7DCY
 
 | | Apo form of Mycoplasma genitalium RNase R | | Descriptor: | MAGNESIUM ION, Ribonuclease R | | Authors: | Abula, A, Quan, X, Li, X, Yang, T, Li, T, Chen, Q, Ji, X. | | Deposit date: | 2020-10-27 | | Release date: | 2021-03-17 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.972 Å) | | Cite: | Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation.
Nucleic Acids Res., 49, 2021
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7DIC
 | | Mycoplasma genitalium RNase R in complex with single-stranded RNA | | Descriptor: | MAGNESIUM ION, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), Ribonuclease R | | Authors: | Abula, A, Quan, X, Li, X, Yang, T, Li, T, Chen, Q, Ji, X. | | Deposit date: | 2020-11-18 | | Release date: | 2021-03-17 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.242 Å) | | Cite: | Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation.
Nucleic Acids Res., 49, 2021
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7DOL
 | | Mycoplasma genitalium RNase R in complex with double-stranded RNA | | Descriptor: | MAGNESIUM ION, RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3'), Ribonuclease R | | Authors: | Abula, A, Quan, X, Li, X, Yang, T, Li, T, Chen, Q, Ji, X. | | Deposit date: | 2020-12-14 | | Release date: | 2021-03-17 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.002 Å) | | Cite: | Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation.
Nucleic Acids Res., 49, 2021
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7DID
 | | Mycoplasma genitalium RNase R in complex with ribose methylated single-stranded RNA | | Descriptor: | MAGNESIUM ION, RNA (5'-R(*AP*AP*AP*A)-3'), Ribonuclease R | | Authors: | Abula, A, Quan, X, Li, X, Yang, T, Li, T, Chen, Q, Ji, X. | | Deposit date: | 2020-11-18 | | Release date: | 2021-03-17 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation.
Nucleic Acids Res., 49, 2021
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7URF
 | | Human HHAT H379C in complex with SHH N-terminal peptide | | Descriptor: | 3H02 heavy chain, 3H02 light chain, Digitonin, ... | | Authors: | Liu, Y, Qi, X, Li, X. | | Deposit date: | 2022-04-21 | | Release date: | 2022-07-20 | | Last modified: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Mechanisms and inhibition of Porcupine-mediated Wnt acylation.
Nature, 607, 2022
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7URE
 | | Human PORCN in complex with palmitoleoylated WNT3A peptide | | Descriptor: | 2C11 heavy chain, 2C11 light chain, Digitonin, ... | | Authors: | Liu, Y, Qi, X, Li, X. | | Deposit date: | 2022-04-21 | | Release date: | 2022-07-20 | | Last modified: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.19 Å) | | Cite: | Mechanisms and inhibition of Porcupine-mediated Wnt acylation.
Nature, 607, 2022
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7URC
 | | Human PORCN in complex with LGK974 | | Descriptor: | 2-[(2P)-2',3-dimethyl[2,4'-bipyridin]-5-yl]-N-[(5P)-5-(pyrazin-2-yl)pyridin-2-yl]acetamide, 2C11 heavy chain, 2C11 light chain, ... | | Authors: | Liu, Y, Qi, X, Li, X. | | Deposit date: | 2022-04-21 | | Release date: | 2022-07-20 | | Last modified: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.14 Å) | | Cite: | Mechanisms and inhibition of Porcupine-mediated Wnt acylation.
Nature, 607, 2022
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7URA
 | | Human PORCN in complex with Palmitoleoyl-CoA | | Descriptor: | 2C11 heavy chain, 2C11 light chain, CHOLESTEROL, ... | | Authors: | Liu, Y, Qi, X, Li, X. | | Deposit date: | 2022-04-21 | | Release date: | 2022-07-20 | | Last modified: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.11 Å) | | Cite: | Mechanisms and inhibition of Porcupine-mediated Wnt acylation.
Nature, 607, 2022
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7URD
 | | Human PORCN in complex with LGK974 and WNT3A peptide | | Descriptor: | 2-[(2P)-2',3-dimethyl[2,4'-bipyridin]-5-yl]-N-[(5P)-5-(pyrazin-2-yl)pyridin-2-yl]acetamide, 2C11 heavy chain, 2C11 light chain, ... | | Authors: | Liu, Y, Qi, X, Li, X. | | Deposit date: | 2022-04-21 | | Release date: | 2022-07-20 | | Last modified: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (2.92 Å) | | Cite: | Mechanisms and inhibition of Porcupine-mediated Wnt acylation.
Nature, 607, 2022
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5V93
 | | Cryo-EM structure of the 70S ribosome from Mycobacterium tuberculosis bound with Capreomycin | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Yang, K, Chang, J.-Y, Cui, Z, Li, X, Meng, R, Duan, L, Thongchol, J, Jakana, J, Huwe, C, Sacchettini, J, Zhang, J. | | Deposit date: | 2017-03-22 | | Release date: | 2017-09-20 | | Last modified: | 2020-08-12 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structural insights into species-specific features of the ribosome from the human pathogen Mycobacterium tuberculosis.
Nucleic Acids Res., 45, 2017
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5XR8
 | | Crystal structure of the human CB1 in complex with agonist AM841 | | Descriptor: | (6~{a}~{R},9~{R},10~{a}~{R})-9-(hydroxymethyl)-3-(8-isothiocyanato-2-methyl-octan-2-yl)-6,6-dimethyl-6~{a},7,8,9,10,10~{a}-hexahydrobenzo[c]chromen-1-ol, CHOLESTEROL, Cannabinoid receptor 1,Flavodoxin,Cannabinoid receptor 1, ... | | Authors: | Hua, T, Vemuri, K, Nikas, P.S, Laprairie, R.B, Wu, Y, Qu, L, Pu, M, Korde, A, Shan, J, Ho, J.H, Han, G.W, Ding, K, Li, X, Liu, H, Hanson, M.A, Zhao, S, Bohn, L.M, Makriyannis, A, Stevens, R.C, Liu, Z.J. | | Deposit date: | 2017-06-07 | | Release date: | 2017-07-12 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Crystal structures of agonist-bound human cannabinoid receptor CB1.
Nature, 547, 2017
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6KNM
 | | Apelin receptor in complex with single domain antibody | | Descriptor: | Apelin receptor,Rubredoxin,Apelin receptor, Single domain antibody JN241, ZINC ION | | Authors: | Ma, Y.B, Ding, Y, Song, X, Ma, X, Li, X, Zhang, N, Song, Y, Sun, Y, Shen, Y, Zhong, W, Hu, L.A, Ma, Y.L, Zhang, M.Y. | | Deposit date: | 2019-08-06 | | Release date: | 2020-01-29 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure-guided discovery of a single-domain antibody agonist against human apelin receptor.
Sci Adv, 6, 2020
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7VX2
 | | Crystal Structure of the Y53F/N55A/I80F/L114V/I116V mutant of LEH | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Qu, G, Li, X, Sun, Z.T, Han, X, Liu, W.D. | | Deposit date: | 2021-11-12 | | Release date: | 2023-01-18 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.485 Å) | | Cite: | Rational enzyme design for enabling biocatalytic Baldwin cyclization and asymmetric synthesis of chiral heterocycles.
Nat Commun, 13, 2022
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7VWD
 | | Crystal Structure of the Y53F/N55A mutant of LEH | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Qu, G, Li, X, Sun, Z.T, Han, X, Liu, W.D. | | Deposit date: | 2021-11-10 | | Release date: | 2023-01-18 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.153 Å) | | Cite: | Rational enzyme design for enabling biocatalytic Baldwin cyclization and asymmetric synthesis of chiral heterocycles.
Nat Commun, 13, 2022
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7VWM
 | | Crystal Structure of the Y53F/N55A/I116V mutant of LEH | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Qu, G, Li, X, Sun, Z.T, Han, X, Liu, W.D. | | Deposit date: | 2021-11-11 | | Release date: | 2023-01-18 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Rational enzyme design for enabling biocatalytic Baldwin cyclization and asymmetric synthesis of chiral heterocycles.
Nat Commun, 13, 2022
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6L4S
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7XLT
 | | Cryo-EM Structure of R-loop monoclonal antibody S9.6 in recognizing RNA:DNA hybrids | | Descriptor: | DNA, RNA, S9.6 Fab HC, ... | | Authors: | Li, Q, Lin, C, Luo, Z, Li, H, Li, X, Sun, Q. | | Deposit date: | 2022-04-22 | | Release date: | 2022-05-25 | | Last modified: | 2022-08-03 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Cryo-EM structure of R-loop monoclonal antibody S9.6 in recognizing RNA:DNA hybrids.
J Genet Genomics, 49, 2022
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5ZV7
 | | P domain of GII.17-2014/15 complexed with B-trisaccharide | | Descriptor: | VP1, alpha-L-fucopyranose-(1-2)-[alpha-D-galactopyranose-(1-3)]alpha-D-galactopyranose | | Authors: | Chen, Y, Li, X. | | Deposit date: | 2018-05-09 | | Release date: | 2018-10-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural Adaptations of Norovirus GII.17/13/21 Lineage through Two Distinct Evolutionary Paths.
J. Virol., 93, 2019
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5ZVC
 | | P domain of GII.13 norovirus capsid complexed with Lewis A trisaccharide | | Descriptor: | GLYCEROL, Major capsid protein VP1, beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Chen, Y, Li, X. | | Deposit date: | 2018-05-10 | | Release date: | 2018-10-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Adaptations of Norovirus GII.17/13/21 Lineage through Two Distinct Evolutionary Paths.
J. Virol., 93, 2019
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5ZV9
 | | P domain of GII.13 norovirus capsid | | Descriptor: | GLYCEROL, Major capsid protein VP1 | | Authors: | Chen, Y, Li, X. | | Deposit date: | 2018-05-09 | | Release date: | 2018-10-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Adaptations of Norovirus GII.17/13/21 Lineage through Two Distinct Evolutionary Paths.
J. Virol., 93, 2019
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5ZV5
 | | P domain of GII.17-2014/15 complexed with A-trisaccharide | | Descriptor: | VP1, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]alpha-D-galactopyranose | | Authors: | Chen, Y, Li, X. | | Deposit date: | 2018-05-09 | | Release date: | 2018-10-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Adaptations of Norovirus GII.17/13/21 Lineage through Two Distinct Evolutionary Paths.
J. Virol., 93, 2019
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5ZUQ
 | | P domain of GII.17-1978 | | Descriptor: | VP1 | | Authors: | Chen, Y, Li, X. | | Deposit date: | 2018-05-08 | | Release date: | 2018-10-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Structural Adaptations of Norovirus GII.17/13/21 Lineage through Two Distinct Evolutionary Paths.
J. Virol., 93, 2019
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5ZUS
 | | P domain of GII.17-2014/15 | | Descriptor: | VP1 | | Authors: | Chen, Y, Li, X. | | Deposit date: | 2018-05-08 | | Release date: | 2018-10-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Adaptations of Norovirus GII.17/13/21 Lineage through Two Distinct Evolutionary Paths.
J. Virol., 93, 2019
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8G05
 | | Cryo-EM structure of an orphan GPCR-Gi protein signaling complex | | Descriptor: | 6-(octylamino)pyrimidine-2,4(3H,5H)-dione, CHOLESTEROL, G-protein coupled receptor 84, ... | | Authors: | Zhang, X, Wang, Y.J, Li, X, Liu, G.B, Gong, W.M, Zhang, C. | | Deposit date: | 2023-01-31 | | Release date: | 2023-11-01 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Pro-phagocytic function and structural basis of GPR84 signaling.
Nat Commun, 14, 2023
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7XEF
 | | Crystal Structure of the Y53F/N55A mutant of LEH complexed with (R)-(1-benzyl-3-phenylpyrrolidin-3-yl)methanol | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Limonene-1,2-epoxide hydrolase, ... | | Authors: | Qu, G, Li, X, Sun, Z.T. | | Deposit date: | 2022-03-31 | | Release date: | 2023-01-18 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.816 Å) | | Cite: | Rational enzyme design for enabling biocatalytic Baldwin cyclization and asymmetric synthesis of chiral heterocycles.
Nat Commun, 13, 2022
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