N.M, Valenta, R, Almo, S.C. | Deposit date: | 1996-07-26 | Release date: | 1997-02-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The molecular basis for allergen cross-reactivity: crystal structure and IgE-epitope mapping of birch pollen profilin. Structure, 5, 1997
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1BZY
| HUMAN HGPRTASE WITH TRANSITION STATE INHIBITOR | Descriptor: | HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, MAGNESIUM ION, PHOSPHORIC ACID MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN-2-YLMETHYL] ESTER, ... | Authors: | Shi, W, Li, C, Tyler, P.C, Furneaux, R.H, Grubmeyer, C, Schramm, V.L, Almo, S.C. | Deposit date: | 1998-11-05 | Release date: | 1999-06-22 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor. Nat.Struct.Biol., 6, 1999
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1A9S
| BOVINE PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH INOSINE AND SULFATE | Descriptor: | INOSINE, PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION | Authors: | Mao, C, Cook, W.J, Zhou, M, Fedorov, A.A, Almo, S.C, Ealick, S.E. | Deposit date: | 1998-04-10 | Release date: | 1998-07-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues. Biochemistry, 37, 1998
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1DQP
| CRYSTAL STRUCTURE OF GIARDIA GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH IMMUCILLING | Descriptor: | 1,4-DIDEOXY-1,4-IMINO-1-(S)-(9-DEAZAGUANIN-9-YL)-D-RIBITOL, GUANINE PHOSPHORIBOSYLTRANSFERASE, ISOPROPYL ALCOHOL | Authors: | Shi, W, Munagala, N.R, Wang, C.C, Li, C.M, Tyler, P.C, Furneaux, R.H, Grubmeyer, C, Schramm, V.L, Almo, S.C. | Deposit date: | 2000-01-04 | Release date: | 2000-07-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,). Biochemistry, 39, 2000
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1DFC
| CRYSTAL STRUCTURE OF HUMAN FASCIN, AN ACTIN-CROSSLINKING PROTEIN | Descriptor: | FASCIN | Authors: | Fedorov, A.A, Fedorov, E.V, Ono, S, Matsumura, F, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 1999-11-18 | Release date: | 2000-11-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure, evolutionary conservation, and conformational dynamics of Homo sapiens fascin-1, an F-actin crosslinking protein. J.Mol.Biol., 400, 2010
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1DQT
| THE CRYSTAL STRUCTURE OF MURINE CTLA4 (CD152) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, CYTOTOXIC T LYMPHOCYTE ASSOCIATED ANTIGEN 4 | Authors: | Ostrov, D.A, Shi, W, Schwartz, J.C, Almo, S.C, Nathenson, S.G. | Deposit date: | 2000-01-05 | Release date: | 2000-10-27 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of murine CTLA-4 and its role in modulating T cell responsiveness. Science, 290, 2000
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1DQN
| CRYSTAL STRUCTURE OF GIARDIA GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH A TRANSITION STATE ANALOGUE | Descriptor: | GUANINE PHOSPHORIBOSYLTRANSFERASE, ISOPROPYL ALCOHOL, MAGNESIUM ION, ... | Authors: | Shi, W, Munagala, N.R, Wang, C.C, Li, C.M, Tyler, P.C, Furneaux, R.H, Grubmeyer, C, Schramm, V.L, Almo, S.C. | Deposit date: | 2000-01-04 | Release date: | 2000-07-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,). Biochemistry, 39, 2000
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1A9R
| BOVINE PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH HYPOXANTHINE AND SULFATE | Descriptor: | HYPOXANTHINE, PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION | Authors: | Mao, C, Cook, W.J, Zhou, M, Fedorov, A.A, Almo, S.C, Ealick, S.E. | Deposit date: | 1998-04-10 | Release date: | 1998-07-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues. Biochemistry, 37, 1998
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1AAX
| CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH TWO BIS(PARA-PHOSPHOPHENYL)METHANE (BPPM) MOLECULES | Descriptor: | 4-PHOSPHONOOXY-PHENYL-METHYL-[4-PHOSPHONOOXY]BENZEN, MAGNESIUM ION, PROTEIN TYROSINE PHOSPHATASE 1B | Authors: | Puius, Y.A, Zhao, Y, Sullivan, M, Lawrence, D, Almo, S.C, Zhang, Z.-Y. | Deposit date: | 1997-01-16 | Release date: | 1998-03-04 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design. Proc.Natl.Acad.Sci.USA, 94, 1997
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1CJB
| MALARIAL PURINE PHOSPHORIBOSYLTRANSFERASE | Descriptor: | (1S)-1(9-DEAZAHYPOXANTHIN-9YL)1,4-DIDEOXY-1,4-IMINO-D-RIBITOL-5-PHOSPHATE, MAGNESIUM ION, PROTEIN (HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE), ... | Authors: | Shi, W, Li, C.M, Tyler, P.C, Furneaux, R.H, Cahill, S.M, Girvin, M.E, Grubmeyer, C, Schramm, V.L, Almo, S.C. | Deposit date: | 1999-04-08 | Release date: | 1999-08-18 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The 2.0 A structure of malarial purine phosphoribosyltransferase in complex with a transition-state analogue inhibitor. Biochemistry, 38, 1999
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1COF
| YEAST COFILIN, ORTHORHOMBIC CRYSTAL FORM | Descriptor: | COFILIN | Authors: | Fedorov, A.A, Lappalainen, P, Fedorov, E.V, Drubin, D.G, Almo, S.C. | Deposit date: | 1996-11-26 | Release date: | 1997-04-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure determination of yeast cofilin. Nat.Struct.Biol., 4, 1997
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1WUE
| Crystal structure of protein GI:29375081, unknown member of enolase superfamily from enterococcus faecalis V583 | Descriptor: | mandelate racemase/muconate lactonizing enzyme family protein | Authors: | Fedorov, A.A, Fedorov, E.V, Yew, W.S, Gerlt, J.A, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2004-12-05 | Release date: | 2004-12-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family Proc.Natl.Acad.Sci.USA, 111, 2014
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1WUF
| Crystal structure of protein GI:16801725, member of Enolase superfamily from Listeria innocua Clip11262 | Descriptor: | MAGNESIUM ION, hypothetical protein lin2664 | Authors: | Fedorov, A.A, Fedorov, E.V, Yew, W.S, Gerlt, J.A, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2004-12-07 | Release date: | 2004-12-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Loss of quaternary structure is associated with rapid sequence divergence in the OSBS family Proc.Natl.Acad.Sci.USA, 111, 2014
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4YO8
| Crystal structure of Helicobacter pylori 5'-methylthioadenosine/S-adenosyl homocysteine nucleosidase (MTAN) complexed with (((4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)(hexyl)amino)methanol | Descriptor: | Aminodeoxyfutalosine nucleosidase, ZINC ION, {[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl](hexyl)amino}methanol | Authors: | Cameron, S.A, Wang, S, Almo, S.C, Schramm, V.L. | Deposit date: | 2015-03-11 | Release date: | 2015-11-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | New Antibiotic Candidates against Helicobacter pylori. J.Am.Chem.Soc., 137, 2015
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1WHP
| ALLERGEN PHL P 2 | Descriptor: | ALLERGEN PHL P 2 | Authors: | Fedorov, A.A, Fedorov, E.V, Dolecek, C, Susani, M, Valenta, R, Almo, S.C. | Deposit date: | 1997-04-04 | Release date: | 1997-07-07 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structure of Phl P 2, a Major Timothy Grass (Phleum Pratense) Pollen Allergen To be Published
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1XM5
| Crystal structure of metal-dependent hydrolase ybeY from E. coli, Pfam UPF0054 | Descriptor: | Hypothetical UPF0054 protein ybeY, NICKEL (II) ION | Authors: | Fedorov, A.A, Fedorov, E.V, Shi, W, Ramagopal, U.A, Thirumuruhan, R, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2004-10-01 | Release date: | 2004-10-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The ybeY protein from Escherichia coli is a metalloprotein. Acta Crystallogr.,Sect.F, 61, 2005
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1YS9
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1YRZ
| Crystal structure of xylan beta-1,4-xylosidase from Bacillus Halodurans C-125 | Descriptor: | xylan beta-1,4-xylosidase | Authors: | Fedorov, A.A, Fedorov, E.V, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2005-02-05 | Release date: | 2005-02-22 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of xylan beta-1,4-xylosidase from Bacillus Halodurans C-125 To be Published
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1YPR
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1YWK
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1YZY
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1Z3A
| Crystal structure of tRNA adenosine deaminase TadA from Escherichia coli | Descriptor: | ZINC ION, tRNA-specific adenosine deaminase | Authors: | Malashkevich, V, Kim, J, Lisbin, M, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2005-03-10 | Release date: | 2006-02-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Structural and kinetic characterization of Escherichia coli TadA, the wobble-specific tRNA deaminase. Biochemistry, 45, 2006
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1Z2I
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1Z4E
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